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Small Intestinal B-Cell Non-Hodgkin Lymphoma

MedGen UID:
474153
•Concept ID:
C3272520
•
Neoplastic Process

Definition

A B-cell non-Hodgkin lymphoma that arises from the small intestine. Representative examples include diffuse large B-cell lymphoma, mucosa-associated lymphoid tissue lymphoma, alpha heavy chain disease/immunoproliferative small intestinal disease, Burkitt lymphoma, follicular lymphoma, and mantle cell lymphoma. [from NCI]

Professional guidelines

PubMed

Review of lymphoma in the duodenum: An update of diagnosis and management.
Iwamuro M, Tanaka T, Okada H
World J Gastroenterol 2023 Mar 28;29(12):1852-1862. doi: 10.3748/wjg.v29.i12.1852. PMID: 37032723Free PMC Article
Idelalisib for treatment of B-cell malignancies.
Do B, Mace M, Rexwinkle A
Am J Health Syst Pharm 2016 Apr 15;73(8):547-55. Epub 2016 Mar 1 doi: 10.2146/ajhp150281. PMID: 26933132
Management of the marginal zone lymphomas.
Vannata B, Stathis A, Zucca E
Cancer Treat Res 2015;165:227-49. doi: 10.1007/978-3-319-13150-4_9. PMID: 25655612

Recent clinical studies

Etiology

B Cell Lymphomas of the GI Tract.
Small S, Barnea Slonim L, Williams C, Karmali R
Curr Gastroenterol Rep 2021 May 8;23(7):9. doi: 10.1007/s11894-021-00811-8. PMID: 33963950
New developments in non-Hodgkin lymphoid malignancies.
Ganapathi KA, Brown LE, Prakash S, Bhargava P
Pathology 2021 Apr;53(3):349-366. Epub 2021 Mar 5 doi: 10.1016/j.pathol.2021.01.002. PMID: 33685720
Gastrointestinal non-Hodgkin lymphomas.
Olszewska-Szopa M, Wróbel T
Adv Clin Exp Med 2019 Aug;28(8):1119-1124. doi: 10.17219/acem/94068. PMID: 31414733
Cryoglobulinemia Vasculitis.
Cacoub P, Comarmond C, Domont F, Savey L, Saadoun D
Am J Med 2015 Sep;128(9):950-5. Epub 2015 Mar 30 doi: 10.1016/j.amjmed.2015.02.017. PMID: 25837517
Gastrointestinal lymphoma.
Isaacson PG
Hum Pathol 1994 Oct;25(10):1020-9. doi: 10.1016/0046-8177(94)90060-4. PMID: 7927306

Diagnosis

Review of lymphoma in the duodenum: An update of diagnosis and management.
Iwamuro M, Tanaka T, Okada H
World J Gastroenterol 2023 Mar 28;29(12):1852-1862. doi: 10.3748/wjg.v29.i12.1852. PMID: 37032723Free PMC Article
New developments in non-Hodgkin lymphoid malignancies.
Ganapathi KA, Brown LE, Prakash S, Bhargava P
Pathology 2021 Apr;53(3):349-366. Epub 2021 Mar 5 doi: 10.1016/j.pathol.2021.01.002. PMID: 33685720
Gastrointestinal non-Hodgkin lymphomas.
Olszewska-Szopa M, Wróbel T
Adv Clin Exp Med 2019 Aug;28(8):1119-1124. doi: 10.17219/acem/94068. PMID: 31414733
Cryoglobulinemia Vasculitis.
Cacoub P, Comarmond C, Domont F, Savey L, Saadoun D
Am J Med 2015 Sep;128(9):950-5. Epub 2015 Mar 30 doi: 10.1016/j.amjmed.2015.02.017. PMID: 25837517
Primary gastrointestinal lymphoma.
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article

Therapy

Extensive small intestinal diffuse large B cell lymphoma.
Liu X, Lv T, Zhang X, Li J
Rev Esp Enferm Dig 2023 May;115(5):267. doi: 10.17235/reed.2022.9100/2022. PMID: 36043558
Idelalisib for treatment of B-cell malignancies.
Do B, Mace M, Rexwinkle A
Am J Health Syst Pharm 2016 Apr 15;73(8):547-55. Epub 2016 Mar 1 doi: 10.2146/ajhp150281. PMID: 26933132
Management of the marginal zone lymphomas.
Vannata B, Stathis A, Zucca E
Cancer Treat Res 2015;165:227-49. doi: 10.1007/978-3-319-13150-4_9. PMID: 25655612
Primary gastrointestinal lymphoma.
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article
Lymphoma of the gastrointestinal tract.
Crump M, Gospodarowicz M, Shepherd FA
Semin Oncol 1999 Jun;26(3):324-37. PMID: 10375089

