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Colorectal cancer, susceptibility to, 1(CRCS1)

MedGen UID:
324734
Concept ID:
C1837315
Finding
Synonyms: COLORECTAL ADENOMA AND CANCER, SUSCEPTIBILITY TO; Colorectal cancer 1; COLORECTAL CANCER, SUSCEPTIBILITY TO, ON CHROMOSOME 9
 
Gene (location): GALNT12 (9q22.33)
 
Monarch Initiative: MONDO:0012132
OMIM®: 608812

Definition

Any colorectal cancer in which the cause of the disease is a mutation in the GALNT12 gene. [from MONDO]

Professional guidelines

PubMed

Valle L, Monahan KJ
Lancet Gastroenterol Hepatol 2024 Jan;9(1):68-82. Epub 2023 Nov 4 doi: 10.1016/S2468-1253(23)00240-6. PMID: 37931640
Zhu G, Pei L, Xia H, Tang Q, Bi F
Mol Cancer 2021 Nov 6;20(1):143. doi: 10.1186/s12943-021-01441-4. PMID: 34742312Free PMC Article
Cappell MS
Gastroenterol Clin North Am 2008 Mar;37(1):1-24, v. doi: 10.1016/j.gtc.2007.12.002. PMID: 18313537

Recent clinical studies

Etiology

Fujita M, Liu X, Iwasaki Y, Terao C, Mizukami K, Kawakami E, Takata S, Inai C, Aoi T, Mizukoshi M, Maejima K, Hirata M, Murakami Y, Kamatani Y, Kubo M, Akagi K, Matsuda K, Nakagawa H, Momozawa Y
Clin Gastroenterol Hepatol 2022 Sep;20(9):2132-2141.e9. Epub 2020 Dec 11 doi: 10.1016/j.cgh.2020.12.007. PMID: 33309985
Zhu G, Pei L, Xia H, Tang Q, Bi F
Mol Cancer 2021 Nov 6;20(1):143. doi: 10.1186/s12943-021-01441-4. PMID: 34742312Free PMC Article
Kasprzak A
Int J Mol Sci 2021 Jun 16;22(12) doi: 10.3390/ijms22126434. PMID: 34208601Free PMC Article
Mármol I, Sánchez-de-Diego C, Pradilla Dieste A, Cerrada E, Rodriguez Yoldi MJ
Int J Mol Sci 2017 Jan 19;18(1) doi: 10.3390/ijms18010197. PMID: 28106826Free PMC Article
Pearlman R, Frankel WL, Swanson B, Zhao W, Yilmaz A, Miller K, Bacher J, Bigley C, Nelsen L, Goodfellow PJ, Goldberg RM, Paskett E, Shields PG, Freudenheim JL, Stanich PP, Lattimer I, Arnold M, Liyanarachchi S, Kalady M, Heald B, Greenwood C, Paquette I, Prues M, Draper DJ, Lindeman C, Kuebler JP, Reynolds K, Brell JM, Shaper AA, Mahesh S, Buie N, Weeman K, Shine K, Haut M, Edwards J, Bastola S, Wickham K, Khanduja KS, Zacks R, Pritchard CC, Shirts BH, Jacobson A, Allen B, de la Chapelle A, Hampel H; Ohio Colorectal Cancer Prevention Initiative Study Group
JAMA Oncol 2017 Apr 1;3(4):464-471. doi: 10.1001/jamaoncol.2016.5194. PMID: 27978560Free PMC Article

Diagnosis

Spaander MCW, Zauber AG, Syngal S, Blaser MJ, Sung JJ, You YN, Kuipers EJ
Nat Rev Dis Primers 2023 Apr 27;9(1):21. doi: 10.1038/s41572-023-00432-7. PMID: 37105987Free PMC Article
Maratt JK, Stoffel E
Gastrointest Endosc Clin N Am 2022 Jan;32(1):45-58. doi: 10.1016/j.giec.2021.09.002. PMID: 34798986
Zhu G, Pei L, Xia H, Tang Q, Bi F
Mol Cancer 2021 Nov 6;20(1):143. doi: 10.1186/s12943-021-01441-4. PMID: 34742312Free PMC Article
Long F, Lin Z, Li L, Ma M, Lu Z, Jing L, Li X, Lin C
Mol Cancer 2021 Feb 3;20(1):26. doi: 10.1186/s12943-021-01318-6. PMID: 33536039Free PMC Article
Baidoun F, Elshiwy K, Elkeraie Y, Merjaneh Z, Khoudari G, Sarmini MT, Gad M, Al-Husseini M, Saad A
Curr Drug Targets 2021;22(9):998-1009. doi: 10.2174/1389450121999201117115717. PMID: 33208072

