U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Swelling of proximal interphalangeal joints

MedGen UID:
395995
Concept ID:
C1860841
Finding
Synonym: Swelling of innermost hinge joints
 
HPO: HP:0006253

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSwelling of proximal interphalangeal joints

Conditions with this feature

Trichorhinophalangeal dysplasia type I
MedGen UID:
140929
Concept ID:
C0432233
Disease or Syndrome
Trichorhinophalangeal syndrome (TRPS) comprises TRPS I (caused by a heterozygous pathogenic variant in TRPS1) and TRPS II (caused by contiguous gene deletion of TRPS1, RAD21, and EXT1). Both types of TRPS are characterized by distinctive facial features; ectodermal features (fine, sparse, depigmented, and slow growing hair; dystrophic nails; and small breasts); and skeletal findings (short stature; short feet; brachydactyly with ulnar or radial deviation of the fingers; and early, marked hip dysplasia). TRPS II is characterized by multiple osteochondromas (typically first observed clinically on the scapulae and around the elbows and knees between ages 1 month and 6 years) and an increased risk of mild-to-moderate intellectual disability.

Professional guidelines

PubMed

Sandler AB, Scanaliato JP, Dennis T, Gonzalez Trevizo GA, Raiciulescu S, Nesti L, Dunn JC
Hand (N Y) 2022 Sep;17(5):815-824. Epub 2021 Jan 21 doi: 10.1177/1558944720974119. PMID: 33478271Free PMC Article
Haugen IK, Felson DT, Abhishek A, Berenbaum F, Bierma-Zeinstra S, Borgen T, Herrero Beaumont G, Ishimori M, Jonsson H, Kroon FP, Maheu E, Ramonda R, Ritschl V, Stamm TA, van der Heijde D, Wittoek R, Greibrokk E, Smeets W, Kloppenburg M
RMD Open 2020 Jun;6(2) doi: 10.1136/rmdopen-2020-001265. PMID: 32584781Free PMC Article
Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS
Arthritis Rheum 1988 Mar;31(3):315-24. doi: 10.1002/art.1780310302. PMID: 3358796

Recent clinical studies

Etiology

Sandler AB, Scanaliato JP, Dennis T, Gonzalez Trevizo GA, Raiciulescu S, Nesti L, Dunn JC
Hand (N Y) 2022 Sep;17(5):815-824. Epub 2021 Jan 21 doi: 10.1177/1558944720974119. PMID: 33478271Free PMC Article
Steiger CN, Dayer R, Tabard-Fougère A, Ceroni D
J Pediatr 2021 Mar;230:140-145. Epub 2020 Oct 21 doi: 10.1016/j.jpeds.2020.10.038. PMID: 33098842
Spolidoro Paschoal NO, Natour J, Machado FS, Alcântara Veiga de Oliveira H, Vilar Furtado RN
J Ultrasound Med 2017 Feb;36(2):311-319. Epub 2016 Dec 3 doi: 10.7863/ultra.16.01031. PMID: 27914183
Paschos NK, Abuhemoud K, Gantsos A, Mitsionis GI, Georgoulis AD
J Hand Surg Am 2014 Mar;39(3):449-54. Epub 2014 Feb 4 doi: 10.1016/j.jhsa.2013.11.038. PMID: 24503231
Scutellari PN, Orzincolo C
Eur J Radiol 1998 May;27 Suppl 1:S31-8. doi: 10.1016/s0720-048x(98)00040-0. PMID: 9652499

Diagnosis

Childress MA, Olivas J, Crutchfield A
Am Fam Physician 2022 Jun 1;105(6):631-639. PMID: 35704814
Vázquez Fernández R, Maneiro Fernández JR, Cervantes Pérez EC, Mera Varela A
Ir J Med Sci 2021 Aug;190(3):1005-1014. Epub 2020 Oct 1 doi: 10.1007/s11845-020-02378-1. PMID: 33006046
Dallos T, Oppl B, Kovács L, Zwerina J
Curr Rheumatol Rep 2014;16(9):442. doi: 10.1007/s11926-014-0442-7. PMID: 25173950
Grassi W, De Angelis R, Lamanna G, Cervini C
Eur J Radiol 1998 May;27 Suppl 1:S18-24. doi: 10.1016/s0720-048x(98)00038-2. PMID: 9652497
Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS
Arthritis Rheum 1988 Mar;31(3):315-24. doi: 10.1002/art.1780310302. PMID: 3358796

