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Anal Necrotic Lesion

MedGen UID:
352158
•Concept ID:
C1697981
•
Disease or Syndrome

Definition

A necrotic process involving the area of the anus. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnal Necrotic Lesion

Professional guidelines

PubMed

Risk and management of intra-abdominal abscess in Crohn's disease treated with infliximab.
Yoneno K, Hisamatsu T, Matsuoka K, Okamoto S, Takayama T, Ichikawa R, Sujino T, Miyoshi J, Takabayashi K, Mikami Y, Mizuno S, Wada Y, Yajima T, Naganuma M, Inoue N, Iwao Y, Ogata H, Hasegawa H, Kitagawa Y, Hibi T, Kanai T
Digestion 2014;89(3):201-8. Epub 2014 May 1 doi: 10.1159/000360618. PMID: 24803137
Retrorectal developmental cysts in adults: clinical and radiologic-histopathologic review, differential diagnosis, and treatment.
Dahan H, Arrivé L, Wendum D, Docou le Pointe H, Djouhri H, Tubiana JM
Radiographics 2001 May-Jun;21(3):575-84. doi: 10.1148/radiographics.21.3.g01ma13575. PMID: 11353107
Management of perianal Crohn's disease.
Rutgeerts P
Can J Gastroenterol 2000 Sep;14 Suppl C:7C-12C. doi: 10.1155/2000/985045. PMID: 11023554

Recent clinical studies

Etiology

Natural History of Anal Ulcerations in Pediatric-Onset Crohn's Disease: Long-Term Follow-Up of a Population-Based Study.
Mortreux P, Leroyer A, Dupont C, Ley D, Bertrand V, Spyckerelle C, Guillon N, Wils P, Gower-Rousseau C, Savoye G, Fumery M, Turck D, Siproudhis L, Sarter H
Am J Gastroenterol 2023 Sep 1;118(9):1671-1678. Epub 2023 Apr 25 doi: 10.14309/ajg.0000000000002301. PMID: 37104674
Management of perianal fistulas in Crohn's disease: a 2021 update of the French National Society of Coloproctology consensus.
Bouchard D, Pigot F, de Parades V, Staumont G, Abramowitz L, Siproudhis L; Members of the SNFCP; Members of the GETAID
Tech Coloproctol 2022 Oct;26(10):805-811. Epub 2022 Aug 21 doi: 10.1007/s10151-022-02678-x. PMID: 35988122
An automated near-real time computational method for induction and treatment of scar-related ventricular tachycardias.
Campos FO, Neic A, Mendonca Costa C, Whitaker J, O'Neill M, Razavi R, Rinaldi CA, DanielScherr, Niederer SA, Plank G, Bishop MJ
Med Image Anal 2022 Aug;80:102483. Epub 2022 May 27 doi: 10.1016/j.media.2022.102483. PMID: 35667328Free PMC Article
Complications of colorectal resection for endometriosis.
Bouaziz J, Soriano D
Minerva Ginecol 2017 Oct;69(5):477-487. Epub 2017 Apr 4 doi: 10.23736/S0026-4784.17.04052-7. PMID: 28381079
Hidradenitis suppurativa.
Revuz J
J Eur Acad Dermatol Venereol 2009 Sep;23(9):985-98. doi: 10.1111/j.1468-3083.2009.03356.x. PMID: 19682181

Diagnosis

Combined Malonic and Methylmalonic Aciduria Diagnosed by Recurrent and Severe Infections Mimicking a Primary Immunodeficiency Disease: A Case Report.
Lee JK, Oh A
J Korean Med Sci 2023 Nov 20;38(45):e387. doi: 10.3346/jkms.2023.38.e387. PMID: 37987109Free PMC Article
Dose escalation of adalimumab as a strategy to overcome anti-drug antibodies: A case report of infantile-onset inflammatory bowel disease.
Ancona S, Signa S, Longo C, Cangemi G, Carfora R, Drago E, La Rosa A, Crocco M, Chiaro A, Gandullia P, Arrigo S
World J Gastroenterol 2023 Oct 14;29(38):5428-5434. doi: 10.3748/wjg.v29.i38.5428. PMID: 37900586Free PMC Article
Natural History of Anal Ulcerations in Pediatric-Onset Crohn's Disease: Long-Term Follow-Up of a Population-Based Study.
Mortreux P, Leroyer A, Dupont C, Ley D, Bertrand V, Spyckerelle C, Guillon N, Wils P, Gower-Rousseau C, Savoye G, Fumery M, Turck D, Siproudhis L, Sarter H
Am J Gastroenterol 2023 Sep 1;118(9):1671-1678. Epub 2023 Apr 25 doi: 10.14309/ajg.0000000000002301. PMID: 37104674
The Combination Strategy of Transarterial Chemoembolization and Radiofrequency Ablation or Microwave Ablation against Hepatocellular Carcinoma.
Xu Z, Xie H, Zhou L, Chen X, Zheng S
Anal Cell Pathol (Amst) 2019;2019:8619096. Epub 2019 Aug 26 doi: 10.1155/2019/8619096. PMID: 31534899Free PMC Article
Hidradenitis suppurativa.
Revuz J
J Eur Acad Dermatol Venereol 2009 Sep;23(9):985-98. doi: 10.1111/j.1468-3083.2009.03356.x. PMID: 19682181