Therapy

Zhu G, Pei L, Xia H, Tang Q, Bi F
Mol Cancer 2021 Nov 6;20(1):143. doi: 10.1186/s12943-021-01441-4. PMID: 34742312Free PMC Article
Bull CJ, Bell JA, Murphy N, Sanderson E, Davey Smith G, Timpson NJ, Banbury BL, Albanes D, Berndt SI, Bézieau S, Bishop DT, Brenner H, Buchanan DD, Burnett-Hartman A, Casey G, Castellví-Bel S, Chan AT, Chang-Claude J, Cross AJ, de la Chapelle A, Figueiredo JC, Gallinger SJ, Gapstur SM, Giles GG, Gruber SB, Gsur A, Hampe J, Hampel H, Harrison TA, Hoffmeister M, Hsu L, Huang WY, Huyghe JR, Jenkins MA, Joshu CE, Keku TO, Kühn T, Kweon SS, Le Marchand L, Li CI, Li L, Lindblom A, Martín V, May AM, Milne RL, Moreno V, Newcomb PA, Offit K, Ogino S, Phipps AI, Platz EA, Potter JD, Qu C, Quirós JR, Rennert G, Riboli E, Sakoda LC, Schafmayer C, Schoen RE, Slattery ML, Tangen CM, Tsilidis KK, Ulrich CM, van Duijnhoven FJB, van Guelpen B, Visvanathan K, Vodicka P, Vodickova L, Wang H, White E, Wolk A, Woods MO, Wu AH, Campbell PT, Zheng W, Peters U, Vincent EE, Gunter MJ
BMC Med 2020 Dec 17;18(1):396. doi: 10.1186/s12916-020-01855-9. PMID: 33327948Free PMC Article
Papadimitriou N, Dimou N, Tsilidis KK, Banbury B, Martin RM, Lewis SJ, Kazmi N, Robinson TM, Albanes D, Aleksandrova K, Berndt SI, Timothy Bishop D, Brenner H, Buchanan DD, Bueno-de-Mesquita B, Campbell PT, Castellví-Bel S, Chan AT, Chang-Claude J, Ellingjord-Dale M, Figueiredo JC, Gallinger SJ, Giles GG, Giovannucci E, Gruber SB, Gsur A, Hampe J, Hampel H, Harlid S, Harrison TA, Hoffmeister M, Hopper JL, Hsu L, María Huerta J, Huyghe JR, Jenkins MA, Keku TO, Kühn T, La Vecchia C, Le Marchand L, Li CI, Li L, Lindblom A, Lindor NM, Lynch B, Markowitz SD, Masala G, May AM, Milne R, Monninkhof E, Moreno L, Moreno V, Newcomb PA, Offit K, Perduca V, Pharoah PDP, Platz EA, Potter JD, Rennert G, Riboli E, Sánchez MJ, Schmit SL, Schoen RE, Severi G, Sieri S, Slattery ML, Song M, Tangen CM, Thibodeau SN, Travis RC, Trichopoulou A, Ulrich CM, van Duijnhoven FJB, Van Guelpen B, Vodicka P, White E, Wolk A, Woods MO, Wu AH, Peters U, Gunter MJ, Murphy N
Nat Commun 2020 Jan 30;11(1):597. doi: 10.1038/s41467-020-14389-8. PMID: 32001714Free PMC Article
Le DT, Uram JN, Wang H, Bartlett BR, Kemberling H, Eyring AD, Skora AD, Luber BS, Azad NS, Laheru D, Biedrzycki B, Donehower RC, Zaheer A, Fisher GA, Crocenzi TS, Lee JJ, Duffy SM, Goldberg RM, de la Chapelle A, Koshiji M, Bhaijee F, Huebner T, Hruban RH, Wood LD, Cuka N, Pardoll DM, Papadopoulos N, Kinzler KW, Zhou S, Cornish TC, Taube JM, Anders RA, Eshleman JR, Vogelstein B, Diaz LA Jr
N Engl J Med 2015 Jun 25;372(26):2509-20. Epub 2015 May 30 doi: 10.1056/NEJMoa1500596. PMID: 26028255Free PMC Article
Imperiale TF, Ransohoff DF, Itzkowitz SH, Levin TR, Lavin P, Lidgard GP, Ahlquist DA, Berger BM
N Engl J Med 2014 Apr 3;370(14):1287-97. Epub 2014 Mar 19 doi: 10.1056/NEJMoa1311194. PMID: 24645800

