U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Kidney hypertrophy

MedGen UID:
510218
Concept ID:
C0156259
Disease or Syndrome
Synonyms: Hypertrophy of kidney; hypertrophy of the kidney; kidney hypertrophy; Renal Hypertrophy; renal Hypertrophy
SNOMED CT: Hypertrophy of kidney (88531004)
 
Monarch Initiative: MONDO:0004841

Definition

Global enlargement of the renal parenchyma in one or both kidneys. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Germain DP, Altarescu G, Barriales-Villa R, Mignani R, Pawlaczyk K, Pieruzzi F, Terryn W, Vujkovac B, Ortiz A
Mol Genet Metab 2022 Sep-Oct;137(1-2):49-61. Epub 2022 Jul 26 doi: 10.1016/j.ymgme.2022.07.010. PMID: 35926321
Rabi DM, McBrien KA, Sapir-Pichhadze R, Nakhla M, Ahmed SB, Dumanski SM, Butalia S, Leung AA, Harris KC, Cloutier L, Zarnke KB, Ruzicka M, Hiremath S, Feldman RD, Tobe SW, Campbell TS, Bacon SL, Nerenberg KA, Dresser GK, Fournier A, Burgess E, Lindsay P, Rabkin SW, Prebtani APH, Grover S, Honos G, Alfonsi JE, Arcand J, Audibert F, Benoit G, Bittman J, Bolli P, Côté AM, Dionne J, Don-Wauchope A, Edwards C, Firoz T, Gabor JY, Gilbert RE, Grégoire JC, Gryn SE, Gupta M, Hannah-Shmouni F, Hegele RA, Herman RJ, Hill MD, Howlett JG, Hundemer GL, Jones C, Kaczorowski J, Khan NA, Kuyper LM, Lamarre-Cliche M, Lavoie KL, Leiter LA, Lewanczuk R, Logan AG, Magee LA, Mangat BK, McFarlane PA, McLean D, Michaud A, Milot A, Moe GW, Penner SB, Pipe A, Poppe AY, Rey E, Roerecke M, Schiffrin EL, Selby P, Sharma M, Shoamanesh A, Sivapalan P, Townsend RR, Tran K, Trudeau L, Tsuyuki RT, Vallée M, Woo V, Bell AD, Daskalopoulou SS
Can J Cardiol 2020 May;36(5):596-624. doi: 10.1016/j.cjca.2020.02.086. PMID: 32389335
Mercado MG, Smith DK, Guard EL
Am Fam Physician 2019 Dec 1;100(11):687-694. PMID: 31790176

Recent clinical studies

Etiology

Alcalde-Ortiz ML, Jaramillo-Arriaga F, Ibarra-Orenday D, González-Domínguez SI, Calzada-Gallegos HD, Pinales-Jiménez AA, Carrillo-Aguilera IA, Flota-Marin DA, Collazo-Zamores MG, Aguirre-Moreno PD, Gutiérrez-Hernández SD, Del Toro-Delgado V, Delgadillo-Castañeda R, Sánchez-Ortiz MDR, Sánchez-González I, Ramos-Medellin CL, Chew-Wong A, Macias-Díaz DM, Arreola-Guerra JM
Kidney Int 2024 Apr;105(4):824-834. Epub 2024 Jan 25 doi: 10.1016/j.kint.2023.11.034. PMID: 38280517
Sharma K, Zhang G, Hansen J, Bjornstad P, Lee HJ, Menon R, Hejazi L, Liu JJ, Franzone A, Looker HC, Choi BY, Fernandez R, Venkatachalam MA, Kugathasan L, Sridhar VS, Natarajan L, Zhang J, Sharma VS, Kwan B, Waikar SS, Himmelfarb J, Tuttle KR, Kestenbaum B, Fuhrer T, Feldman HI, de Boer IH, Tucci FC, Sedor J, Heerspink HL, Schaub J, Otto EA, Hodgin JB, Kretzler M, Anderton CR, Alexandrov T, Cherney D, Lim SC, Nelson RG, Gelfond J, Iyengar R; Kidney Precision Medicine Project
J Clin Invest 2023 Oct 16;133(20) doi: 10.1172/JCI170341. PMID: 37616058Free PMC Article
Chu DI, Ehlayel AM, Ginsberg JP, Meyers KE, Benton M, Thomas M, Carlson C, Kolon TF, Tasian GE, Greenberg JH, Furth SL, Denburg MR
J Pediatr 2021 Mar;230:215-220.e1. Epub 2020 Dec 5 doi: 10.1016/j.jpeds.2020.12.005. PMID: 33290810Free PMC Article
Garibotto G, Sofia A, Robaudo C, Saffioti S, Sala MR, Verzola D, Vettore M, Russo R, Procopio V, Deferrari G, Tessari P
J Am Soc Nephrol 2004 Jun;15(6):1606-15. doi: 10.1097/01.asn.0000127865.26968.36. PMID: 15153572
Dworkin LD
J Am Soc Nephrol 1990 Sep;1(3 Suppl 1):S21-7. PMID: 16989074

