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conduct disorder

MedGen UID:
56196
•Concept ID:
C0149654
•
Mental or Behavioral Dysfunction
Synonyms: Conduct Disorder; Conduct Disorders
SNOMED CT: Conduct disorder (430909002)
 
Monarch Initiative: MONDO:0005352

Definition

A disorder diagnosed in childhood or adolescence age group characterized by aggressive behavior, deceitfulness, destruction of property or violation of rules that is persistent and repetitive, and within a one year period. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVconduct disorder

Professional guidelines

PubMed

Sex differences in factors predicting post-treatment opioid use.
Davis JP, Eddie D, Prindle J, Dworkin ER, Christie NC, Saba S, DiGuiseppi GT, Clapp JD, Kelly JF
Addiction 2021 Aug;116(8):2116-2126. Epub 2021 Jan 22 doi: 10.1111/add.15396. PMID: 33405314Free PMC Article
Conduct disorders and psychopathy in children and adolescents: aetiology, clinical presentation and treatment strategies of callous-unemotional traits.
Pisano S, Muratori P, Gorga C, Levantini V, Iuliano R, Catone G, Coppola G, Milone A, Masi G
Ital J Pediatr 2017 Sep 20;43(1):84. doi: 10.1186/s13052-017-0404-6. PMID: 28931400Free PMC Article
The pharmacological management of oppositional behaviour, conduct problems, and aggression in children and adolescents with attention-deficit hyperactivity disorder, oppositional defiant disorder, and conduct disorder: a systematic review and meta-analysis. Part 1: psychostimulants, alpha-2 agonists, and atomoxetine.
Pringsheim T, Hirsch L, Gardner D, Gorman DA
Can J Psychiatry 2015 Feb;60(2):42-51. doi: 10.1177/070674371506000202. PMID: 25886655Free PMC Article

Recent clinical studies

Etiology

Conduct disorder.
Fairchild G, Hawes DJ, Frick PJ, Copeland WE, Odgers CL, Franke B, Freitag CM, De Brito SA
Nat Rev Dis Primers 2019 Jun 27;5(1):43. doi: 10.1038/s41572-019-0095-y. PMID: 31249310
Conduct Disorder: Recognition and Management.
Lillig M
Am Fam Physician 2018 Nov 15;98(10):584-592. PMID: 30365289
Genetic influences on conduct disorder.
Salvatore JE, Dick DM
Neurosci Biobehav Rev 2018 Aug;91:91-101. Epub 2016 Jun 24 doi: 10.1016/j.neubiorev.2016.06.034. PMID: 27350097Free PMC Article
Conduct disorders and psychopathy in children and adolescents: aetiology, clinical presentation and treatment strategies of callous-unemotional traits.
Pisano S, Muratori P, Gorga C, Levantini V, Iuliano R, Catone G, Coppola G, Milone A, Masi G
Ital J Pediatr 2017 Sep 20;43(1):84. doi: 10.1186/s13052-017-0404-6. PMID: 28931400Free PMC Article
Juvenile Firesetting.
Peters B, Freeman B
Child Adolesc Psychiatr Clin N Am 2016 Jan;25(1):99-106. Epub 2015 Oct 21 doi: 10.1016/j.chc.2015.08.009. PMID: 26593122

Diagnosis

Contemporary diagnosis and treatment of conduct disorder in youth.
Masi G, Carucci S, Muratori P, Balia C, Sesso G, Milone A
Expert Rev Neurother 2023 Jul-Dec;23(12):1277-1296. Epub 2023 Dec 15 doi: 10.1080/14737175.2023.2271169. PMID: 37853718
Conduct disorder.
Nat Rev Dis Primers 2019 Jun 27;5(1):44. doi: 10.1038/s41572-019-0100-5. PMID: 31249311
Conduct disorder.
Fairchild G, Hawes DJ, Frick PJ, Copeland WE, Odgers CL, Franke B, Freitag CM, De Brito SA
Nat Rev Dis Primers 2019 Jun 27;5(1):43. doi: 10.1038/s41572-019-0095-y. PMID: 31249310
Conduct Disorder: Recognition and Management.
Lillig M
Am Fam Physician 2018 Nov 15;98(10):584-592. PMID: 30365289
Conduct disorders and psychopathy in children and adolescents: aetiology, clinical presentation and treatment strategies of callous-unemotional traits.
Pisano S, Muratori P, Gorga C, Levantini V, Iuliano R, Catone G, Coppola G, Milone A, Masi G
Ital J Pediatr 2017 Sep 20;43(1):84. doi: 10.1186/s13052-017-0404-6. PMID: 28931400Free PMC Article

Therapy

Contemporary diagnosis and treatment of conduct disorder in youth.
Masi G, Carucci S, Muratori P, Balia C, Sesso G, Milone A
Expert Rev Neurother 2023 Jul-Dec;23(12):1277-1296. Epub 2023 Dec 15 doi: 10.1080/14737175.2023.2271169. PMID: 37853718
Using antipsychotics for behavioral problems in children.
Shafiq S, Pringsheim T
Expert Opin Pharmacother 2018 Sep;19(13):1475-1488. Epub 2018 Aug 13 doi: 10.1080/14656566.2018.1509069. PMID: 30102079
Treatment of behavioral and psychological symptoms of dementia: a systematic review.
Preuss UW, Wong JW, Koller G
Psychiatr Pol 2016;50(4):679-715. doi: 10.12740/PP/64477. PMID: 27847922
Clinical Factor 2015.
Balon R
Psychother Psychosom 2016;85(6):327-336. Epub 2016 Oct 15 doi: 10.1159/000448788. PMID: 27744435
Pharmacotherapy of conduct disorder: Challenges, options and future directions.
Hambly JL, Khan S, McDermott B, Bor W, Haywood A
J Psychopharmacol 2016 Oct;30(10):967-75. Epub 2016 Jul 19 doi: 10.1177/0269881116658985. PMID: 27436231

