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Capsular Contracture

MedGen UID:
317484
•Concept ID:
C1707264
•
Finding

Definition

The tightening of scar tissue that forms around the implant. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCapsular Contracture

Professional guidelines

PubMed

Surgical Treatment of Capsular Contracture (CC): Literature Review and Outcomes Utilizing Implants in Revisionary Surgery.
Zingaretti N, Vittorini P, Savino V, Vittorini JC, De Francesco F, Riccio M, Parodi PC
Aesthetic Plast Surg 2021 Oct;45(5):2036-2047. Epub 2021 Feb 4 doi: 10.1007/s00266-021-02148-z. PMID: 33543344
Postirradiation Capsular Contracture in Implant-Based Breast Reconstruction: Management and Outcome.
Haran O, Bracha G, Tiosano A, Menes T, Madah E, Gur E, Barnea Y, Arad E
Plast Reconstr Surg 2021 Jan 1;147(1):11-19. doi: 10.1097/PRS.0000000000007453. PMID: 33002986
Posterior Glenohumeral Instability: Diagnosis and Management.
Sheean AJ, Arner JW, Bradley JP
Arthroscopy 2020 Oct;36(10):2580-2582. Epub 2020 May 20 doi: 10.1016/j.arthro.2020.05.018. PMID: 32442706

Recent clinical studies

Etiology

The Keller Funnel, Capsular Contracture, and Conflict of Interest: A Review.
Swanson E
Ann Plast Surg 2023 Aug 1;91(2):301-306. Epub 2023 Jun 1 doi: 10.1097/SAP.0000000000003549. PMID: 37347153Free PMC Article
Incision and Capsular Contracture Risk: Is There a Relationship in Breast Augmentation and Augmentation/Mastopexy?
Swanson E
Ann Plast Surg 2023 Apr 1;90(4):389-391. Epub 2023 Feb 15 doi: 10.1097/SAP.0000000000003437. PMID: 37093773Free PMC Article
Hot Topics in Breast Surgery.
Austin RE, Lista F, Ahmad J
Clin Plast Surg 2021 Jan;48(1):131-139. Epub 2020 Nov 3 doi: 10.1016/j.cps.2020.09.004. PMID: 33220900
Silicone and autoimmunity.
Hajdu SD, Agmon-Levin N, Shoenfeld Y
Eur J Clin Invest 2011 Feb;41(2):203-11. Epub 2010 Sep 29 doi: 10.1111/j.1365-2362.2010.02389.x. PMID: 20880074
Breast augmentation.
Pelosi MA 3rd, Pelosi MA 2nd
Obstet Gynecol Clin North Am 2010 Dec;37(4):533-46, viii. doi: 10.1016/j.ogc.2010.09.003. PMID: 21093748

Diagnosis

Management of Symptomatic Patients with Textured Implants.
Asaad M, Offodile AC, Santanelli Di Pompeo F, Bevers TB, Stelly S, Carew LA, Barnea Y, Miranda RN, Butler CE, Clemens MW
Plast Reconstr Surg 2021 May 1;147(5S):58S-68S. doi: 10.1097/PRS.0000000000008047. PMID: 33890882
Round Form-Stable Breast Implants: Diagnosis and Management of Complications.
Nahabedian MY
Plast Reconstr Surg 2019 Jul;144(1S Utilizing a Spectrum of Cohesive Implants in Aesthetic and Reconstructive Breast Surgery):73S-81S. doi: 10.1097/PRS.0000000000005953. PMID: 31246764
Frozen shoulder.
Robinson CM, Seah KT, Chee YH, Hindle P, Murray IR
J Bone Joint Surg Br 2012 Jan;94(1):1-9. doi: 10.1302/0301-620X.94B1.27093. PMID: 22219239
Wrist arthrofibrosis.
Lee SK, Gargano F, Hausman MR
Hand Clin 2006 Nov;22(4):529-38; abstract vii. doi: 10.1016/j.hcl.2006.09.002. PMID: 17097472
Infection in breast implants.
Pittet B, Montandon D, Pittet D
Lancet Infect Dis 2005 Feb;5(2):94-106. doi: 10.1016/S1473-3099(05)01281-8. PMID: 15680779

Therapy

The Keller Funnel, Capsular Contracture, and Conflict of Interest: A Review.
Swanson E
Ann Plast Surg 2023 Aug 1;91(2):301-306. Epub 2023 Jun 1 doi: 10.1097/SAP.0000000000003549. PMID: 37347153Free PMC Article
Incision and Capsular Contracture Risk: Is There a Relationship in Breast Augmentation and Augmentation/Mastopexy?
Swanson E
Ann Plast Surg 2023 Apr 1;90(4):389-391. Epub 2023 Feb 15 doi: 10.1097/SAP.0000000000003437. PMID: 37093773Free PMC Article
Hot Topics in Breast Surgery.
Austin RE, Lista F, Ahmad J
Clin Plast Surg 2021 Jan;48(1):131-139. Epub 2020 Nov 3 doi: 10.1016/j.cps.2020.09.004. PMID: 33220900
Breast augmentation.
Hidalgo DA, Spector JA
Plast Reconstr Surg 2014 Apr;133(4):567e-583e. doi: 10.1097/PRS.0000000000000033. PMID: 24675209
Silicone and autoimmunity.
Hajdu SD, Agmon-Levin N, Shoenfeld Y
Eur J Clin Invest 2011 Feb;41(2):203-11. Epub 2010 Sep 29 doi: 10.1111/j.1365-2362.2010.02389.x. PMID: 20880074