Diagnosis

Alcalde-Ortiz ML, Jaramillo-Arriaga F, Ibarra-Orenday D, González-Domínguez SI, Calzada-Gallegos HD, Pinales-Jiménez AA, Carrillo-Aguilera IA, Flota-Marin DA, Collazo-Zamores MG, Aguirre-Moreno PD, Gutiérrez-Hernández SD, Del Toro-Delgado V, Delgadillo-Castañeda R, Sánchez-Ortiz MDR, Sánchez-González I, Ramos-Medellin CL, Chew-Wong A, Macias-Díaz DM, Arreola-Guerra JM
Kidney Int 2024 Apr;105(4):824-834. Epub 2024 Jan 25 doi: 10.1016/j.kint.2023.11.034. PMID: 38280517
Polina I, Spicer MJ, Domondon M, Schibalski RS, Sarsenova E, Sultanova RF, Ilatovskaya DV
Ren Fail 2021 Dec;43(1):315-324. doi: 10.1080/0886022X.2021.1879856. PMID: 33541194Free PMC Article
Polidori N, Giannini C, Salvatore R, Pelliccia P, Parisi A, Chiarelli F, Mohn A
J Pediatr Endocrinol Metab 2020 Sep 25;33(9):1183-1189. doi: 10.1515/jpem-2020-0138. PMID: 32845866
Stefanowicz J, Kosiak M, Kosiak W, Korbus-Kosiak A, Sierota D, Owczuk R
Pediatr Blood Cancer 2010 Jan;54(1):41-6. doi: 10.1002/pbc.22249. PMID: 19774637
Reyes AA, Karl IE, Klahr S
Am J Physiol 1994 Sep;267(3 Pt 2):F331-46. doi: 10.1152/ajprenal.1994.267.3.F331. PMID: 8092248

Therapy

Parada-Ricart E, Ferre N, Luque V, Gruszfeld D, Gradowska K, Closa-Monasterolo R, Koletzko B, Grote V, Escribano Subías J
Nutrients 2023 Feb 9;15(4) doi: 10.3390/nu15040874. PMID: 36839233Free PMC Article
Steden K, Figiel J, Hoyer J, Kamalanabhaiah SR
Transplant Proc 2022 Apr;54(3):627-631. Epub 2022 Mar 3 doi: 10.1016/j.transproceed.2021.11.040. PMID: 35248353
Nishizono R, Kikuchi M, Wang SQ, Chowdhury M, Nair V, Hartman J, Fukuda A, Wickman L, Hodgin JB, Bitzer M, Naik A, Wiggins J, Kretzler M, Wiggins RC
J Am Soc Nephrol 2017 Oct;28(10):2931-2945. Epub 2017 Jul 18 doi: 10.1681/ASN.2017020174. PMID: 28720684Free PMC Article
Galindo P, González-Manzano S, Zarzuelo MJ, Gómez-Guzmán M, Quintela AM, González-Paramás A, Santos-Buelga C, Pérez-Vizcaíno F, Duarte J, Jiménez R
Food Funct 2012 Jun;3(6):643-50. doi: 10.1039/c2fo10268d. PMID: 22441211
Orskov H, Flyvbjerg A, Frystyk J, Ledet T, Møller N, Christensen SE, Harris AG
Metabolism 1992 Sep;41(9 Suppl 2):66-71. doi: 10.1016/0026-0495(92)90034-8. PMID: 1518436

