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Perilobar nephrogenic rest

MedGen UID:
452960
•Concept ID:
C1319017
•
Congenital Abnormality
Synonyms: Nephrogenic rest, perilobar; Perilobar Nephrogenic Rest; Perilobar nephrogenic rests; PLNR-Perilobar nephrogenic rest
SNOMED CT: Nephrogenic rest, perilobar (405935000); PLNR-Perilobar nephrogenic rest (405935000)
 
HPO: HP:0012782

Definition

A type of nephrogenic rest associated with multiple lesions in the periphery of the renal lobe. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPerilobar nephrogenic rest

Professional guidelines

PubMed

Embryonal Origin of Metanephric Adenoma and its Differential Diagnosis.
Sarlos DP, Banyai D, Peterfi L, Szanto A, Kovacs G
Anticancer Res 2018 Dec;38(12):6663-6667. doi: 10.21873/anticanres.13033. PMID: 30504374

Recent clinical studies

Etiology

Nephrogenic rests in Wilms tumors treated with preoperative chemotherapy: The UK SIOP Wilms Tumor 2001 Trial experience.
Vujanić GM, Apps JR, Moroz V, Ceroni F, Williams RD, Sebire NJ, Pritchard-Jones K
Pediatr Blood Cancer 2017 Nov;64(11) Epub 2017 Apr 6 doi: 10.1002/pbc.26547. PMID: 28383760
Loss of heterozygosity at 11p13 and 11p15 in Wilms tumor: a study of 22 cases from India.
Sigamani E, Wari MN, Iyer VK, Agarwala S, Sharma A, Bakhshi S, Dinda A
Pediatr Surg Int 2013 Mar;29(3):223-7. Epub 2013 Jan 5 doi: 10.1007/s00383-012-3254-8. PMID: 23292539
Synchronous bilateral Wilm's tumor with complete radiographic response managed without surgical resection: a report from the National Wilm's Tumor Study 4.
Hamilton TE, Ritchey ML, Argani P, Beckwith JB, Perlman EJ, Cotton CA, Shamberger RC
J Pediatr Surg 2008 Nov;43(11):1982-4. doi: 10.1016/j.jpedsurg.2008.05.037. PMID: 18970928Free PMC Article

Diagnosis

Embryonal Origin of Metanephric Adenoma and its Differential Diagnosis.
Sarlos DP, Banyai D, Peterfi L, Szanto A, Kovacs G
Anticancer Res 2018 Dec;38(12):6663-6667. doi: 10.21873/anticanres.13033. PMID: 30504374
Nephrogenic rests in Wilms tumors treated with preoperative chemotherapy: The UK SIOP Wilms Tumor 2001 Trial experience.
Vujanić GM, Apps JR, Moroz V, Ceroni F, Williams RD, Sebire NJ, Pritchard-Jones K
Pediatr Blood Cancer 2017 Nov;64(11) Epub 2017 Apr 6 doi: 10.1002/pbc.26547. PMID: 28383760

Therapy

Nephrogenic rests in Wilms tumors treated with preoperative chemotherapy: The UK SIOP Wilms Tumor 2001 Trial experience.
Vujanić GM, Apps JR, Moroz V, Ceroni F, Williams RD, Sebire NJ, Pritchard-Jones K
Pediatr Blood Cancer 2017 Nov;64(11) Epub 2017 Apr 6 doi: 10.1002/pbc.26547. PMID: 28383760
Synchronous bilateral Wilm's tumor with complete radiographic response managed without surgical resection: a report from the National Wilm's Tumor Study 4.
Hamilton TE, Ritchey ML, Argani P, Beckwith JB, Perlman EJ, Cotton CA, Shamberger RC
J Pediatr Surg 2008 Nov;43(11):1982-4. doi: 10.1016/j.jpedsurg.2008.05.037. PMID: 18970928Free PMC Article

Prognosis

Nephrogenic rests in Wilms tumors treated with preoperative chemotherapy: The UK SIOP Wilms Tumor 2001 Trial experience.
Vujanić GM, Apps JR, Moroz V, Ceroni F, Williams RD, Sebire NJ, Pritchard-Jones K
Pediatr Blood Cancer 2017 Nov;64(11) Epub 2017 Apr 6 doi: 10.1002/pbc.26547. PMID: 28383760
Synchronous bilateral Wilm's tumor with complete radiographic response managed without surgical resection: a report from the National Wilm's Tumor Study 4.
Hamilton TE, Ritchey ML, Argani P, Beckwith JB, Perlman EJ, Cotton CA, Shamberger RC
J Pediatr Surg 2008 Nov;43(11):1982-4. doi: 10.1016/j.jpedsurg.2008.05.037. PMID: 18970928Free PMC Article

Clinical prediction guides

Nephrogenic rests in Wilms tumors treated with preoperative chemotherapy: The UK SIOP Wilms Tumor 2001 Trial experience.
Vujanić GM, Apps JR, Moroz V, Ceroni F, Williams RD, Sebire NJ, Pritchard-Jones K
Pediatr Blood Cancer 2017 Nov;64(11) Epub 2017 Apr 6 doi: 10.1002/pbc.26547. PMID: 28383760

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