Prognosis

Conduct Disorder in Immigrant Children and Adolescents: A Nationwide Cohort Study in Sweden.
Osooli M, Ohlsson H, Sundquist J, Sundquist K
Int J Environ Res Public Health 2021 Oct 11;18(20) doi: 10.3390/ijerph182010643. PMID: 34682389Free PMC Article
Risperidone in the management of disruptive behavior disorders.
Pandina GJ, Aman MG, Findling RL
J Child Adolesc Psychopharmacol 2006 Aug;16(4):379-92. doi: 10.1089/cap.2006.16.379. PMID: 16958564
Current perspectives on conduct disorder.
Frick PJ, Dickens C
Curr Psychiatry Rep 2006 Feb;8(1):59-72. doi: 10.1007/s11920-006-0082-3. PMID: 16513044
Prevalence and development of psychiatric disorders in childhood and adolescence.
Costello EJ, Mustillo S, Erkanli A, Keeler G, Angold A
Arch Gen Psychiatry 2003 Aug;60(8):837-44. doi: 10.1001/archpsyc.60.8.837. PMID: 12912767
Hyperkinetic or attention deficit disorder.
Sandberg S
Br J Psychiatry 1996 Jul;169(1):10-7. doi: 10.1192/bjp.169.1.10. PMID: 8818362

Clinical prediction guides

Conduct disorder - a comprehensive exploration of comorbidity patterns, genetic and environmental risk factors.
Tesli N, Jaholkowski P, Haukvik UK, Jangmo A, Haram M, Rokicki J, Friestad C, Tielbeek JJ, Næss Ø, Skardhamar T, Gustavson K, Ask H, Fazel S, Tesli M, Andreassen OA
Psychiatry Res 2024 Jan;331:115628. Epub 2023 Nov 25 doi: 10.1016/j.psychres.2023.115628. PMID: 38029627
Editorial: Conduct Disorder and Its 70-Year History: Lessons From Hervey Cleckley and Lee Robins.
Salekin RT
J Am Acad Child Adolesc Psychiatry 2024 Apr;63(4):404-406. Epub 2023 Aug 30 doi: 10.1016/j.jaac.2023.08.007. PMID: 37657498
Psychopathy among condemned capital murderers.
DeLisi M, Peters DJ, Hochstetler A, Butler HD, Vaughn MG
J Forensic Sci 2023 Mar;68(2):558-567. Epub 2022 Dec 26 doi: 10.1111/1556-4029.15188. PMID: 36572956
Perpetrators and victims of cyberbullying among youth with conduct disorder.
Baumann S, Bernhard A, Martinelli A, Ackermann K, Herpertz-Dahlmann B, Freitag C, Konrad K, Kohls G
Eur Child Adolesc Psychiatry 2023 Sep;32(9):1643-1653. Epub 2022 Mar 29 doi: 10.1007/s00787-022-01973-0. PMID: 35348888Free PMC Article
Psychometric properties of the Screen for Child Anxiety Related Emotional Disorders (SCARED): a replication study.
Birmaher B, Brent DA, Chiappetta L, Bridge J, Monga S, Baugher M
J Am Acad Child Adolesc Psychiatry 1999 Oct;38(10):1230-6. doi: 10.1097/00004583-199910000-00011. PMID: 10517055

Recent systematic reviews

Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.
GBD 2019 Mental Disorders Collaborators
Lancet Psychiatry 2022 Feb;9(2):137-150. Epub 2022 Jan 10 doi: 10.1016/S2215-0366(21)00395-3. PMID: 35026139Free PMC Article
Systematic Review of Electronic Cigarette Use (Vaping) and Mental Health Comorbidity Among Adolescents and Young Adults.
Becker TD, Arnold MK, Ro V, Martin L, Rice TR
Nicotine Tob Res 2021 Feb 16;23(3):415-425. doi: 10.1093/ntr/ntaa171. PMID: 32905589
Mental Health Mobile Apps for Preadolescents and Adolescents: A Systematic Review.
Grist R, Porter J, Stallard P
J Med Internet Res 2017 May 25;19(5):e176. doi: 10.2196/jmir.7332. PMID: 28546138Free PMC Article
Treatment of behavioral and psychological symptoms of dementia: a systematic review.
Preuss UW, Wong JW, Koller G
Psychiatr Pol 2016;50(4):679-715. doi: 10.12740/PP/64477. PMID: 27847922
The pharmacological management of oppositional behaviour, conduct problems, and aggression in children and adolescents with attention-deficit hyperactivity disorder, oppositional defiant disorder, and conduct disorder: a systematic review and meta-analysis. Part 1: psychostimulants, alpha-2 agonists, and atomoxetine.
Pringsheim T, Hirsch L, Gardner D, Gorman DA
Can J Psychiatry 2015 Feb;60(2):42-51. doi: 10.1177/070674371506000202. PMID: 25886655Free PMC Article

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