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Executive Function Disorder

MedGen UID:
473686
•Concept ID:
C2748208
•
Mental or Behavioral Dysfunction
Synonyms: Executive dysfunction; Executive function disorder

Definition

Cognitive, emotional, and behavioral difficulties that often occur in conjunction with frontal lobe disorders, including traumatic injury and dementia. It is also a feature of attention deficit disorder and other non-trauma-induced conditions. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVExecutive Function Disorder

Professional guidelines

PubMed

The Role of Exercise in Management of Mental Health Disorders: An Integrative Review.
Smith PJ, Merwin RM
Annu Rev Med 2021 Jan 27;72:45-62. Epub 2020 Nov 30 doi: 10.1146/annurev-med-060619-022943. PMID: 33256493Free PMC Article
Practical considerations for the evaluation and management of Attention Deficit Hyperactivity Disorder (ADHD) in adults.
Weibel S, Menard O, Ionita A, Boumendjel M, Cabelguen C, Kraemer C, Micoulaud-Franchi JA, Bioulac S, Perroud N, Sauvaget A, Carton L, Gachet M, Lopez R
Encephale 2020 Feb;46(1):30-40. Epub 2019 Oct 11 doi: 10.1016/j.encep.2019.06.005. PMID: 31610922
Diagnosis and Management of Dementia: Review.
Arvanitakis Z, Shah RC, Bennett DA
JAMA 2019 Oct 22;322(16):1589-1599. doi: 10.1001/jama.2019.4782. PMID: 31638686Free PMC Article

Recent clinical studies

Etiology

Utilization of sunglasses: A pilot study to examine a simple test for cognitive dysfunction.
Hoogers SE, Segers-van Rijn JMW, Wirtz PW, de Bruijn SFTM
Clin Neurol Neurosurg 2018 Dec;175:121-123. Epub 2018 Oct 28 doi: 10.1016/j.clineuro.2018.09.040. PMID: 30399602
Use of a verbal fluency measure in understanding and evaluating ADHD as an executive function disorder.
Koziol LF, Stout CE
Percept Mot Skills 1992 Dec;75(3 Pt 2):1187-92. doi: 10.2466/pms.1992.75.3f.1187. PMID: 1484785

Diagnosis

Utilization of sunglasses: A pilot study to examine a simple test for cognitive dysfunction.
Hoogers SE, Segers-van Rijn JMW, Wirtz PW, de Bruijn SFTM
Clin Neurol Neurosurg 2018 Dec;175:121-123. Epub 2018 Oct 28 doi: 10.1016/j.clineuro.2018.09.040. PMID: 30399602
Frontal Tumefactive Demyelinating Lesion Mimicking Glioblastoma Differentiated by Methionine Positron Emission Tomography.
Yasuda S, Yano H, Kimura A, Suzui N, Nakayama N, Shinoda J, Iwama T
World Neurosurg 2018 Nov;119:244-248. Epub 2018 Aug 13 doi: 10.1016/j.wneu.2018.08.027. PMID: 30114544
Attention-Deficit/Hyperactivity Disorder and Successful Completion of Anesthesia Residency: A Case Report.
Fitzsimons MG, Brookman JC, Arnholz SH, Baker K
Acad Med 2016 Feb;91(2):210-4. doi: 10.1097/ACM.0000000000000854. PMID: 26244258
Active and passive executive function disorder subsequent to closed-head injury.
Pachalska M, Kurzbauer H, Talar J, MacQueen BD
Med Sci Monit 2002 Jan;8(1):CS1-9. PMID: 11782680
Use of a verbal fluency measure in understanding and evaluating ADHD as an executive function disorder.
Koziol LF, Stout CE
Percept Mot Skills 1992 Dec;75(3 Pt 2):1187-92. doi: 10.2466/pms.1992.75.3f.1187. PMID: 1484785

Therapy

Plus-minus lid syndrome with ataxia and severe apathy-A rare manifestation of midbrain infarct.
Sheetal S, Thomas R, Kumar AS, Tomy LG
J Postgrad Med 2020 Jul-Sep;66(3):162-164. doi: 10.4103/jpgm.JPGM_709_19. PMID: 32675453Free PMC Article

Prognosis

Utilization of sunglasses: A pilot study to examine a simple test for cognitive dysfunction.
Hoogers SE, Segers-van Rijn JMW, Wirtz PW, de Bruijn SFTM
Clin Neurol Neurosurg 2018 Dec;175:121-123. Epub 2018 Oct 28 doi: 10.1016/j.clineuro.2018.09.040. PMID: 30399602

Clinical prediction guides

Orthostatic hypotension and executive function in older people from the French MERE cohort attending a memory clinic.
Duval GT, Asfar M, Gautier J, Annweiler C
Maturitas 2023 Jul;173:16-19. Epub 2023 May 3 doi: 10.1016/j.maturitas.2023.04.007. PMID: 37182386
Utilization of sunglasses: A pilot study to examine a simple test for cognitive dysfunction.
Hoogers SE, Segers-van Rijn JMW, Wirtz PW, de Bruijn SFTM
Clin Neurol Neurosurg 2018 Dec;175:121-123. Epub 2018 Oct 28 doi: 10.1016/j.clineuro.2018.09.040. PMID: 30399602

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