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Cancer Progression

MedGen UID:
364930
Concept ID:
C1947901
Pathologic Function
Synonym: Cancer Disease Progression

Definition

A pathologic process in which alterations at the molecular level result in a more aggressive cytologic and phenotypic profile and clinical course of a malignant neoplasm. [from NCI]

Professional guidelines

PubMed

Quail DF, Amulic B, Aziz M, Barnes BJ, Eruslanov E, Fridlender ZG, Goodridge HS, Granot Z, Hidalgo A, Huttenlocher A, Kaplan MJ, Malanchi I, Merghoub T, Meylan E, Mittal V, Pittet MJ, Rubio-Ponce A, Udalova IA, van den Berg TK, Wagner DD, Wang P, Zychlinsky A, de Visser KE, Egeblad M, Kubes P
J Exp Med 2022 Jun 6;219(6) Epub 2022 May 6 doi: 10.1084/jem.20220011. PMID: 35522219Free PMC Article
Hsu CC, Peng D, Cai Z, Lin HK
Semin Cancer Biol 2022 Oct;85:52-68. Epub 2021 Apr 18 doi: 10.1016/j.semcancer.2021.04.006. PMID: 33862221Free PMC Article
Hojman P, Gehl J, Christensen JF, Pedersen BK
Cell Metab 2018 Jan 9;27(1):10-21. Epub 2017 Oct 19 doi: 10.1016/j.cmet.2017.09.015. PMID: 29056514

Recent clinical studies

Etiology

Chen J, Liu X, Zou Y, Gong J, Ge Z, Lin X, Zhang W, Huang H, Zhao J, Saw PE, Lu Y, Hu H, Song E
Proc Natl Acad Sci U S A 2024 May 14;121(20):e2306776121. Epub 2024 May 6 doi: 10.1073/pnas.2306776121. PMID: 38709933Free PMC Article
Liu J, Fan H, Liang X, Chen Y
Biomed Pharmacother 2023 Dec 31;169:115897. Epub 2023 Nov 17 doi: 10.1016/j.biopha.2023.115897. PMID: 37981459
Leandro-García LJ, Landa I
Endocrinology 2023 Aug 1;164(9) doi: 10.1210/endocr/bqad118. PMID: 37503738Free PMC Article
Kakavandi E, Shahbahrami R, Goudarzi H, Eslami G, Faghihloo E
J Cell Biochem 2018 Mar;119(3):2484-2491. Epub 2017 Sep 12 doi: 10.1002/jcb.26363. PMID: 28836703
Davidoff AM
Semin Pediatr Surg 2010 Aug;19(3):225-33. doi: 10.1053/j.sempedsurg.2010.03.007. PMID: 20610196Free PMC Article

Diagnosis

Yokoyama S, Matsuo K, Tanimoto A
Methods Mol Biol 2024;2763:259-268. doi: 10.1007/978-1-0716-3670-1_22. PMID: 38347417
Jin Y, Xing J, Xu K, Liu D, Zhuo Y
Front Immunol 2022;13:1025218. Epub 2022 Oct 6 doi: 10.3389/fimmu.2022.1025218. PMID: 36275738Free PMC Article
Wang B, Wang M, Ao D, Wei X
Biochim Biophys Acta Rev Cancer 2022 Sep;1877(5):188799. Epub 2022 Sep 11 doi: 10.1016/j.bbcan.2022.188799. PMID: 36103908
Chen Y, McAndrews KM, Kalluri R
Nat Rev Clin Oncol 2021 Dec;18(12):792-804. Epub 2021 Sep 6 doi: 10.1038/s41571-021-00546-5. PMID: 34489603Free PMC Article
Xu X, Zhang M, Xu F, Jiang S
Mol Cancer 2020 Nov 24;19(1):165. doi: 10.1186/s12943-020-01276-5. PMID: 33234169Free PMC Article

Therapy

Zhang H, Yue X, Chen Z, Liu C, Wu W, Zhang N, Liu Z, Yang L, Jiang Q, Cheng Q, Luo P, Liu G
Mol Cancer 2023 Oct 2;22(1):159. doi: 10.1186/s12943-023-01860-5. PMID: 37784082Free PMC Article
Olejarz W, Kubiak-Tomaszewska G, Chrzanowska A, Lorenc T
Int J Mol Sci 2020 Aug 14;21(16) doi: 10.3390/ijms21165840. PMID: 32823989Free PMC Article
Malo-Manso A, Raigon-Ponferrada A, Diaz-Crespo J, Escalona-Belmonte JJ, Cruz-Mañas J, Guerrero-Orriach JL
Curr Pharm Des 2019;25(28):3011-3019. doi: 10.2174/1381612825666190705183754. PMID: 31298153
Hughes VS, Siemann DW
Trends Cancer 2018 Feb;4(2):94-97. doi: 10.1016/j.trecan.2017.11.009. PMID: 29458966Free PMC Article
Goel HL, Li J, Kogan S, Languino LR
Endocr Relat Cancer 2008 Sep;15(3):657-64. Epub 2008 Jun 4 doi: 10.1677/ERC-08-0019. PMID: 18524948Free PMC Article

