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Tarsal tunnel syndrome

MedGen UID:
52646
•Concept ID:
C0039319
•
Disease or Syndrome
Synonyms: Neuropathy of the posterior tibial nerve and its branches; Posterior Tibial Nerve Neuralgia
SNOMED CT: TTS - Tarsal tunnel syndrome (47374004); Tarsal tunnel syndrome (ankle condition) (47374004); Tarsal tunnel syndrome (47374004)
 
Monarch Initiative: MONDO:0006994

Definition

A syndrome resulting from the entrapment and compression of the tibial nerve. Signs and symptoms include burning sensation, tingling, and pain in the foot sole. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTarsal tunnel syndrome

Professional guidelines

PubMed

Rearfoot disorders and conservative treatment: a narrative review.
Choo YJ, Park CH, Chang MC
Ann Palliat Med 2020 Sep;9(5):3546-3552. Epub 2020 Aug 6 doi: 10.21037/apm-20-446. PMID: 32787369
Heel Pain: Diagnosis and Management.
Tu P
Am Fam Physician 2018 Jan 15;97(2):86-93. PMID: 29365222
Plantar and medial heel pain: diagnosis and management.
Lareau CR, Sawyer GA, Wang JH, DiGiovanni CW
J Am Acad Orthop Surg 2014 Jun;22(6):372-80. doi: 10.5435/JAAOS-22-06-372. PMID: 24860133

Recent clinical studies

Etiology

Ganglia-Induced Tarsal Tunnel Syndrome.
Koketsu K, Kim K, Tajiri T, Isu T, Morimoto D, Kokubo R, Dan H, Morita A
J Nippon Med Sch 2024;91(1):114-118. doi: 10.1272/jnms.JNMS.2024_91-203. PMID: 38462440
Tarsal Tunnel Syndrome: Outcome According to Etiology.
Lalevée M, Coillard JY, Gauthé R, Dechelotte B, Fantino O, Boublil D, Grisard JL, Viste A, Klouche S, Bouysset M
J Foot Ankle Surg 2022 May-Jun;61(3):583-589. Epub 2021 Oct 23 doi: 10.1053/j.jfas.2021.10.014. PMID: 34799273
Calcaneal osteotomy for hindfoot deformity.
Brilhault J
Orthop Traumatol Surg Res 2022 Feb;108(1S):103121. Epub 2021 Oct 20 doi: 10.1016/j.otsr.2021.103121. PMID: 34687951
Tarsal tunnel syndrome-A narrative literature review.
McSweeney SC, Cichero M
Foot (Edinb) 2015 Dec;25(4):244-50. Epub 2015 Sep 12 doi: 10.1016/j.foot.2015.08.008. PMID: 26546070
Controversial entrapment neuropathies.
Campbell WW, Landau ME
Neurosurg Clin N Am 2008 Oct;19(4):597-608, vi-vii. doi: 10.1016/j.nec.2008.07.001. PMID: 19010284

Diagnosis

Tarsal Tunnel Syndrome.
Nelson SC
Clin Podiatr Med Surg 2021 Apr;38(2):131-141. doi: 10.1016/j.cpm.2020.12.001. PMID: 33745647
Lower extremity entrapment neuropathies.
Madani S, Doughty C
Best Pract Res Clin Rheumatol 2020 Jun;34(3):101565. Epub 2020 Jul 31 doi: 10.1016/j.berh.2020.101565. PMID: 32747188
Entrapment Neuropathies of the Lower Extremity.
Bowley MP, Doughty CT
Med Clin North Am 2019 Mar;103(2):371-382. Epub 2018 Dec 3 doi: 10.1016/j.mcna.2018.10.013. PMID: 30704688
Heel Pain: Diagnosis and Management.
Tu P
Am Fam Physician 2018 Jan 15;97(2):86-93. PMID: 29365222
Tarsal tunnel syndrome.
Gould JS
Foot Ankle Clin 2011 Jun;16(2):275-86. doi: 10.1016/j.fcl.2011.01.008. PMID: 21600447

Therapy

Acupotomy for patients with tarsal tunnel syndrome: A protocol for systematic review and meta analysis.
Sun X, Zhou Q, Shi C, Lan Y, Jia Y, Qiu Z, Shen Y, Li S
Medicine (Baltimore) 2020 Sep 25;99(39):e22369. doi: 10.1097/MD.0000000000022369. PMID: 32991456Free PMC Article
Managing the patient with heel pain.
Bhatty UN, Khan SH, Zubairy AI
Br J Hosp Med (Lond) 2019 Apr 2;80(4):196-200. doi: 10.12968/hmed.2019.80.4.196. PMID: 30951414
Tarsal tunnel syndrome-A narrative literature review.
McSweeney SC, Cichero M
Foot (Edinb) 2015 Dec;25(4):244-50. Epub 2015 Sep 12 doi: 10.1016/j.foot.2015.08.008. PMID: 26546070
Considerations in footwear and orthotics.
Khan MN, Jacobs BC, Ashbaugh S
Prim Care 2013 Dec;40(4):1001-12, x. Epub 2013 Oct 15 doi: 10.1016/j.pop.2013.08.013. PMID: 24209730
Burning feet.
Br Med J 1972 Jul 22;3(5820):193. PMID: 5040704Free PMC Article

