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Colonic pseudo-obstruction

MedGen UID:
3167
Concept ID:
C0009377
Disease or Syndrome
Synonyms: Colonic Pseudo Obstruction; Colonic Pseudo-Obstruction; Colonic Pseudoobstruction; Pseudo-Obstruction, Colonic; Pseudoobstruction, Colonic
SNOMED CT: Pseudo-obstruction of colon (721680006); Primary chronic pseudo-obstruction of colon (35065006)
 
Monarch Initiative: MONDO:0002801

Definition

Functional obstruction of the colon leading to megacolon in the absence of obvious colonic diseases or mechanical obstruction. When this condition is acquired, acute, and coexisting with another medical condition (trauma, surgery, serious injuries or illness, or medication), it is called Ogilvie's syndrome. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColonic pseudo-obstruction

Professional guidelines

PubMed

Sen A, Chokshi R
Curr Gastroenterol Rep 2023 Sep;25(9):191-197. Epub 2023 Jul 24 doi: 10.1007/s11894-023-00881-w. PMID: 37486594
Alavi K, Poylin V, Davids JS, Patel SV, Felder S, Valente MA, Paquette IM, Feingold DL; Prepared on behalf of the Clinical Practice Guidelines Committee of the American Society of Colon and Rectal Surgeons
Dis Colon Rectum 2021 Sep 1;64(9):1046-1057. doi: 10.1097/DCR.0000000000002159. PMID: 34016826
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845

Recent clinical studies

Etiology

Reignier J, Boisramé-Helms J, Brisard L, Lascarrou JB, Ait Hssain A, Anguel N, Argaud L, Asehnoune K, Asfar P, Bellec F, Botoc V, Bretagnol A, Bui HN, Canet E, Da Silva D, Darmon M, Das V, Devaquet J, Djibre M, Ganster F, Garrouste-Orgeas M, Gaudry S, Gontier O, Guérin C, Guidet B, Guitton C, Herbrecht JE, Lacherade JC, Letocart P, Martino F, Maxime V, Mercier E, Mira JP, Nseir S, Piton G, Quenot JP, Richecoeur J, Rigaud JP, Robert R, Rolin N, Schwebel C, Sirodot M, Tinturier F, Thévenin D, Giraudeau B, Le Gouge A; NUTRIREA-2 Trial Investigators; Clinical Research in Intensive Care and Sepsis (CRICS) group
Lancet 2018 Jan 13;391(10116):133-143. Epub 2017 Nov 8 doi: 10.1016/S0140-6736(17)32146-3. PMID: 29128300
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845
Pereira P, Djeudji F, Leduc P, Fanget F, Barth X
J Visc Surg 2015 Apr;152(2):99-105. Epub 2015 Mar 11 doi: 10.1016/j.jviscsurg.2015.02.004. PMID: 25770746
Durai R
Singapore Med J 2009 Mar;50(3):237-44. PMID: 19352564
Saunders MD
Best Pract Res Clin Gastroenterol 2007;21(4):671-87. doi: 10.1016/j.bpg.2007.03.001. PMID: 17643908

Diagnosis

Sen A, Chokshi R
Curr Gastroenterol Rep 2023 Sep;25(9):191-197. Epub 2023 Jul 24 doi: 10.1007/s11894-023-00881-w. PMID: 37486594
Alavi K, Poylin V, Davids JS, Patel SV, Felder S, Valente MA, Paquette IM, Feingold DL; Prepared on behalf of the Clinical Practice Guidelines Committee of the American Society of Colon and Rectal Surgeons
Dis Colon Rectum 2021 Sep 1;64(9):1046-1057. doi: 10.1097/DCR.0000000000002159. PMID: 34016826
Naveed M, Jamil LH, Fujii-Lau LL, Al-Haddad M, Buxbaum JL, Fishman DS, Jue TL, Law JK, Lee JK, Qumseya BJ, Sawhney MS, Thosani N, Storm AC, Calderwood AH, Khashab MA, Wani SB
Gastrointest Endosc 2020 Feb;91(2):228-235. Epub 2019 Nov 30 doi: 10.1016/j.gie.2019.09.007. PMID: 31791596
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845
Pereira P, Djeudji F, Leduc P, Fanget F, Barth X
J Visc Surg 2015 Apr;152(2):99-105. Epub 2015 Mar 11 doi: 10.1016/j.jviscsurg.2015.02.004. PMID: 25770746

