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Adult Grade 3 Meningioma

MedGen UID:
389534
•Concept ID:
C2347749
•
Neoplastic Process
Synonym: Adult Grade III Meningioma

Definition

A grade III meningioma that occurs during adulthood. [from NCI]

Professional guidelines

PubMed

Meningioma: International Consortium on Meningiomas consensus review on scientific advances and treatment paradigms for clinicians, researchers, and patients.
Wang JZ, Landry AP, Raleigh DR, Sahm F, Walsh KM, Goldbrunner R, Yefet LS, Tonn JC, Gui C, Ostrom QT, Barnholtz-Sloan J, Perry A, Ellenbogen Y, Hanemann CO, Jungwirth G, Jenkinson MD, Tabatabai G, Mathiesen TI, McDermott MW, Tatagiba M, la Fougère C, Maas SLN, Galldiks N, Albert NL, Brastianos PK, Ehret F, Minniti G, Lamszus K, Ricklefs FL, Schittenhelm J, Drummond KJ, Dunn IF, Pathmanaban ON, Cohen-Gadol AA, Sulman EP, Tabouret E, Le Rhun E, Mawrin C, Moliterno J, Weller M, Bi WL, Gao A, Yip S, Niyazi M; International Consortium on Meningiomas (ICOM), Aldape K, Wen PY, Short S, Preusser M, Nassiri F, Zadeh G
Neuro Oncol 2024 Oct 3;26(10):1742-1780. doi: 10.1093/neuonc/noae082. PMID: 38695575Free PMC Article
Tamoxifen. A treatment for meningioma?
Champeaux-Depond C, Weller J
Cancer Treat Res Commun 2021;27:100343. Epub 2021 Feb 24 doi: 10.1016/j.ctarc.2021.100343. PMID: 33647870
The genetic basis of intradural spinal tumors and its impact on clinical treatment.
Karsy M, Guan J, Sivakumar W, Neil JA, Schmidt MH, Mahan MA
Neurosurg Focus 2015 Aug;39(2):E3. doi: 10.3171/2015.5.FOCUS15143. PMID: 26235020

Recent clinical studies

Etiology

Spinal meningioma: clinical profile and outcome of surgical management.
Oyemolade TA, Adeolu AA, Malomo AO, Shokunbi MT, Salami AA
Pan Afr Med J 2022;43:44. Epub 2022 Sep 27 doi: 10.11604/pamj.2022.43.44.19808. PMID: 36523272Free PMC Article
A molecularly integrated grade for meningioma.
Driver J, Hoffman SE, Tavakol S, Woodward E, Maury EA, Bhave V, Greenwald NF, Nassiri F, Aldape K, Zadeh G, Choudhury A, Vasudevan HN, Magill ST, Raleigh DR, Abedalthagafi M, Aizer AA, Alexander BM, Ligon KL, Reardon DA, Wen PY, Al-Mefty O, Ligon AH, Dubuc AM, Beroukhim R, Claus EB, Dunn IF, Santagata S, Bi WL
Neuro Oncol 2022 May 4;24(5):796-808. doi: 10.1093/neuonc/noab213. PMID: 34508644Free PMC Article
Meningioma: A Pathology Perspective.
Toland A, Huntoon K, Dahiya SM
Neurosurgery 2021 Jun 15;89(1):11-21. doi: 10.1093/neuros/nyab001. PMID: 33588439
High-risk Meningioma: Initial Outcomes From NRG Oncology/RTOG 0539.
Rogers CL, Won M, Vogelbaum MA, Perry A, Ashby LS, Modi JM, Alleman AM, Galvin J, Fogh SE, Youssef E, Deb N, Kwok Y, Robinson CG, Shu HK, Fisher BJ, Panet-Raymond V, McMillan WG, de Groot JF, Zhang P, Mehta MP
Int J Radiat Oncol Biol Phys 2020 Mar 15;106(4):790-799. Epub 2019 Nov 29 doi: 10.1016/j.ijrobp.2019.11.028. PMID: 31786276Free PMC Article
Proton therapy for atypical meningiomas.
McDonald MW, Plankenhorn DA, McMullen KP, Henderson MA, Dropcho EJ, Shah MV, Cohen-Gadol AA
J Neurooncol 2015 May;123(1):123-8. Epub 2015 Apr 10 doi: 10.1007/s11060-015-1770-9. PMID: 25859843

