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Familial chronic myelocytic leukemia-like syndrome

MedGen UID:
325075
Concept ID:
C1838670
Neoplastic Process
Synonym: CML-like syndrome, familial
 
Monarch Initiative: MONDO:0010809
OMIM®: 600080

Definition

A chronic myeloid leukemia characterized by chronic myelocytic leukemia in early infancy and absence of the BCR/ABL fusion gene (Philadelphia chromosome). [from MONDO]

Clinical features

From HPO
Chronic myelogenous leukemia, BCR-ABL1 positive
MedGen UID:
75993
Concept ID:
C0279543
Neoplastic Process
A myeloproliferative disorder characterized by increased proliferation of the granulocytic cell line without the loss of their capacity to differentiate.

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