Therapy

Dose escalation of adalimumab as a strategy to overcome anti-drug antibodies: A case report of infantile-onset inflammatory bowel disease.
Ancona S, Signa S, Longo C, Cangemi G, Carfora R, Drago E, La Rosa A, Crocco M, Chiaro A, Gandullia P, Arrigo S
World J Gastroenterol 2023 Oct 14;29(38):5428-5434. doi: 10.3748/wjg.v29.i38.5428. PMID: 37900586Free PMC Article
Management of perianal fistulas in Crohn's disease: a 2021 update of the French National Society of Coloproctology consensus.
Bouchard D, Pigot F, de Parades V, Staumont G, Abramowitz L, Siproudhis L; Members of the SNFCP; Members of the GETAID
Tech Coloproctol 2022 Oct;26(10):805-811. Epub 2022 Aug 21 doi: 10.1007/s10151-022-02678-x. PMID: 35988122
Anoperineal lesions in Crohn's disease: French recommendations for clinical practice.
Bouchard D, Abramowitz L, Bouguen G, Brochard C, Dabadie A, de Parades V, Eléouet-Kaplan M, Fathallah N, Faucheron JL, Maggiori L, Panis Y, Pigot F, Rouméguère P, Sénéjoux A, Siproudhis L, Staumont G, Suduca JM, Vinson-Bonnet B, Zeitoun JD
Tech Coloproctol 2017 Sep;21(9):683-691. Epub 2017 Sep 19 doi: 10.1007/s10151-017-1684-y. PMID: 28929282
Hidradenitis suppurativa.
Revuz J
J Eur Acad Dermatol Venereol 2009 Sep;23(9):985-98. doi: 10.1111/j.1468-3083.2009.03356.x. PMID: 19682181
Management of perianal Crohn's disease.
Rutgeerts P
Can J Gastroenterol 2000 Sep;14 Suppl C:7C-12C. doi: 10.1155/2000/985045. PMID: 11023554

Prognosis

Combined Malonic and Methylmalonic Aciduria Diagnosed by Recurrent and Severe Infections Mimicking a Primary Immunodeficiency Disease: A Case Report.
Lee JK, Oh A
J Korean Med Sci 2023 Nov 20;38(45):e387. doi: 10.3346/jkms.2023.38.e387. PMID: 37987109Free PMC Article
Dose escalation of adalimumab as a strategy to overcome anti-drug antibodies: A case report of infantile-onset inflammatory bowel disease.
Ancona S, Signa S, Longo C, Cangemi G, Carfora R, Drago E, La Rosa A, Crocco M, Chiaro A, Gandullia P, Arrigo S
World J Gastroenterol 2023 Oct 14;29(38):5428-5434. doi: 10.3748/wjg.v29.i38.5428. PMID: 37900586Free PMC Article
Natural History of Anal Ulcerations in Pediatric-Onset Crohn's Disease: Long-Term Follow-Up of a Population-Based Study.
Mortreux P, Leroyer A, Dupont C, Ley D, Bertrand V, Spyckerelle C, Guillon N, Wils P, Gower-Rousseau C, Savoye G, Fumery M, Turck D, Siproudhis L, Sarter H
Am J Gastroenterol 2023 Sep 1;118(9):1671-1678. Epub 2023 Apr 25 doi: 10.14309/ajg.0000000000002301. PMID: 37104674
The Conundrum of an Accumulating Acuminatum.
Cimmino A, Walters E, Gubler A, Ibrahim A
Am J Case Rep 2020 Feb 23;21:e920516. doi: 10.12659/AJCR.920516. PMID: 32088723Free PMC Article
Management of perianal Crohn's disease.
Rutgeerts P
Can J Gastroenterol 2000 Sep;14 Suppl C:7C-12C. doi: 10.1155/2000/985045. PMID: 11023554

Clinical prediction guides

Natural History of Anal Ulcerations in Pediatric-Onset Crohn's Disease: Long-Term Follow-Up of a Population-Based Study.
Mortreux P, Leroyer A, Dupont C, Ley D, Bertrand V, Spyckerelle C, Guillon N, Wils P, Gower-Rousseau C, Savoye G, Fumery M, Turck D, Siproudhis L, Sarter H
Am J Gastroenterol 2023 Sep 1;118(9):1671-1678. Epub 2023 Apr 25 doi: 10.14309/ajg.0000000000002301. PMID: 37104674
PerfU-Net: Baseline infarct estimation from CT perfusion source data for acute ischemic stroke.
de Vries L, Emmer BJ, Majoie CBLM, Marquering HA, Gavves E
Med Image Anal 2023 Apr;85:102749. Epub 2023 Jan 14 doi: 10.1016/j.media.2023.102749. PMID: 36731276
Human adipose and synovial mesenchymal stem cells improve osteoarthritis in rats by reducing chondrocyte reactive oxygen species and inhibiting inflammatory response.
Liu X, Liu Y, He H, Xiang W, He C
J Clin Lab Anal 2022 May;36(5):e24353. Epub 2022 Mar 21 doi: 10.1002/jcla.24353. PMID: 35312120Free PMC Article
Complications of colorectal resection for endometriosis.
Bouaziz J, Soriano D
Minerva Ginecol 2017 Oct;69(5):477-487. Epub 2017 Apr 4 doi: 10.23736/S0026-4784.17.04052-7. PMID: 28381079
Management of perianal Crohn's disease.
Rutgeerts P
Can J Gastroenterol 2000 Sep;14 Suppl C:7C-12C. doi: 10.1155/2000/985045. PMID: 11023554

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