Diagnosis

Adjuvant Stereotactic Radiosurgery for Clear Cell Meningiomas.
Wei Z, Jose SG, Agarwal P, Worrell S, Kulich S, Donohue JK, Deng H, Hadjipanayis CG, Niranjan A, Lunsford LD
World Neurosurg 2024 Apr;184:e784-e793. Epub 2024 Feb 13 doi: 10.1016/j.wneu.2024.02.043. PMID: 38360207
A rare encounter: Comprehensive case review of myxoid meningiomas with a representative case.
Talbot NC, Proctor C, Takei H, Toms JB
Neuropathology 2024 Jun;44(3):230-235. Epub 2023 Nov 12 doi: 10.1111/neup.12955. PMID: 37953487
Functional outcome after surgical treatment of spinal meningioma.
Hohenberger C, Gugg C, Schmidt NO, Zeman F, Schebesch KM
J Clin Neurosci 2020 Jul;77:62-66. Epub 2020 May 12 doi: 10.1016/j.jocn.2020.05.042. PMID: 32409209
Everolimus and Octreotide for Patients with Recurrent Meningioma: Results from the Phase II CEVOREM Trial.
Graillon T, Sanson M, Campello C, Idbaih A, Peyre M, Peyrière H, Basset N, Autran D, Roche C, Kalamarides M, Roche PH, Fuentes S, Tabouret E, Barrie M, Cohen A, Honoré S, Boucekine M, Baumstarck K, Figarella-Branger D, Barlier A, Dufour H, Chinot OL
Clin Cancer Res 2020 Feb 1;26(3):552-557. Epub 2020 Jan 22 doi: 10.1158/1078-0432.CCR-19-2109. PMID: 31969329
Intermediate-risk meningioma: initial outcomes from NRG Oncology RTOG 0539.
Rogers L, Zhang P, Vogelbaum MA, Perry A, Ashby LS, Modi JM, Alleman AM, Galvin J, Brachman D, Jenrette JM, De Groot J, Bovi JA, Werner-Wasik M, Knisely JPS, Mehta MP
J Neurosurg 2018 Jul;129(1):35-47. Epub 2017 Oct 6 doi: 10.3171/2016.11.JNS161170. PMID: 28984517Free PMC Article

Therapy

Glioblastoma and Other Primary Brain Malignancies in Adults: A Review.
Schaff LR, Mellinghoff IK
JAMA 2023 Feb 21;329(7):574-587. doi: 10.1001/jama.2023.0023. PMID: 36809318Free PMC Article
A molecularly integrated grade for meningioma.
Driver J, Hoffman SE, Tavakol S, Woodward E, Maury EA, Bhave V, Greenwald NF, Nassiri F, Aldape K, Zadeh G, Choudhury A, Vasudevan HN, Magill ST, Raleigh DR, Abedalthagafi M, Aizer AA, Alexander BM, Ligon KL, Reardon DA, Wen PY, Al-Mefty O, Ligon AH, Dubuc AM, Beroukhim R, Claus EB, Dunn IF, Santagata S, Bi WL
Neuro Oncol 2022 May 4;24(5):796-808. doi: 10.1093/neuonc/noab213. PMID: 34508644Free PMC Article
Can Ophthalmologic Examination Predict Abducens Nerve Recovery After Endoscopic Skull Base Surgery?
Whelan RL, McDowell M, Chou C, Medsinge A, Lee J, Gardner PA, Snyderman CH, Stefko ST, Wang EW
Laryngoscope 2021 Mar;131(3):513-517. Epub 2020 Aug 18 doi: 10.1002/lary.29008. PMID: 32809233
High-risk Meningioma: Initial Outcomes From NRG Oncology/RTOG 0539.
Rogers CL, Won M, Vogelbaum MA, Perry A, Ashby LS, Modi JM, Alleman AM, Galvin J, Fogh SE, Youssef E, Deb N, Kwok Y, Robinson CG, Shu HK, Fisher BJ, Panet-Raymond V, McMillan WG, de Groot JF, Zhang P, Mehta MP
Int J Radiat Oncol Biol Phys 2020 Mar 15;106(4):790-799. Epub 2019 Nov 29 doi: 10.1016/j.ijrobp.2019.11.028. PMID: 31786276Free PMC Article
Temozolomide for treatment-resistant recurrent meningioma.
Chamberlain MC, Tsao-Wei DD, Groshen S
Neurology 2004 Apr 13;62(7):1210-2. doi: 10.1212/01.wnl.0000118300.82017.f4. PMID: 15079029

Prognosis

Adjuvant Stereotactic Radiosurgery for Clear Cell Meningiomas.
Wei Z, Jose SG, Agarwal P, Worrell S, Kulich S, Donohue JK, Deng H, Hadjipanayis CG, Niranjan A, Lunsford LD
World Neurosurg 2024 Apr;184:e784-e793. Epub 2024 Feb 13 doi: 10.1016/j.wneu.2024.02.043. PMID: 38360207
A molecularly integrated grade for meningioma.
Driver J, Hoffman SE, Tavakol S, Woodward E, Maury EA, Bhave V, Greenwald NF, Nassiri F, Aldape K, Zadeh G, Choudhury A, Vasudevan HN, Magill ST, Raleigh DR, Abedalthagafi M, Aizer AA, Alexander BM, Ligon KL, Reardon DA, Wen PY, Al-Mefty O, Ligon AH, Dubuc AM, Beroukhim R, Claus EB, Dunn IF, Santagata S, Bi WL
Neuro Oncol 2022 May 4;24(5):796-808. doi: 10.1093/neuonc/noab213. PMID: 34508644Free PMC Article
Meningioma: A Pathology Perspective.
Toland A, Huntoon K, Dahiya SM
Neurosurgery 2021 Jun 15;89(1):11-21. doi: 10.1093/neuros/nyab001. PMID: 33588439
Genomic landscape of intracranial meningiomas.
Bi WL, Abedalthagafi M, Horowitz P, Agarwalla PK, Mei Y, Aizer AA, Brewster R, Dunn GP, Al-Mefty O, Alexander BM, Santagata S, Beroukhim R, Dunn IF
J Neurosurg 2016 Sep;125(3):525-35. Epub 2016 Jan 15 doi: 10.3171/2015.6.JNS15591. PMID: 26771848
Proton therapy for atypical meningiomas.
McDonald MW, Plankenhorn DA, McMullen KP, Henderson MA, Dropcho EJ, Shah MV, Cohen-Gadol AA
J Neurooncol 2015 May;123(1):123-8. Epub 2015 Apr 10 doi: 10.1007/s11060-015-1770-9. PMID: 25859843

