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Airway Infantile Hemangioma

MedGen UID:
476164
•Concept ID:
C3274531
•
Congenital Abnormality

Definition

A rare infantile hemangioma in the airway, usually in the subglottic area or trachea. It may or may not be associated with cutaneous lesions. It is a potentially life-threatening condition and the infant should be closely monitored for signs of airway disease. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAirway Infantile Hemangioma

Professional guidelines

PubMed

Multicenter Evaluation of the Effectiveness of Systemic Propranolol in the Treatment of Airway Hemangiomas.
Elluru RG, Friess MR, Richter GT, Grimmer JF, Darrow DH, Shin JJ, Perkins JA
Otolaryngol Head Neck Surg 2015 Sep;153(3):452-60. Epub 2015 Jun 29 doi: 10.1177/0194599815591809. PMID: 26124263
Management of airway hemangiomas.
Balakrishnan K, Perkins JA
Expert Rev Respir Med 2010 Aug;4(4):455-62. doi: 10.1586/ers.10.46. PMID: 20658907
Emerging concepts in airway infantile hemangioma assessment and management.
Perkins JA, Duke W, Chen E, Manning S
Otolaryngol Head Neck Surg 2009 Aug;141(2):207-212. doi: 10.1016/j.otohns.2009.04.013. PMID: 19643253

Recent clinical studies

Etiology

Infant in extremis: respiratory failure secondary to lower airway infantile hemangioma.
MacDougall MS, Afzal SY, Freedman MS, Han P
BMC Pediatr 2022 Dec 30;22(1):744. doi: 10.1186/s12887-022-03821-1. PMID: 36581920Free PMC Article
Emerging concepts in airway infantile hemangioma assessment and management.
Perkins JA, Duke W, Chen E, Manning S
Otolaryngol Head Neck Surg 2009 Aug;141(2):207-212. doi: 10.1016/j.otohns.2009.04.013. PMID: 19643253

Diagnosis

Infant in extremis: respiratory failure secondary to lower airway infantile hemangioma.
MacDougall MS, Afzal SY, Freedman MS, Han P
BMC Pediatr 2022 Dec 30;22(1):744. doi: 10.1186/s12887-022-03821-1. PMID: 36581920Free PMC Article
Multicenter Evaluation of the Effectiveness of Systemic Propranolol in the Treatment of Airway Hemangiomas.
Elluru RG, Friess MR, Richter GT, Grimmer JF, Darrow DH, Shin JJ, Perkins JA
Otolaryngol Head Neck Surg 2015 Sep;153(3):452-60. Epub 2015 Jun 29 doi: 10.1177/0194599815591809. PMID: 26124263
Management of airway hemangiomas.
Balakrishnan K, Perkins JA
Expert Rev Respir Med 2010 Aug;4(4):455-62. doi: 10.1586/ers.10.46. PMID: 20658907
Proposal for staging airway hemangiomas.
Perkins JA, Chen EY, Hoffer FA, Manning SC
Otolaryngol Head Neck Surg 2009 Oct;141(4):516-521. doi: 10.1016/j.otohns.2009.06.751. PMID: 19786222
Emerging concepts in airway infantile hemangioma assessment and management.
Perkins JA, Duke W, Chen E, Manning S
Otolaryngol Head Neck Surg 2009 Aug;141(2):207-212. doi: 10.1016/j.otohns.2009.04.013. PMID: 19643253

Therapy

Infant in extremis: respiratory failure secondary to lower airway infantile hemangioma.
MacDougall MS, Afzal SY, Freedman MS, Han P
BMC Pediatr 2022 Dec 30;22(1):744. doi: 10.1186/s12887-022-03821-1. PMID: 36581920Free PMC Article
Multicenter Evaluation of the Effectiveness of Systemic Propranolol in the Treatment of Airway Hemangiomas.
Elluru RG, Friess MR, Richter GT, Grimmer JF, Darrow DH, Shin JJ, Perkins JA
Otolaryngol Head Neck Surg 2015 Sep;153(3):452-60. Epub 2015 Jun 29 doi: 10.1177/0194599815591809. PMID: 26124263
Management of airway hemangiomas.
Balakrishnan K, Perkins JA
Expert Rev Respir Med 2010 Aug;4(4):455-62. doi: 10.1586/ers.10.46. PMID: 20658907
Emerging concepts in airway infantile hemangioma assessment and management.
Perkins JA, Duke W, Chen E, Manning S
Otolaryngol Head Neck Surg 2009 Aug;141(2):207-212. doi: 10.1016/j.otohns.2009.04.013. PMID: 19643253

Prognosis

Management of airway hemangiomas.
Balakrishnan K, Perkins JA
Expert Rev Respir Med 2010 Aug;4(4):455-62. doi: 10.1586/ers.10.46. PMID: 20658907

Clinical prediction guides

Management of airway hemangiomas.
Balakrishnan K, Perkins JA
Expert Rev Respir Med 2010 Aug;4(4):455-62. doi: 10.1586/ers.10.46. PMID: 20658907

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