Prognosis

Sharma K, Zhang G, Hansen J, Bjornstad P, Lee HJ, Menon R, Hejazi L, Liu JJ, Franzone A, Looker HC, Choi BY, Fernandez R, Venkatachalam MA, Kugathasan L, Sridhar VS, Natarajan L, Zhang J, Sharma VS, Kwan B, Waikar SS, Himmelfarb J, Tuttle KR, Kestenbaum B, Fuhrer T, Feldman HI, de Boer IH, Tucci FC, Sedor J, Heerspink HL, Schaub J, Otto EA, Hodgin JB, Kretzler M, Anderton CR, Alexandrov T, Cherney D, Lim SC, Nelson RG, Gelfond J, Iyengar R; Kidney Precision Medicine Project
J Clin Invest 2023 Oct 16;133(20) doi: 10.1172/JCI170341. PMID: 37616058Free PMC Article
Polidori N, Giannini C, Salvatore R, Pelliccia P, Parisi A, Chiarelli F, Mohn A
J Pediatr Endocrinol Metab 2020 Sep 25;33(9):1183-1189. doi: 10.1515/jpem-2020-0138. PMID: 32845866
Choi KH, Lee SR, Hong YK, Park DS
Urology 2017 Jun;104:115-121. Epub 2017 Feb 21 doi: 10.1016/j.urology.2017.02.022. PMID: 28232178
Stefanowicz J, Kosiak M, Kosiak W, Korbus-Kosiak A, Sierota D, Owczuk R
Pediatr Blood Cancer 2010 Jan;54(1):41-6. doi: 10.1002/pbc.22249. PMID: 19774637
Mullerad M, Kastin A, Issaq E, Moskovitz B, Groshar D, Nativ O
J Urol 2003 Jan;169(1):24-7. doi: 10.1016/S0022-5347(05)64026-8. PMID: 12478094

Clinical prediction guides

Sharma K, Zhang G, Hansen J, Bjornstad P, Lee HJ, Menon R, Hejazi L, Liu JJ, Franzone A, Looker HC, Choi BY, Fernandez R, Venkatachalam MA, Kugathasan L, Sridhar VS, Natarajan L, Zhang J, Sharma VS, Kwan B, Waikar SS, Himmelfarb J, Tuttle KR, Kestenbaum B, Fuhrer T, Feldman HI, de Boer IH, Tucci FC, Sedor J, Heerspink HL, Schaub J, Otto EA, Hodgin JB, Kretzler M, Anderton CR, Alexandrov T, Cherney D, Lim SC, Nelson RG, Gelfond J, Iyengar R; Kidney Precision Medicine Project
J Clin Invest 2023 Oct 16;133(20) doi: 10.1172/JCI170341. PMID: 37616058Free PMC Article
Steden K, Figiel J, Hoyer J, Kamalanabhaiah SR
Transplant Proc 2022 Apr;54(3):627-631. Epub 2022 Mar 3 doi: 10.1016/j.transproceed.2021.11.040. PMID: 35248353
Kaikini AA, Muke S, Peshattiwar V, Bagle S, Dighe V, Sathaye S
J Food Biochem 2021 Apr;45(4):e13607. Epub 2021 Feb 15 doi: 10.1111/jfbc.13607. PMID: 33587296
Polina I, Spicer MJ, Domondon M, Schibalski RS, Sarsenova E, Sultanova RF, Ilatovskaya DV
Ren Fail 2021 Dec;43(1):315-324. doi: 10.1080/0886022X.2021.1879856. PMID: 33541194Free PMC Article
Fang F, Bae EH, Hu A, Liu GC, Zhou X, Williams V, Maksimowski N, Lu C, Konvalinka A, John R, Scholey JW
Diabetologia 2015 Jul;58(7):1668-78. Epub 2015 May 10 doi: 10.1007/s00125-015-3605-9. PMID: 25957229

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...