Clinical prediction guides

A molecularly integrated grade for meningioma.
Driver J, Hoffman SE, Tavakol S, Woodward E, Maury EA, Bhave V, Greenwald NF, Nassiri F, Aldape K, Zadeh G, Choudhury A, Vasudevan HN, Magill ST, Raleigh DR, Abedalthagafi M, Aizer AA, Alexander BM, Ligon KL, Reardon DA, Wen PY, Al-Mefty O, Ligon AH, Dubuc AM, Beroukhim R, Claus EB, Dunn IF, Santagata S, Bi WL
Neuro Oncol 2022 May 4;24(5):796-808. doi: 10.1093/neuonc/noab213. PMID: 34508644Free PMC Article
Functional outcome after surgical treatment of spinal meningioma.
Hohenberger C, Gugg C, Schmidt NO, Zeman F, Schebesch KM
J Clin Neurosci 2020 Jul;77:62-66. Epub 2020 May 12 doi: 10.1016/j.jocn.2020.05.042. PMID: 32409209
Genomic landscape of intracranial meningiomas.
Bi WL, Abedalthagafi M, Horowitz P, Agarwalla PK, Mei Y, Aizer AA, Brewster R, Dunn GP, Al-Mefty O, Alexander BM, Santagata S, Beroukhim R, Dunn IF
J Neurosurg 2016 Sep;125(3):525-35. Epub 2016 Jan 15 doi: 10.3171/2015.6.JNS15591. PMID: 26771848
MEG localization of spike sources in human patients with brain tumors.
Birbilis T, Anninos P, Seimenis I, Adamopoulos A, Kotini A
J Integr Neurosci 2014 Sep;13(3):519-28. Epub 2014 Jun 2 doi: 10.1142/S0219635214500150. PMID: 25164355
Stereotactic radiosurgery for WHO grade I meningiomas.
Sheehan JP, Williams BJ, Yen CP
J Neurooncol 2010 Sep;99(3):407-16. Epub 2010 Aug 24 doi: 10.1007/s11060-010-0363-x. PMID: 20734218

Recent systematic reviews

A systematic review of extraneural meningioma metastasis: timing, evolution and outlook.
Watanabe G, Young K, Rauber E, Khan MF, Suzuki R, Riestenberg R, Umana GE, Palmisciano P
J Neurooncol 2024 Jun;168(2):187-196. Epub 2024 Mar 26 doi: 10.1007/s11060-024-04659-6. PMID: 38530549
Primary intracranial papillary meningioma: Analysis of factors of prognosis and systematic review.
Zhang GS, Zhang YY, He F, Ou ML, Wang LK, Liao L, Ran RJ, Xiang HH, Chen JH, Wang SJ
J Clin Neurosci 2021 Sep;91:118-124. Epub 2021 Jul 5 doi: 10.1016/j.jocn.2021.06.025. PMID: 34373015
Foramen magnum meningiomas: a systematic review and meta-analysis.
Paun L, Gondar R, Borrelli P, Meling TR
Neurosurg Rev 2021 Oct;44(5):2583-2596. Epub 2021 Jan 28 doi: 10.1007/s10143-021-01478-5. PMID: 33507444Free PMC Article
Synchronous Tumors of the Cerebellopontine Angle.
Graffeo CS, Perry A, Copeland WR 3rd, Giannini C, Neff BA, Driscoll CL, Link MJ
World Neurosurg 2017 Feb;98:632-643. Epub 2016 Nov 12 doi: 10.1016/j.wneu.2016.11.002. PMID: 27836701
Recurrence-associated chromosomal anomalies in meningiomas: Single-institution study and a systematic review with meta-analysis.
Och W, Szmuda T, Sikorska B, Springer J, Jaskólski D, Zakrzewska M, Liberski PP
Neurol Neurochir Pol 2016 Nov-Dec;50(6):439-448. Epub 2016 Aug 20 doi: 10.1016/j.pjnns.2016.08.003. PMID: 27575681

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