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Recurrent Spinal Cord Neoplasm

MedGen UID:
378770
•Concept ID:
C2347917
•
Neoplastic Process
Synonym: Recurrent Spinal Cord Tumor

Definition

The reemergence of a spinal cord neoplasm after a period of remission. [from NCI]

Professional guidelines

PubMed

Primary central nervous system lymphoma.
Ferreri AJM, Calimeri T, Cwynarski K, Dietrich J, Grommes C, Hoang-Xuan K, Hu LS, Illerhaus G, Nayak L, Ponzoni M, Batchelor TT
Nat Rev Dis Primers 2023 Jun 15;9(1):29. doi: 10.1038/s41572-023-00439-0. PMID: 37322012Free PMC Article
Spinal Tumors: Diagnosis and Treatment.
Goodwin ML, Buchowski JM, Schwab JH, Sciubba DM
J Am Acad Orthop Surg 2022 Sep 1;30(17):e1106-e1121. doi: 10.5435/JAAOS-D-21-00710. PMID: 35984082
Intradural spinal tumors in adults-update on management and outcome.
Ottenhausen M, Ntoulias G, Bodhinayake I, Ruppert FH, Schreiber S, Förschler A, Boockvar JA, Jödicke A
Neurosurg Rev 2019 Jun;42(2):371-388. Epub 2018 Feb 17 doi: 10.1007/s10143-018-0957-x. PMID: 29455369

Recent clinical studies

Etiology

Spinal Tumors: Diagnosis and Treatment.
Goodwin ML, Buchowski JM, Schwab JH, Sciubba DM
J Am Acad Orthop Surg 2022 Sep 1;30(17):e1106-e1121. doi: 10.5435/JAAOS-D-21-00710. PMID: 35984082
MRI characteristics and resectability in spinal cord glioma.
Seaman SC, Bathla G, Park BJ, Woodroffe RW, Smith M, Menezes AH, Noeller J, Yamaguchi S, Hitchon PW
Clin Neurol Neurosurg 2021 Jan;200:106321. Epub 2020 Oct 19 doi: 10.1016/j.clineuro.2020.106321. PMID: 33268194
Spinal Cord Tumor Microenvironment.
Rauschenbach L
Adv Exp Med Biol 2020;1226:97-109. doi: 10.1007/978-3-030-36214-0_8. PMID: 32030679
Pediatric Spinal Ependymomas.
Sofuoğlu ÖE, Abdallah A
Med Sci Monit 2018 Oct 5;24:7072-7089. doi: 10.12659/MSM.910447. PMID: 30287802Free PMC Article
Ependymoma.
Reni M, Gatta G, Mazza E, Vecht C
Crit Rev Oncol Hematol 2007 Jul;63(1):81-9. Epub 2007 May 4 doi: 10.1016/j.critrevonc.2007.03.004. PMID: 17482475

Diagnosis

Malignant Spinal Tumors.
Noureldine MHA, Shimony N, Jallo GI
Adv Exp Med Biol 2023;1405:565-581. doi: 10.1007/978-3-031-23705-8_22. PMID: 37452954
Spinal Tumors: Diagnosis and Treatment.
Goodwin ML, Buchowski JM, Schwab JH, Sciubba DM
J Am Acad Orthop Surg 2022 Sep 1;30(17):e1106-e1121. doi: 10.5435/JAAOS-D-21-00710. PMID: 35984082
Spinal schwannoma causes acute subarachnoid haemorrhage: A case report and literature review.
Chen P, Guo Y, Huang R, Xiao J, Cheng Z
Neurochirurgie 2021 Sep;67(5):495-499. Epub 2021 Jan 12 doi: 10.1016/j.neuchi.2020.12.002. PMID: 33450272
Intradural spinal tumors in adults-update on management and outcome.
Ottenhausen M, Ntoulias G, Bodhinayake I, Ruppert FH, Schreiber S, Förschler A, Boockvar JA, Jödicke A
Neurosurg Rev 2019 Jun;42(2):371-388. Epub 2018 Feb 17 doi: 10.1007/s10143-018-0957-x. PMID: 29455369
Ependymoma.
Reni M, Gatta G, Mazza E, Vecht C
Crit Rev Oncol Hematol 2007 Jul;63(1):81-9. Epub 2007 May 4 doi: 10.1016/j.critrevonc.2007.03.004. PMID: 17482475

