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Metatypical basal cell carcinoma

MedGen UID:
362831
•Concept ID:
C1883040
•
Neoplastic Process
Synonym: Skin Metatypical Carcinoma
 
Monarch Initiative: MONDO:0002938

Definition

A skin carcinoma displaying cytological characteristics intermediate to nodular basal cell carcinoma and squamous cell carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetatypical basal cell carcinoma

Professional guidelines

PubMed

Use of HSP105 in the Differential Diagnosis of Basaloid Skin Tumors: A Study of 73 Cases.
Deng LJ, Zhou KY, Wang QX, Luo SY, Fang S
Appl Immunohistochem Mol Morphol 2024 Oct 1;32(9):401-406. Epub 2024 Oct 8 doi: 10.1097/PAI.0000000000001224. PMID: 39514705

Recent clinical studies

Etiology

Metatypical Basal Cell Carcinoma: A 6-Year Retrospective Study.
Chaabane A, Bacha D, Ayachi K, Kilani H, Kanchel F, Douggaz A, Nechi S, Chelbi E
Skinmed 2019;17(1):24-28. Epub 2019 Mar 19 PMID: 30888944
The curious case of a forehead metatypical basal cell carcinoma.
Florescu IP, Turcu EG, Carantino AM, Cocoşilă LC, Enache V, Neagu TP, Jecan CR
Rom J Morphol Embryol 2018;59(1):345-352. PMID: 29940648
Basosquamous carcinoma and metatypical basal cell carcinoma: a review of treatment with Mohs micrographic surgery.
Allen KJ, Cappel MA, Killian JM, Brewer JD
Int J Dermatol 2014 Nov;53(11):1395-403. Epub 2014 Jun 25 doi: 10.1111/ijd.12587. PMID: 24961583
Basosquamous carcinoma.
Garcia C, Poletti E, Crowson AN
J Am Acad Dermatol 2009 Jan;60(1):137-43. doi: 10.1016/j.jaad.2008.09.036. PMID: 19103364
Metatypical basal cell carcinoma: a clinical review.
Tarallo M, Cigna E, Frati R, Delfino S, Innocenzi D, Fama U, Corbianco A, Scuderi N
J Exp Clin Cancer Res 2008 Nov 7;27(1):65. doi: 10.1186/1756-9966-27-65. PMID: 18992138Free PMC Article

Diagnosis

Basosquamous Carcinoma: Comprehensive Clinical and Histopathological Aspects, Novel Imaging Tools, and Therapeutic Approaches.
Murgia G, Denaro N, Boggio F, Nazzaro G, Benzecry V, Bortoluzzi P, Passoni E, Garrone O, Marzano A
Cells 2023 Nov 30;12(23) doi: 10.3390/cells12232737. PMID: 38067165Free PMC Article
Complex regional pain syndrome as a paraneoplastic disorder associated with metatypical basal cell carcinoma.
Gofiţă CE, Ciurea ME, Dinescu ŞC, Vreju AF, Stoica LE, Ciurea RN, Boldeanu MV, Rogoveanu OC, Trăistaru MR, Bumbea AM, Ciurea PL, Muşetescu AE
Rom J Morphol Embryol 2019;60(2):685-689. PMID: 31658345
Metatypical Basal Cell Carcinoma: A 6-Year Retrospective Study.
Chaabane A, Bacha D, Ayachi K, Kilani H, Kanchel F, Douggaz A, Nechi S, Chelbi E
Skinmed 2019;17(1):24-28. Epub 2019 Mar 19 PMID: 30888944
Basosquamous carcinoma.
Garcia C, Poletti E, Crowson AN
J Am Acad Dermatol 2009 Jan;60(1):137-43. doi: 10.1016/j.jaad.2008.09.036. PMID: 19103364
Metatypical basal cell carcinoma: a clinical review.
Tarallo M, Cigna E, Frati R, Delfino S, Innocenzi D, Fama U, Corbianco A, Scuderi N
J Exp Clin Cancer Res 2008 Nov 7;27(1):65. doi: 10.1186/1756-9966-27-65. PMID: 18992138Free PMC Article

