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Myringosclerosis

MedGen UID:
488426
•Concept ID:
C3494473
•
Disease or Syndrome
Synonym: Myringoscleroses

Definition

The formation of dense connective tissue and calcification in the TYMPANIC MEMBRANE that does not necessarily cause or lead to loss of hearing. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMyringosclerosis

Professional guidelines

PubMed

The effect of Vitamin E treatment on the development of myringosclerosis after ventilation tube insertion.
Uneri C, Bağlam T, Yazici M
Int J Pediatr Otorhinolaryngol 2006 Jun;70(6):1045-8. Epub 2005 Dec 20 doi: 10.1016/j.ijporl.2005.10.019. PMID: 16368152
Late results of treatment with ventilation tubes for secretory otitis media in ENT practice.
Sederberg-Olsen JF, Sederberg-Olsen AE, Jensen AM
Acta Otolaryngol 1989 Nov-Dec;108(5-6):448-55. doi: 10.3109/00016488909125552. PMID: 2589073

Recent clinical studies

Etiology

Endoscopic transcanal management of tympanosclerosis.
Özdek A
Eur Arch Otorhinolaryngol 2022 Feb;279(2):677-683. Epub 2021 Feb 20 doi: 10.1007/s00405-021-06692-x. PMID: 33609176
Examination of hearing loss among school-aged children in Greenland.
Jensen JS, Schnohr C, Skovsen CF, Homøe P, Jensen RG
Int J Pediatr Otorhinolaryngol 2021 Oct;149:110865. Epub 2021 Aug 8 doi: 10.1016/j.ijporl.2021.110865. PMID: 34385040
Pediatric lateral graft tympanoplasty A review of 78 cases.
Zhan KY, Rawlins KW, Mattingly JK, Malhotra PS, Adunka OF
Int J Pediatr Otorhinolaryngol 2019 Apr;119:166-170. Epub 2019 Jan 28 doi: 10.1016/j.ijporl.2019.01.038. PMID: 30711838
Grommets in otitis media: a 25-year follow up.
Sederberg-Olsen JF, Sederberg-Olsen N, Holmelund M
Acta Otolaryngol 2018 Dec;138(12):1057-1060. Epub 2019 Jan 31 doi: 10.1080/00016489.2018.1511060. PMID: 30702024
Pretreatment factors affecting traumatic tympanic membrane regeneration therapy using epidermal growth factor.
Lou ZC, Wei H, Lou ZH
Am J Otolaryngol 2018 Nov-Dec;39(6):711-718. Epub 2018 Jul 27 doi: 10.1016/j.amjoto.2018.07.020. PMID: 30078511

Diagnosis

Tympanic membrane perforations: the importance of etiology, size and location.
Castelhano L, Correia F, Colaço T, Reis L, Escada P
Eur Arch Otorhinolaryngol 2022 Sep;279(9):4325-4333. Epub 2022 Jan 14 doi: 10.1007/s00405-021-07186-6. PMID: 35028696
Grommets in otitis media: a 25-year follow up.
Sederberg-Olsen JF, Sederberg-Olsen N, Holmelund M
Acta Otolaryngol 2018 Dec;138(12):1057-1060. Epub 2019 Jan 31 doi: 10.1080/00016489.2018.1511060. PMID: 30702024
Cilia and Ear.
Piatti G, De Santi MM, Torretta S, Pignataro L, Soi D, Ambrosetti U
Ann Otol Rhinol Laryngol 2017 Apr;126(4):322-327. Epub 2017 Feb 12 doi: 10.1177/0003489417691299. PMID: 28290230
The windows of the inner ear.
Thomson S, Madani G
Clin Radiol 2014 Mar;69(3):e146-52. Epub 2013 Dec 22 doi: 10.1016/j.crad.2013.10.020. PMID: 24365668
Hearing loss.
Weissman JL
Radiology 1996 Jun;199(3):593-611. doi: 10.1148/radiology.199.3.8637972. PMID: 8637972