Therapy

Tono T, Kikuchi H, Sawada T, Takeno M, Nagafuchi H, Kirino Y, Tanaka Y, Yamaoka K, Hirohata S
Mod Rheumatol 2022 Oct 15;32(6):1146-1152. doi: 10.1093/mr/roab092. PMID: 34850090
Sandler AB, Scanaliato JP, Dennis T, Gonzalez Trevizo GA, Raiciulescu S, Nesti L, Dunn JC
Hand (N Y) 2022 Sep;17(5):815-824. Epub 2021 Jan 21 doi: 10.1177/1558944720974119. PMID: 33478271Free PMC Article
Li R, Wan Q, Chen P, Mao S, Wang Q, Li X, Yang Y, Dong L
Rheumatol Int 2020 Jul;40(7):1143-1149. Epub 2020 Apr 28 doi: 10.1007/s00296-020-04588-3. PMID: 32347340
Douglass NP, Ladd AL
Hand Clin 2018 May;34(2):289-299. doi: 10.1016/j.hcl.2018.01.001. PMID: 29625646
Paschos NK, Abuhemoud K, Gantsos A, Mitsionis GI, Georgoulis AD
J Hand Surg Am 2014 Mar;39(3):449-54. Epub 2014 Feb 4 doi: 10.1016/j.jhsa.2013.11.038. PMID: 24503231

Prognosis

Anderson RJ, Cui J, Weinblatt ME, Solomon DH, Naik C, Shadick NA
J Clin Rheumatol 2023 Aug 1;29(5):230-234. Epub 2023 May 9 doi: 10.1097/RHU.0000000000001971. PMID: 37158761
Vázquez Fernández R, Maneiro Fernández JR, Cervantes Pérez EC, Mera Varela A
Ir J Med Sci 2021 Aug;190(3):1005-1014. Epub 2020 Oct 1 doi: 10.1007/s11845-020-02378-1. PMID: 33006046
Scutellari PN, Orzincolo C
Eur J Radiol 1998 May;27 Suppl 1:S31-8. doi: 10.1016/s0720-048x(98)00040-0. PMID: 9652499
Grassi W, De Angelis R, Lamanna G, Cervini C
Eur J Radiol 1998 May;27 Suppl 1:S18-24. doi: 10.1016/s0720-048x(98)00038-2. PMID: 9652497
Belhorn LR, Hess EV
Semin Arthritis Rheum 1993 Apr;22(5):298-306. doi: 10.1016/s0049-0172(05)80009-5. PMID: 8511594

Clinical prediction guides

Anderson RJ, Cui J, Weinblatt ME, Solomon DH, Naik C, Shadick NA
J Clin Rheumatol 2023 Aug 1;29(5):230-234. Epub 2023 May 9 doi: 10.1097/RHU.0000000000001971. PMID: 37158761
Tono T, Kikuchi H, Sawada T, Takeno M, Nagafuchi H, Kirino Y, Tanaka Y, Yamaoka K, Hirohata S
Mod Rheumatol 2022 Oct 15;32(6):1146-1152. doi: 10.1093/mr/roab092. PMID: 34850090
Steiger CN, Dayer R, Tabard-Fougère A, Ceroni D
J Pediatr 2021 Mar;230:140-145. Epub 2020 Oct 21 doi: 10.1016/j.jpeds.2020.10.038. PMID: 33098842
Spolidoro Paschoal NO, Natour J, Machado FS, Alcântara Veiga de Oliveira H, Vilar Furtado RN
J Ultrasound Med 2017 Feb;36(2):311-319. Epub 2016 Dec 3 doi: 10.7863/ultra.16.01031. PMID: 27914183
Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS
Arthritis Rheum 1988 Mar;31(3):315-24. doi: 10.1002/art.1780310302. PMID: 3358796

Recent systematic reviews

Sandler AB, Scanaliato JP, Dennis T, Gonzalez Trevizo GA, Raiciulescu S, Nesti L, Dunn JC
Hand (N Y) 2022 Sep;17(5):815-824. Epub 2021 Jan 21 doi: 10.1177/1558944720974119. PMID: 33478271Free PMC Article
Vázquez Fernández R, Maneiro Fernández JR, Cervantes Pérez EC, Mera Varela A
Ir J Med Sci 2021 Aug;190(3):1005-1014. Epub 2020 Oct 1 doi: 10.1007/s11845-020-02378-1. PMID: 33006046

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...