Prognosis

Spaander MCW, Zauber AG, Syngal S, Blaser MJ, Sung JJ, You YN, Kuipers EJ
Nat Rev Dis Primers 2023 Apr 27;9(1):21. doi: 10.1038/s41572-023-00432-7. PMID: 37105987Free PMC Article
Maratt JK, Stoffel E
Gastrointest Endosc Clin N Am 2022 Jan;32(1):45-58. doi: 10.1016/j.giec.2021.09.002. PMID: 34798986
Zhu G, Pei L, Xia H, Tang Q, Bi F
Mol Cancer 2021 Nov 6;20(1):143. doi: 10.1186/s12943-021-01441-4. PMID: 34742312Free PMC Article
Baidoun F, Elshiwy K, Elkeraie Y, Merjaneh Z, Khoudari G, Sarmini MT, Gad M, Al-Husseini M, Saad A
Curr Drug Targets 2021;22(9):998-1009. doi: 10.2174/1389450121999201117115717. PMID: 33208072
Mármol I, Sánchez-de-Diego C, Pradilla Dieste A, Cerrada E, Rodriguez Yoldi MJ
Int J Mol Sci 2017 Jan 19;18(1) doi: 10.3390/ijms18010197. PMID: 28106826Free PMC Article

Clinical prediction guides

Spaander MCW, Zauber AG, Syngal S, Blaser MJ, Sung JJ, You YN, Kuipers EJ
Nat Rev Dis Primers 2023 Apr 27;9(1):21. doi: 10.1038/s41572-023-00432-7. PMID: 37105987Free PMC Article
Xin J, Du M, Gu D, Jiang K, Wang M, Jin M, Hu Y, Ben S, Chen S, Shao W, Li S, Chu H, Zhu L, Li C, Chen K, Ding K, Zhang Z, Shen H, Wang M
Genome Med 2023 Jan 24;15(1):4. doi: 10.1186/s13073-023-01156-9. PMID: 36694225Free PMC Article
Yamashita R, Long J, Longacre T, Peng L, Berry G, Martin B, Higgins J, Rubin DL, Shen J
Lancet Oncol 2021 Jan;22(1):132-141. doi: 10.1016/S1470-2045(20)30535-0. PMID: 33387492
Mármol I, Sánchez-de-Diego C, Pradilla Dieste A, Cerrada E, Rodriguez Yoldi MJ
Int J Mol Sci 2017 Jan 19;18(1) doi: 10.3390/ijms18010197. PMID: 28106826Free PMC Article
Yurgelun MB, Allen B, Kaldate RR, Bowles KR, Judkins T, Kaushik P, Roa BB, Wenstrup RJ, Hartman AR, Syngal S
Gastroenterology 2015 Sep;149(3):604-13.e20. Epub 2015 May 14 doi: 10.1053/j.gastro.2015.05.006. PMID: 25980754Free PMC Article

Recent systematic reviews

Mei J, Qian M, Hou Y, Liang M, Chen Y, Wang C, Zhang J
Lipids Health Dis 2024 Jan 30;23(1):32. doi: 10.1186/s12944-024-02025-z. PMID: 38291432Free PMC Article
Dixon P, Keeney E, Taylor JC, Wordsworth S, Martin RM
Genet Med 2022 Aug;24(8):1604-1617. Epub 2022 May 16 doi: 10.1016/j.gim.2022.04.020. PMID: 35575786Free PMC Article
Luo G, Zhang Y, Wang L, Huang Y, Yu Q, Guo P, Li K
Int J Surg 2016 Oct;34:88-95. Epub 2016 Aug 26 doi: 10.1016/j.ijsu.2016.08.518. PMID: 27568653
Fonseca-Nunes A, Jakszyn P, Agudo A
Cancer Epidemiol Biomarkers Prev 2014 Jan;23(1):12-31. Epub 2013 Nov 15 doi: 10.1158/1055-9965.EPI-13-0733. PMID: 24243555
Yu Y, Wang W, Zhai S, Dang S, Sun M
Mol Biol Rep 2012 Aug;39(8):8457-63. Epub 2012 Jun 20 doi: 10.1007/s11033-012-1699-4. PMID: 22714907

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