Prognosis

Kinugawa T, Wada T, Manabe Y, Sato F, Tanaka S
Radiat Prot Dosimetry 2022 Sep 9;198(13-15):1160-1164. doi: 10.1093/rpd/ncac087. PMID: 36083765
Valpione S, Mundra PA, Galvani E, Campana LG, Lorigan P, De Rosa F, Gupta A, Weightman J, Mills S, Dhomen N, Marais R
Nat Commun 2021 Jul 2;12(1):4098. doi: 10.1038/s41467-021-24343-x. PMID: 34215730Free PMC Article
Wang M, Jiang X
Cancer Biol Ther 2019;20(2):130-137. Epub 2018 Sep 27 doi: 10.1080/15384047.2018.1523854. PMID: 30261153Free PMC Article
Bazhenova L, Newton P, Mason J, Bethel K, Nieva J, Kuhn P
J Thorac Oncol 2014 Apr;9(4):442-6. doi: 10.1097/JTO.0000000000000133. PMID: 24736064Free PMC Article
Davidoff AM
Semin Pediatr Surg 2010 Aug;19(3):225-33. doi: 10.1053/j.sempedsurg.2010.03.007. PMID: 20610196Free PMC Article

Clinical prediction guides

Zhang T, Zhao F, Lin Y, Liu M, Zhou H, Cui F, Jin Y, Chen L, Sheng X
Theranostics 2024;14(3):1065-1080. Epub 2024 Jan 1 doi: 10.7150/thno.92336. PMID: 38250042Free PMC Article
Huang X, Liu Y, Qian C, Shen Q, Wu M, Zhu B, Feng Y
J Transl Med 2023 Jul 17;21(1):474. doi: 10.1186/s12967-023-04333-x. PMID: 37461041Free PMC Article
Vishwakarma GK, Bhattacharjee A, Banerjee S, Liquet B
Stat Med 2020 Dec 10;39(28):4201-4217. Epub 2020 Aug 25 doi: 10.1002/sim.8720. PMID: 32844489
Bruni D, Angell HK, Galon J
Nat Rev Cancer 2020 Nov;20(11):662-680. Epub 2020 Aug 4 doi: 10.1038/s41568-020-0285-7. PMID: 32753728
Templeton AJ, McNamara MG, Šeruga B, Vera-Badillo FE, Aneja P, Ocaña A, Leibowitz-Amit R, Sonpavde G, Knox JJ, Tran B, Tannock IF, Amir E
J Natl Cancer Inst 2014 Jun;106(6):dju124. Epub 2014 May 29 doi: 10.1093/jnci/dju124. PMID: 24875653

Recent systematic reviews

Yang K, Wang X, Song C, He Z, Wang R, Xu Y, Jiang G, Wan Y, Mei J, Mao W
Theranostics 2023;13(6):1774-1808. Epub 2023 Mar 13 doi: 10.7150/thno.82920. PMID: 37064872Free PMC Article
Mishan MA, Khazeei Tabari MA, Mahrooz A, Bagheri A
Eur J Cancer Prev 2021 Sep 1;30(5):413-421. doi: 10.1097/CEJ.0000000000000645. PMID: 33720053
Wang X, Wang N, Zhong L, Wang S, Zheng Y, Yang B, Zhang J, Lin Y, Wang Z
Mol Psychiatry 2020 Dec;25(12):3186-3197. Epub 2020 Aug 20 doi: 10.1038/s41380-020-00865-6. PMID: 32820237Free PMC Article
Wang K, Wang RL, Liu JJ, Zhou J, Li X, Hu WW, Jiang WJ, Hao NB
Medicine (Baltimore) 2018 Aug;97(35):e11794. doi: 10.1097/MD.0000000000011794. PMID: 30170373Free PMC Article
Templeton AJ, McNamara MG, Šeruga B, Vera-Badillo FE, Aneja P, Ocaña A, Leibowitz-Amit R, Sonpavde G, Knox JJ, Tran B, Tannock IF, Amir E
J Natl Cancer Inst 2014 Jun;106(6):dju124. Epub 2014 May 29 doi: 10.1093/jnci/dju124. PMID: 24875653

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