Prognosis

Ultrasound Imaging of the Deep Peroneal Nerve.
Becciolini M, Pivec C, Riegler G
J Ultrasound Med 2021 Apr;40(4):821-838. Epub 2020 Sep 3 doi: 10.1002/jum.15455. PMID: 32881065
Tarsal tunnel syndrome-A narrative literature review.
McSweeney SC, Cichero M
Foot (Edinb) 2015 Dec;25(4):244-50. Epub 2015 Sep 12 doi: 10.1016/j.foot.2015.08.008. PMID: 26546070
Diagnosis of heel pain.
Tu P, Bytomski JR
Am Fam Physician 2011 Oct 15;84(8):909-16. PMID: 22010770
Peripheral nerve entrapments.
Hirose CB, McGarvey WC
Foot Ankle Clin 2004 Jun;9(2):255-69. doi: 10.1016/j.fcl.2004.02.001. PMID: 15165581
Backpacking-induced paresthesias.
Boulware DR
Wilderness Environ Med 2003 Fall;14(3):161-6. doi: 10.1580/1080-6032(2003)14[161:bp]2.0.co;2. PMID: 14518626

Clinical prediction guides

Ganglia-Induced Tarsal Tunnel Syndrome.
Koketsu K, Kim K, Tajiri T, Isu T, Morimoto D, Kokubo R, Dan H, Morita A
J Nippon Med Sch 2024;91(1):114-118. doi: 10.1272/jnms.JNMS.2024_91-203. PMID: 38462440
The bifurcation and topography of the posterior tibial artery within the tarsal tunnel.
Marchese B, McDonald A, McGowan H
Surg Radiol Anat 2023 May;45(5):611-622. Epub 2023 Mar 13 doi: 10.1007/s00276-023-03115-w. PMID: 36912942Free PMC Article
Patient Satisfaction with Surgery for Tarsal- and Carpal- Tunnel Syndrome - Comparative Study.
Kokubo R, Kim K, Isu T, Morimoto D, Morita A
Neurol Med Chir (Tokyo) 2023 Mar 15;63(3):116-121. Epub 2023 Jan 20 doi: 10.2176/jns-nmc.2022-0245. PMID: 36682791Free PMC Article
Results of surgical treatment of tarsal tunnel syndrome.
Reichert P, Zimmer K, Wnukiewicz W, Kuliński S, Mazurek P, Gosk J
Foot Ankle Surg 2015 Mar;21(1):26-9. Epub 2014 Sep 9 doi: 10.1016/j.fas.2014.08.013. PMID: 25682403
Tarsal tunnel syndrome: A literature review.
Ahmad M, Tsang K, Mackenney PJ, Adedapo AO
Foot Ankle Surg 2012 Sep;18(3):149-52. Epub 2011 Dec 21 doi: 10.1016/j.fas.2011.10.007. PMID: 22857954

Recent systematic reviews

Tarsal tunnel syndrome secondary to accessory or variant muscles: a clinical and anatomical systematic review.
Yammine K, Daher JC, Tannoury EH, Assi C
Surg Radiol Anat 2022 May;44(5):645-657. Epub 2022 Mar 30 doi: 10.1007/s00276-022-02932-9. PMID: 35353216
Anatomical characteristics of the flexor digitorum accessorius longus muscle and their relevance to tarsal tunnel syndrome a systematic review.
Deleu PA, Bevernage BD, Birch I, Maldague P, Gombault V, Leemrijse T
J Am Podiatr Med Assoc 2015 Jul;105(4):344-55. doi: 10.7547/13-084.1. PMID: 26218158
Outcomes and safety of endoscopic tarsal tunnel decompression: a systematic review.
Gkotsoulias EN, Simonson DC, Roukis TS
Foot Ankle Spec 2014 Feb;7(1):57-60. Epub 2013 Dec 10 doi: 10.1177/1938640013514267. PMID: 24334368
Neurologic involvement in scleroderma: a systematic review.
Amaral TN, Peres FA, Lapa AT, Marques-Neto JF, Appenzeller S
Semin Arthritis Rheum 2013 Dec;43(3):335-47. Epub 2013 Jul 1 doi: 10.1016/j.semarthrit.2013.05.002. PMID: 23827688

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