Therapy

Outcomes Of Intraoperative Radiotherapy (Iort) For Spinal Tumours.
Ebad Ali SM, Abbasi AN, Zahoor N
J Ayub Med Coll Abbottabad 2022 Jan-Mar;34(1):183-191. doi: 10.55519/JAMC-01-9230. PMID: 35466650
Primary Central Nervous System Lymphomas.
Chukwueke U, Grommes C, Nayak L
Hematol Oncol Clin North Am 2022 Feb;36(1):147-159. doi: 10.1016/j.hoc.2021.09.004. PMID: 34801161
Primary central nervous system lymphoma.
Schaff LR, Grommes C
Blood 2022 Sep 1;140(9):971-979. doi: 10.1182/blood.2020008377. PMID: 34699590Free PMC Article
A phase II study of dose-dense temozolomide and lapatinib for recurrent low-grade and anaplastic supratentorial, infratentorial, and spinal cord ependymoma.
Gilbert MR, Yuan Y, Wu J, Mendoza T, Vera E, Omuro A, Lieberman F, Robins HI, Gerstner ER, Wu J, Wen PY, Mikkelsen T, Aldape K, Armstrong TS
Neuro Oncol 2021 Mar 25;23(3):468-477. doi: 10.1093/neuonc/noaa240. PMID: 33085768Free PMC Article
Nivolumab versus chemotherapy in patients with advanced oesophageal squamous cell carcinoma refractory or intolerant to previous chemotherapy (ATTRACTION-3): a multicentre, randomised, open-label, phase 3 trial.
Kato K, Cho BC, Takahashi M, Okada M, Lin CY, Chin K, Kadowaki S, Ahn MJ, Hamamoto Y, Doki Y, Yen CC, Kubota Y, Kim SB, Hsu CH, Holtved E, Xynos I, Kodani M, Kitagawa Y
Lancet Oncol 2019 Nov;20(11):1506-1517. Epub 2019 Sep 30 doi: 10.1016/S1470-2045(19)30626-6. PMID: 31582355

Prognosis

Intramedullary cervical spinal cord teratoma.
Wang L, Li T, Gong M, Xing F, Li L, Xiao R, Guan Q
Medicine (Baltimore) 2020 May;99(18):e20107. doi: 10.1097/MD.0000000000020107. PMID: 32358400Free PMC Article
Spinal Pilomyxoid Astrocytoma.
Almubarak AO, Ulhaq A, BinDahmash A, Al Shail E
Pediatr Neurosurg 2019;54(6):399-404. Epub 2019 Oct 8 doi: 10.1159/000502615. PMID: 31593949
Pediatric Spinal Ependymomas.
Sofuoğlu ÖE, Abdallah A
Med Sci Monit 2018 Oct 5;24:7072-7089. doi: 10.12659/MSM.910447. PMID: 30287802Free PMC Article
Literature Review of Spinal Cord Glioblastoma.
Timmons JJ, Zhang K, Fong J, Lok E, Swanson KD, Gautam S, Wong ET
Am J Clin Oncol 2018 Dec;41(12):1281-1287. doi: 10.1097/COC.0000000000000434. PMID: 29528867
Ependymoma.
Reni M, Gatta G, Mazza E, Vecht C
Crit Rev Oncol Hematol 2007 Jul;63(1):81-9. Epub 2007 May 4 doi: 10.1016/j.critrevonc.2007.03.004. PMID: 17482475

