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Closed comedo

MedGen UID:
549853
•Concept ID:
C0302302
•
Pathologic Function
Synonyms: Closed comedone; Whitehead
SNOMED CT: Whitehead (247468003); Closed comedone (247468003)
 
HPO: HP:0025250

Definition

A comedo in which the top of the pore is not stretched open and thus does not expose the clogged portion (which would appear black), hence the name whitehead. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVClosed comedo

Professional guidelines

PubMed

Topical antimicrobial peptides in combined treatment of acne patients.
Ma Z, Kochergin N, Olisova O, Snarskaya E
J Cosmet Dermatol 2022 Apr;21(4):1533-1538. Epub 2021 Jul 21 doi: 10.1111/jocd.14300. PMID: 34143573

Recent clinical studies

Etiology

Topical antimicrobial peptides in combined treatment of acne patients.
Ma Z, Kochergin N, Olisova O, Snarskaya E
J Cosmet Dermatol 2022 Apr;21(4):1533-1538. Epub 2021 Jul 21 doi: 10.1111/jocd.14300. PMID: 34143573
Accumulation of lipid peroxide in the content of comedones may be involved in the progression of comedogenesis and inflammatory changes in comedones.
Tochio T, Tanaka H, Nakata S, Ikeno H
J Cosmet Dermatol 2009 Jun;8(2):152-8. doi: 10.1111/j.1473-2165.2009.00437.x. PMID: 19527342

Diagnosis

A polypous carbuncle.
Meffert JJ
Int J Dermatol 1998 Apr;37(4):267-8. doi: 10.1046/j.1365-4362.1998.00379.x. PMID: 9585897

Prognosis

Topical antimicrobial peptides in combined treatment of acne patients.
Ma Z, Kochergin N, Olisova O, Snarskaya E
J Cosmet Dermatol 2022 Apr;21(4):1533-1538. Epub 2021 Jul 21 doi: 10.1111/jocd.14300. PMID: 34143573

Clinical prediction guides

Topical antimicrobial peptides in combined treatment of acne patients.
Ma Z, Kochergin N, Olisova O, Snarskaya E
J Cosmet Dermatol 2022 Apr;21(4):1533-1538. Epub 2021 Jul 21 doi: 10.1111/jocd.14300. PMID: 34143573

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