Therapy

Myringosclerosis as a predictor of the requirement for a permanent pacemaker in patients with drug-related atrioventricular block.
Cosgun MS, Hamur H, Degirmenci H, Coskun R, Karayumak MR, Karabiyik U, Salcan I
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2022 Dec;166(4):412-417. Epub 2022 Jun 21 doi: 10.5507/bp.2022.030. PMID: 35734916
Pediatric lateral graft tympanoplasty A review of 78 cases.
Zhan KY, Rawlins KW, Mattingly JK, Malhotra PS, Adunka OF
Int J Pediatr Otorhinolaryngol 2019 Apr;119:166-170. Epub 2019 Jan 28 doi: 10.1016/j.ijporl.2019.01.038. PMID: 30711838
Pretreatment factors affecting traumatic tympanic membrane regeneration therapy using epidermal growth factor.
Lou ZC, Wei H, Lou ZH
Am J Otolaryngol 2018 Nov-Dec;39(6):711-718. Epub 2018 Jul 27 doi: 10.1016/j.amjoto.2018.07.020. PMID: 30078511
Stapes Release in Tympanosclerosis.
Bedri EH, Teferi N, Redleaf M
Otol Neurotol 2018 Feb;39(2):184-188. doi: 10.1097/MAO.0000000000001639. PMID: 29210944
Shepard grommet tympanostomy tube complications in children with chronic otitis media with effusion.
Yaman H, Yilmaz S, Alkan N, Subasi B, Guclu E, Ozturk O
Eur Arch Otorhinolaryngol 2010 Aug;267(8):1221-4. Epub 2010 Mar 5 doi: 10.1007/s00405-010-1220-4. PMID: 20204390

Prognosis

Hearing outcome after tympanoplasty type III.
Tihanyi A, Speck I, Wolff K, Arnold P, Aschendorff A, Arndt S
Eur Arch Otorhinolaryngol 2022 Sep;279(9):4353-4362. Epub 2022 Jan 24 doi: 10.1007/s00405-021-07190-w. PMID: 35072768Free PMC Article
Tympanic membrane perforations: the importance of etiology, size and location.
Castelhano L, Correia F, Colaço T, Reis L, Escada P
Eur Arch Otorhinolaryngol 2022 Sep;279(9):4325-4333. Epub 2022 Jan 14 doi: 10.1007/s00405-021-07186-6. PMID: 35028696
The evaluation of prognostic factors in endoscopic cartilage tympanoplasty.
Dursun E, Terzi S, Demir E, Özgür A, Çelebi Erdivanlı Ö, Özergin Coşkun Z, Çeliker M
Eur Arch Otorhinolaryngol 2020 Oct;277(10):2687-2691. Epub 2020 Apr 27 doi: 10.1007/s00405-020-05992-y. PMID: 32338297
Grommets in otitis media: a 25-year follow up.
Sederberg-Olsen JF, Sederberg-Olsen N, Holmelund M
Acta Otolaryngol 2018 Dec;138(12):1057-1060. Epub 2019 Jan 31 doi: 10.1080/00016489.2018.1511060. PMID: 30702024
Pretreatment factors affecting traumatic tympanic membrane regeneration therapy using epidermal growth factor.
Lou ZC, Wei H, Lou ZH
Am J Otolaryngol 2018 Nov-Dec;39(6):711-718. Epub 2018 Jul 27 doi: 10.1016/j.amjoto.2018.07.020. PMID: 30078511

Clinical prediction guides

Myringosclerosis as a predictor of the requirement for a permanent pacemaker in patients with drug-related atrioventricular block.
Cosgun MS, Hamur H, Degirmenci H, Coskun R, Karayumak MR, Karabiyik U, Salcan I
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2022 Dec;166(4):412-417. Epub 2022 Jun 21 doi: 10.5507/bp.2022.030. PMID: 35734916
Hearing outcome after tympanoplasty type III.
Tihanyi A, Speck I, Wolff K, Arnold P, Aschendorff A, Arndt S
Eur Arch Otorhinolaryngol 2022 Sep;279(9):4353-4362. Epub 2022 Jan 24 doi: 10.1007/s00405-021-07190-w. PMID: 35072768Free PMC Article
Computer-aided diagnosis of external and middle ear conditions: A machine learning approach.
Viscaino M, Maass JC, Delano PH, Torrente M, Stott C, Auat Cheein F
PLoS One 2020;15(3):e0229226. Epub 2020 Mar 12 doi: 10.1371/journal.pone.0229226. PMID: 32163427Free PMC Article
Pretreatment factors affecting traumatic tympanic membrane regeneration therapy using epidermal growth factor.
Lou ZC, Wei H, Lou ZH
Am J Otolaryngol 2018 Nov-Dec;39(6):711-718. Epub 2018 Jul 27 doi: 10.1016/j.amjoto.2018.07.020. PMID: 30078511
Fat myringoplasty outcome analysis with otoendoscopy: who is the suitable patient?
Konstantinidis I, Malliari H, Tsakiropoulou E, Constantinidis J
Otol Neurotol 2013 Jan;34(1):95-9. doi: 10.1097/MAO.0b013e318278c1e3. PMID: 23202155

Recent systematic reviews

Otitis media with effusion in children.
Williamson I
BMJ Clin Evid 2011 Jan 12;2011 PMID: 21477396Free PMC Article
Otitis media with effusion in children.
Williamson I
BMJ Clin Evid 2007 Aug 1;2007 PMID: 19454116Free PMC Article

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