Prognosis

Dermatitis herpetiformis: a cutaneous manifestation of coeliac disease.
Collin P, Salmi TT, Hervonen K, Kaukinen K, Reunala T
Ann Med 2017 Feb;49(1):23-31. Epub 2016 Dec 14 doi: 10.1080/07853890.2016.1222450. PMID: 27499257
Primary Gastrointestinal Non-Hodgkin's Lymphoma of the Small and Large Intestines: a Systematic Review.
Lightner AL, Shannon E, Gibbons MM, Russell MM
J Gastrointest Surg 2016 Apr;20(4):827-39. Epub 2015 Dec 16 doi: 10.1007/s11605-015-3052-4. PMID: 26676930
Cryoglobulinemia Vasculitis.
Cacoub P, Comarmond C, Domont F, Savey L, Saadoun D
Am J Med 2015 Sep;128(9):950-5. Epub 2015 Mar 30 doi: 10.1016/j.amjmed.2015.02.017. PMID: 25837517
Primary gastrointestinal lymphoma.
Ghimire P, Wu GY, Zhu L
World J Gastroenterol 2011 Feb 14;17(6):697-707. doi: 10.3748/wjg.v17.i6.697. PMID: 21390139Free PMC Article
Gastrointestinal lymphoma.
Isaacson PG
Hum Pathol 1994 Oct;25(10):1020-9. doi: 10.1016/0046-8177(94)90060-4. PMID: 7927306

Clinical prediction guides

Prognostic value of chromosomal translocations in small-bowel diffuse large B-cell lymphoma.
Ikegami K, Nakamura S, Esaki M, Yanai S, Hirahashi M, Oda Y, Takeshita M, Matsumoto T, Kitazono T
Histopathology 2016 Jan;68(2):199-209. Epub 2015 Jun 18 doi: 10.1111/his.12731. PMID: 25953462
Multiple Intestinal Lymphoma.
Mastalier B, Deaconescu V, Elaiah W, Drăghici C, Popp C, Zurac S, Balea M, Tevet M, Botezatu C
Rom J Intern Med 2015 Jan-Mar;53(1):73-8. doi: 10.1515/rjim-2015-0010. PMID: 26076564
Clinical outcome of non-surgical treatment for primary small intestinal lymphoma diagnosed with double-balloon endoscopy.
Kobayashi H, Nagai T, Omine K, Sato K, Ozaki K, Suzuki T, Mori M, Muroi K, Yano T, Yamamoto H, Ozawa K
Leuk Lymphoma 2013 Apr;54(4):731-6. Epub 2012 Sep 28 doi: 10.3109/10428194.2012.725850. PMID: 22946663
Primary intestinal lymphangiectasia (Waldmann's disease).
Vignes S, Bellanger J
Orphanet J Rare Dis 2008 Feb 22;3:5. doi: 10.1186/1750-1172-3-5. PMID: 18294365Free PMC Article
Pathology of intestinal lymphomas.
Foss HD, Stein H
Recent Results Cancer Res 2000;156:33-41. doi: 10.1007/978-3-642-57054-4_5. PMID: 10802861

Recent systematic reviews

Emergency laparotomy for abdominal catastrophes secondary to lymphoma: A systematic review.
Butterworth JW, Brooker-Thompson C, Qureshi YA, Mohammadi B, Dawas K
Eur J Surg Oncol 2024 Jan;50(1):107268. Epub 2023 Nov 19 doi: 10.1016/j.ejso.2023.107268. PMID: 38043361
Treating chronic diarrhea: A systematic review on Immunoproliferative Small Intestinal Disease (IPSID).
Evangelista-Leite D, Affonso Madaloso B, Shouta Yamashita B, Enrico Aloise F, Polito Verdasca L, Lopes de Mello M, Murata Hayashi R, Zimberg Chehter E
PLoS One 2021;16(7):e0253695. Epub 2021 Jul 16 doi: 10.1371/journal.pone.0253695. PMID: 34270561Free PMC Article
Primary Gastrointestinal Non-Hodgkin's Lymphoma of the Small and Large Intestines: a Systematic Review.
Lightner AL, Shannon E, Gibbons MM, Russell MM
J Gastrointest Surg 2016 Apr;20(4):827-39. Epub 2015 Dec 16 doi: 10.1007/s11605-015-3052-4. PMID: 26676930
Composite EBV negative peripheral T-cell lymphoma and diffuse large B-cell lymphoma involving the ileum: a case report and a systematic review of the literature.
Abou-Elella AA, Nifong TP
Leuk Lymphoma 2006 Oct;47(10):2208-17. doi: 10.1080/10428190600763348. PMID: 17071497

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