Therapy

How to spot a basosquamous carcinoma: a study on demographics, clinical-dermatoscopic features and histopathological correlations.
Sgouros D, Apalla Z, Theofili M, Damaskou V, Kokkalis G, Kitsiou E, Lallas A, Kanelleas A, Stratigos A, Nikolaidou C, Bobos M, Panayiotides I, Rigopoulos D, Katoulis A
Eur J Dermatol 2021 Dec 1;31(6):779-784. doi: 10.1684/ejd.2021.4178. PMID: 34933836
Basosquamous Carcinoma: Controversy, Advances, and Future Directions.
Tan CZ, Rieger KE, Sarin KY
Dermatol Surg 2017 Jan;43(1):23-31. doi: 10.1097/DSS.0000000000000815. PMID: 27340741

Prognosis

Basosquamous Carcinoma: Comprehensive Clinical and Histopathological Aspects, Novel Imaging Tools, and Therapeutic Approaches.
Murgia G, Denaro N, Boggio F, Nazzaro G, Benzecry V, Bortoluzzi P, Passoni E, Garrone O, Marzano A
Cells 2023 Nov 30;12(23) doi: 10.3390/cells12232737. PMID: 38067165Free PMC Article
Metatypical basal cell carcinoma: from the primary tumour to a generalized metastatic process - description of diagnostics and combination therapy of an extremely rare skin cancer.
Madej-Czerwonka B, Korga-Plewko A
Ann Agric Environ Med 2022 Mar 21;29(1):152-156. Epub 2021 Apr 9 doi: 10.26444/aaem/134660. PMID: 35352920
The curious case of a forehead metatypical basal cell carcinoma.
Florescu IP, Turcu EG, Carantino AM, Cocoşilă LC, Enache V, Neagu TP, Jecan CR
Rom J Morphol Embryol 2018;59(1):345-352. PMID: 29940648
Basosquamous carcinoma and metatypical basal cell carcinoma: a review of treatment with Mohs micrographic surgery.
Allen KJ, Cappel MA, Killian JM, Brewer JD
Int J Dermatol 2014 Nov;53(11):1395-403. Epub 2014 Jun 25 doi: 10.1111/ijd.12587. PMID: 24961583
Basosquamous carcinoma.
Garcia C, Poletti E, Crowson AN
J Am Acad Dermatol 2009 Jan;60(1):137-43. doi: 10.1016/j.jaad.2008.09.036. PMID: 19103364

Clinical prediction guides

Mohs micrographic surgery in rare cutaneous tumors: a retrospective study at a Brazilian tertiary university hospital.
Buffo TH, Stelini RF, Serrano JYM, Pontes LT, Magalhães RF, de Moraes AM
An Bras Dermatol 2023 Jan-Feb;98(1):36-46. Epub 2022 Nov 8 doi: 10.1016/j.abd.2022.01.009. PMID: 36369200Free PMC Article
How to spot a basosquamous carcinoma: a study on demographics, clinical-dermatoscopic features and histopathological correlations.
Sgouros D, Apalla Z, Theofili M, Damaskou V, Kokkalis G, Kitsiou E, Lallas A, Kanelleas A, Stratigos A, Nikolaidou C, Bobos M, Panayiotides I, Rigopoulos D, Katoulis A
Eur J Dermatol 2021 Dec 1;31(6):779-784. doi: 10.1684/ejd.2021.4178. PMID: 34933836
The Use of a Polyetheretherketone (PEEK) Implant to Reconstruct the Midface Region.
Hussain RN, Clark M, Berry-Brincat A
Ophthalmic Plast Reconstr Surg 2016 Nov/Dec;32(6):e151-e153. doi: 10.1097/IOP.0000000000000345. PMID: 25393902
Basosquamous carcinoma.
Garcia C, Poletti E, Crowson AN
J Am Acad Dermatol 2009 Jan;60(1):137-43. doi: 10.1016/j.jaad.2008.09.036. PMID: 19103364

Recent systematic reviews

Basosquamous Carcinoma: Controversy, Advances, and Future Directions.
Tan CZ, Rieger KE, Sarin KY
Dermatol Surg 2017 Jan;43(1):23-31. doi: 10.1097/DSS.0000000000000815. PMID: 27340741

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