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Osseous finger syndactyly

MedGen UID:
488792
•Concept ID:
C0158736
•
Congenital Abnormality
Synonyms: Complex syndactyly of fingers; Osseous syndactyly of fingers; Osseous syndactyly of the fingers; Syndactyly of fingers with fusion of bones
SNOMED CT: Complex syndactyly of fingers (2560006); Osseous syndactyly of fingers (2560006); Syndactyly of fingers with fusion of bones (2560006)
 
HPO: HP:0010492

Definition

Webbing or fusion of the fingers, involving soft parts and including fusion of individual finger bones. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOsseous finger syndactyly

Professional guidelines

PubMed

Central Coalition Osteotomy of Phalangeal Synostoses in the Management of the Type III Apert Hand.
Theman TA, Upton J, Taghinia AH, Firriolo JM, Nuzzi LC, Labow BI
J Hand Surg Am 2018 Nov;43(11):1042.e1-1042.e8. Epub 2018 Jun 8 doi: 10.1016/j.jhsa.2018.03.050. PMID: 29891270
Thumb in the plane of the hand: characterization and results of surgical treatment.
Langer JS, Manske PR, Steffen JA, Hu C, Goldfarb C
J Hand Surg Am 2009 Dec;34(10):1795-801. Epub 2009 Nov 7 doi: 10.1016/j.jhsa.2009.08.008. PMID: 19897326
Hand problems in children. A timetable for management.
Eaton RG
Pediatr Clin North Am 1967 Aug;14(3):643-58. doi: 10.1016/s0031-3955(16)32021-1. PMID: 4291319

Recent clinical studies

Etiology

Clinical Manifestations of Constriction Band Syndrome.
Demetri LRF, Starcevich AG, Manske MCB, James MA
J Bone Joint Surg Am 2022 Jul 20;104(14):1301-1310. Epub 2022 Apr 14 doi: 10.2106/JBJS.21.01286. PMID: 35856931
Distraction Lengthening of the Apert Thumb.
Upton J, McNamara CT, Ali B, Nuzzi LC, Taghinia AH, Labow BI
Plast Reconstr Surg 2022 Apr 1;149(4):691e-699e. doi: 10.1097/PRS.0000000000008929. PMID: 35157629
Oligodactyly with Thumb.
Baek GH, Kim J
J Hand Surg Asian Pac Vol 2016 Oct;21(3):283-91. doi: 10.1142/S2424835516400087. PMID: 27595943
Treatment of congenital syndactyly of the fingers.
Kvernmo HD, Haugstvedt JR
Tidsskr Nor Laegeforen 2013 Aug 20;133(15):1591-5. doi: 10.4045/tidsskr.13.0147. PMID: 23970273
Craniofrontonasal dysplasia.
Kapusta L, Brunner HG, Hamel BC
Eur J Pediatr 1992 Nov;151(11):837-41. doi: 10.1007/BF01957936. PMID: 1468459

Diagnosis

Hypothesis: Symbrachydactyly.
Holmes LB, Nasri HZ
Am J Med Genet A 2022 Nov;188(11):3236-3241. Epub 2022 Sep 8 doi: 10.1002/ajmg.a.62941. PMID: 36073773
Clinical Manifestations of Constriction Band Syndrome.
Demetri LRF, Starcevich AG, Manske MCB, James MA
J Bone Joint Surg Am 2022 Jul 20;104(14):1301-1310. Epub 2022 Apr 14 doi: 10.2106/JBJS.21.01286. PMID: 35856931
Reconstruction of congenital differences of the hand.
Bates SJ, Hansen SL, Jones NF
Plast Reconstr Surg 2009 Jul;124(1 Suppl):128e-143e. doi: 10.1097/PRS.0b013e3181a80777. PMID: 19568146
Fraser syndrome.
Chattopadhyay A, Kher AS, Udwadia AD, Sharma SV, Bharucha BA, Nicholson AD
J Postgrad Med 1993 Oct-Dec;39(4):228-30. PMID: 7996504
Craniofrontonasal dysplasia.
Kapusta L, Brunner HG, Hamel BC
Eur J Pediatr 1992 Nov;151(11):837-41. doi: 10.1007/BF01957936. PMID: 1468459