Prognosis

Postirradiation Capsular Contracture in Implant-Based Breast Reconstruction: Management and Outcome.
Haran O, Bracha G, Tiosano A, Menes T, Madah E, Gur E, Barnea Y, Arad E
Plast Reconstr Surg 2021 Jan 1;147(1):11-19. doi: 10.1097/PRS.0000000000007453. PMID: 33002986
Capsular contracture in patients with prior breast augmentation undergoing breast conserving therapy and irradiation.
Serritzlev MS, Lorentzen AK, Matthiessen LW, Hölmich LR
J Plast Surg Hand Surg 2020 Aug;54(4):225-232. Epub 2020 May 7 doi: 10.1080/2000656X.2020.1755299. PMID: 32375532
Cosmetic reconstruction in breast cancer patients: Opportunities for nanocomposite materials.
Prasad K, Zhou R, Zhou R, Schuessler D, Ostrikov KK, Bazaka K
Acta Biomater 2019 Mar 1;86:41-65. Epub 2018 Dec 18 doi: 10.1016/j.actbio.2018.12.024. PMID: 30576863
Frozen shoulder.
Robinson CM, Seah KT, Chee YH, Hindle P, Murray IR
J Bone Joint Surg Br 2012 Jan;94(1):1-9. doi: 10.1302/0301-620X.94B1.27093. PMID: 22219239
Silicone and autoimmunity.
Hajdu SD, Agmon-Levin N, Shoenfeld Y
Eur J Clin Invest 2011 Feb;41(2):203-11. Epub 2010 Sep 29 doi: 10.1111/j.1365-2362.2010.02389.x. PMID: 20880074

Clinical prediction guides

Prepectoral Versus Subpectoral Implant-Based Breast Reconstruction: A Systemic Review and Meta-analysis.
Ostapenko E, Nixdorf L, Devyatko Y, Exner R, Wimmer K, Fitzal F
Ann Surg Oncol 2023 Jan;30(1):126-136. Epub 2022 Oct 16 doi: 10.1245/s10434-022-12567-0. PMID: 36245049Free PMC Article
Management of Symptomatic Patients with Textured Implants.
Asaad M, Offodile AC, Santanelli Di Pompeo F, Bevers TB, Stelly S, Carew LA, Barnea Y, Miranda RN, Butler CE, Clemens MW
Plast Reconstr Surg 2021 May 1;147(5S):58S-68S. doi: 10.1097/PRS.0000000000008047. PMID: 33890882
Capsular contracture in patients with prior breast augmentation undergoing breast conserving therapy and irradiation.
Serritzlev MS, Lorentzen AK, Matthiessen LW, Hölmich LR
J Plast Surg Hand Surg 2020 Aug;54(4):225-232. Epub 2020 May 7 doi: 10.1080/2000656X.2020.1755299. PMID: 32375532
Cosmetic reconstruction in breast cancer patients: Opportunities for nanocomposite materials.
Prasad K, Zhou R, Zhou R, Schuessler D, Ostrikov KK, Bazaka K
Acta Biomater 2019 Mar 1;86:41-65. Epub 2018 Dec 18 doi: 10.1016/j.actbio.2018.12.024. PMID: 30576863
Silicone and autoimmunity.
Hajdu SD, Agmon-Levin N, Shoenfeld Y
Eur J Clin Invest 2011 Feb;41(2):203-11. Epub 2010 Sep 29 doi: 10.1111/j.1365-2362.2010.02389.x. PMID: 20880074

Recent systematic reviews

Prepectoral Versus Subpectoral Implant-Based Breast Reconstruction: A Systemic Review and Meta-analysis.
Ostapenko E, Nixdorf L, Devyatko Y, Exner R, Wimmer K, Fitzal F
Ann Surg Oncol 2023 Jan;30(1):126-136. Epub 2022 Oct 16 doi: 10.1245/s10434-022-12567-0. PMID: 36245049Free PMC Article
Reduced capsular contracture with smooth and textured breast implants following submuscular mammoplasty: systematic literature review.
Zhu L, Zhu J, Qian Y, Jiang H
Future Oncol 2021 Dec;17(36):5177-5187. Epub 2021 Nov 3 doi: 10.2217/fon-2021-0510. PMID: 34730405
Histological Analyses of Capsular Contracture and Associated Risk Factors: A Systematic Review.
Larsen A, Rasmussen LE, Rasmussen LF, Weltz TK, Hemmingsen MN, Poulsen SS, Jacobsen JCB, Vester-Glowinski P, Herly M
Aesthetic Plast Surg 2021 Dec;45(6):2714-2728. Epub 2021 Jul 26 doi: 10.1007/s00266-021-02473-3. PMID: 34312696
Examining the Role of Antimicrobial Irrigation and Capsular Contracture: A Systematic Review and Meta-analysis.
Drinane JJ, Chowdhry T, Pham TH, Ritter E
Ann Plast Surg 2017 Jul;79(1):107-114. doi: 10.1097/SAP.0000000000001134. PMID: 28542075
Revisiting the Management of Capsular Contracture in Breast Augmentation: A Systematic Review.
Wan D, Rohrich RJ
Plast Reconstr Surg 2016 Mar;137(3):826-841. doi: 10.1097/01.prs.0000480095.23356.ae. PMID: 26910663

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