Clinical prediction guides

Outcomes Of Intraoperative Radiotherapy (Iort) For Spinal Tumours.
Ebad Ali SM, Abbasi AN, Zahoor N
J Ayub Med Coll Abbottabad 2022 Jan-Mar;34(1):183-191. doi: 10.55519/JAMC-01-9230. PMID: 35466650
MRI characteristics and resectability in spinal cord glioma.
Seaman SC, Bathla G, Park BJ, Woodroffe RW, Smith M, Menezes AH, Noeller J, Yamaguchi S, Hitchon PW
Clin Neurol Neurosurg 2021 Jan;200:106321. Epub 2020 Oct 19 doi: 10.1016/j.clineuro.2020.106321. PMID: 33268194
Central Nervous System Lymphomas.
Grommes C
Continuum (Minneap Minn) 2020 Dec;26(6):1476-1494. doi: 10.1212/CON.0000000000000936. PMID: 33273169
Clinical, Radiologic, and Prognostic Features of Myelitis Associated With Myelin Oligodendrocyte Glycoprotein Autoantibody.
Dubey D, Pittock SJ, Krecke KN, Morris PP, Sechi E, Zalewski NL, Weinshenker BG, Shosha E, Lucchinetti CF, Fryer JP, Lopez-Chiriboga AS, Chen JC, Jitprapaikulsan J, McKeon A, Gadoth A, Keegan BM, Tillema JM, Naddaf E, Patterson MC, Messacar K, Tyler KL, Flanagan EP
JAMA Neurol 2019 Mar 1;76(3):301-309. doi: 10.1001/jamaneurol.2018.4053. PMID: 30575890Free PMC Article
Literature Review of Spinal Cord Glioblastoma.
Timmons JJ, Zhang K, Fong J, Lok E, Swanson KD, Gautam S, Wong ET
Am J Clin Oncol 2018 Dec;41(12):1281-1287. doi: 10.1097/COC.0000000000000434. PMID: 29528867

Recent systematic reviews

Spinal Ganglioneuroma: A Systematic Review of the Literature.
Yousefi O, Saghebdoust S, Abdollahifard S, Motlagh MA, Farrokhi MR, Motiei-Langroudi R, Mousavi SR
World Neurosurg 2023 Dec;180:163-168.e7. Epub 2023 Sep 1 doi: 10.1016/j.wneu.2023.08.057. PMID: 37659751
Calcified spinal meningiomas: a systematic review of clinical characteristics, treatment strategies, and outcomes.
Shah DS, Reddy RV, Doğruel Y, Asfour MZ, Pour-Rashidi A, Haider AS, Sharma M, Aoun SG, Umana GE, Palmisciano P
J Neurooncol 2023 Apr;162(2):295-305. Epub 2023 Mar 17 doi: 10.1007/s11060-023-04291-w. PMID: 36932228
Clinical Characteristics, Management, and Outcomes of Intramedullary Spinal Cord Ependymomas in Adults: A Systematic Review.
Farooqi S, Tebha SS, Qamar MA, Singh S, Alfawares Y, Ramanathan V, Haider AS, Ferini G, Sharma M, Umana GE, Aoun SG, Palmisciano P
World Neurosurg 2023 May;173:237-250.e8. Epub 2023 Feb 28 doi: 10.1016/j.wneu.2023.02.098. PMID: 36858296
Novel Clinical Insights into Spinal Hemangioblastoma in Adults: A Systematic Review.
Jankovic D, Hanissian A, Rotim K, Splavski B, Arnautovic KI
World Neurosurg 2022 Feb;158:1-10. Epub 2021 Oct 21 doi: 10.1016/j.wneu.2021.10.105. PMID: 34687932
Intramedullary cervical spinal cord teratoma.
Wang L, Li T, Gong M, Xing F, Li L, Xiao R, Guan Q
Medicine (Baltimore) 2020 May;99(18):e20107. doi: 10.1097/MD.0000000000020107. PMID: 32358400Free PMC Article

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