Therapy

A palmar approach for insertion of a free, nonvascularized phalangeal transfer.
Sammut D, Garagnani L
Tech Hand Up Extrem Surg 2012 Jun;16(2):114-7. doi: 10.1097/BTH.0b013e31825600fb. PMID: 22627940
Multiple malformations in a male and maternal osteopathia strata with cranial sclerosis (OSCS).
Rott HD, Krieg P, Rütschle H, Kraus C
Genet Couns 2003;14(3):281-8. PMID: 14577672
Humeroradial synostosis, ulnar aplasia and oligodactyly, with contralateral amelia, in a child with prenatal cocaine exposure.
Marles SL, Reed M, Evans JA
Am J Med Genet A 2003 Jan 1;116A(1):85-9. doi: 10.1002/ajmg.a.10731. PMID: 12476458
Phenocopies.
Lenz W
J Med Genet 1973 Mar;10(1):34-49. doi: 10.1136/jmg.10.1.34. PMID: 4354695Free PMC Article
The thumb in the congenital malformation syndromes.
Poznanski AK, Garn SM, Holt JF
Radiology 1971 Jul;100(1):115-29. doi: 10.1148/100.1.115. PMID: 5147019

Prognosis

Clinical Manifestations of Constriction Band Syndrome.
Demetri LRF, Starcevich AG, Manske MCB, James MA
J Bone Joint Surg Am 2022 Jul 20;104(14):1301-1310. Epub 2022 Apr 14 doi: 10.2106/JBJS.21.01286. PMID: 35856931
Five- and 10-Year Follow-Up of Nonvascularized Toe Phalanx Transfers.
Kawabata H, Tamura D
J Hand Surg Am 2018 May;43(5):485.e1-485.e5. Epub 2017 Dec 6 doi: 10.1016/j.jhsa.2017.10.034. PMID: 29223628
Macrodactyly.
Kotwal PP, Farooque M
J Bone Joint Surg Br 1998 Jul;80(4):651-3. doi: 10.1302/0301-620x.80b4.8489. PMID: 9699830
Craniofrontonasal dysplasia.
Kapusta L, Brunner HG, Hamel BC
Eur J Pediatr 1992 Nov;151(11):837-41. doi: 10.1007/BF01957936. PMID: 1468459
Congenital hand anomaly: etiology and associated malformations.
Goldberg MJ, Bartoshesky LE
Hand Clin 1985 Aug;1(3):405-15. PMID: 3007544

Clinical prediction guides

Efficacy of a fingertip reconstruction technique using the tongue-shaped flap and advancement flap for repairing congenital syndactyly with osseous fusion of the distal phalanges.
Cheng S, Gao W, Ding J, Zhou Z, Wang A
J Plast Reconstr Aesthet Surg 2023 Jun;81:1-6. Epub 2023 Feb 28 doi: 10.1016/j.bjps.2023.02.029. PMID: 37060893
Oligodactyly with Thumb.
Baek GH, Kim J
J Hand Surg Asian Pac Vol 2016 Oct;21(3):283-91. doi: 10.1142/S2424835516400087. PMID: 27595943
Craniofrontonasal dysplasia.
Kapusta L, Brunner HG, Hamel BC
Eur J Pediatr 1992 Nov;151(11):837-41. doi: 10.1007/BF01957936. PMID: 1468459
Cleft hand.
Ogino T
Hand Clin 1990 Nov;6(4):661-71. PMID: 2176655
Congenital hand anomaly: etiology and associated malformations.
Goldberg MJ, Bartoshesky LE
Hand Clin 1985 Aug;1(3):405-15. PMID: 3007544

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