Therapy

Sen A, Chokshi R
Curr Gastroenterol Rep 2023 Sep;25(9):191-197. Epub 2023 Jul 24 doi: 10.1007/s11894-023-00881-w. PMID: 37486594
Alavi K, Poylin V, Davids JS, Patel SV, Felder S, Valente MA, Paquette IM, Feingold DL; Prepared on behalf of the Clinical Practice Guidelines Committee of the American Society of Colon and Rectal Surgeons
Dis Colon Rectum 2021 Sep 1;64(9):1046-1057. doi: 10.1097/DCR.0000000000002159. PMID: 34016826
Naveed M, Jamil LH, Fujii-Lau LL, Al-Haddad M, Buxbaum JL, Fishman DS, Jue TL, Law JK, Lee JK, Qumseya BJ, Sawhney MS, Thosani N, Storm AC, Calderwood AH, Khashab MA, Wani SB
Gastrointest Endosc 2020 Feb;91(2):228-235. Epub 2019 Nov 30 doi: 10.1016/j.gie.2019.09.007. PMID: 31791596
Reignier J, Boisramé-Helms J, Brisard L, Lascarrou JB, Ait Hssain A, Anguel N, Argaud L, Asehnoune K, Asfar P, Bellec F, Botoc V, Bretagnol A, Bui HN, Canet E, Da Silva D, Darmon M, Das V, Devaquet J, Djibre M, Ganster F, Garrouste-Orgeas M, Gaudry S, Gontier O, Guérin C, Guidet B, Guitton C, Herbrecht JE, Lacherade JC, Letocart P, Martino F, Maxime V, Mercier E, Mira JP, Nseir S, Piton G, Quenot JP, Richecoeur J, Rigaud JP, Robert R, Rolin N, Schwebel C, Sirodot M, Tinturier F, Thévenin D, Giraudeau B, Le Gouge A; NUTRIREA-2 Trial Investigators; Clinical Research in Intensive Care and Sepsis (CRICS) group
Lancet 2018 Jan 13;391(10116):133-143. Epub 2017 Nov 8 doi: 10.1016/S0140-6736(17)32146-3. PMID: 29128300
Pereira P, Djeudji F, Leduc P, Fanget F, Barth X
J Visc Surg 2015 Apr;152(2):99-105. Epub 2015 Mar 11 doi: 10.1016/j.jviscsurg.2015.02.004. PMID: 25770746

Prognosis

Johnny CS, Schlegel RN, Balachandran M, Casey L, Mathew J, Carne P, Varma D, Ban EJ, Fitzgerald MC
J Trauma Acute Care Surg 2024 Oct 1;97(4):614-622. Epub 2024 May 21 doi: 10.1097/TA.0000000000004392. PMID: 38769618
Mankaney GN, Sarvepalli S, Arora Z, Kamal A, Lopez R, Vargo JJ, Burke CA
Dis Colon Rectum 2020 Jan;63(1):60-67. doi: 10.1097/DCR.0000000000001492. PMID: 31567918
Reignier J, Boisramé-Helms J, Brisard L, Lascarrou JB, Ait Hssain A, Anguel N, Argaud L, Asehnoune K, Asfar P, Bellec F, Botoc V, Bretagnol A, Bui HN, Canet E, Da Silva D, Darmon M, Das V, Devaquet J, Djibre M, Ganster F, Garrouste-Orgeas M, Gaudry S, Gontier O, Guérin C, Guidet B, Guitton C, Herbrecht JE, Lacherade JC, Letocart P, Martino F, Maxime V, Mercier E, Mira JP, Nseir S, Piton G, Quenot JP, Richecoeur J, Rigaud JP, Robert R, Rolin N, Schwebel C, Sirodot M, Tinturier F, Thévenin D, Giraudeau B, Le Gouge A; NUTRIREA-2 Trial Investigators; Clinical Research in Intensive Care and Sepsis (CRICS) group
Lancet 2018 Jan 13;391(10116):133-143. Epub 2017 Nov 8 doi: 10.1016/S0140-6736(17)32146-3. PMID: 29128300
Wells CI, O'Grady G, Bissett IP
World J Gastroenterol 2017 Aug 14;23(30):5634-5644. doi: 10.3748/wjg.v23.i30.5634. PMID: 28852322Free PMC Article
Durai R
Singapore Med J 2009 Mar;50(3):237-44. PMID: 19352564

Clinical prediction guides

Johnny CS, Schlegel RN, Balachandran M, Casey L, Mathew J, Carne P, Varma D, Ban EJ, Fitzgerald MC
J Trauma Acute Care Surg 2024 Oct 1;97(4):614-622. Epub 2024 May 21 doi: 10.1097/TA.0000000000004392. PMID: 38769618
Christensen K, Ostersen LH, Glavind K, Krarup AL, Kjærgaard N
Eur J Obstet Gynecol Reprod Biol 2020 Sep;252:418-423. Epub 2020 Jul 3 doi: 10.1016/j.ejogrb.2020.06.011. PMID: 32721839
Mankaney GN, Sarvepalli S, Arora Z, Kamal A, Lopez R, Vargo JJ, Burke CA
Dis Colon Rectum 2020 Jan;63(1):60-67. doi: 10.1097/DCR.0000000000001492. PMID: 31567918
Haj M, Haj M, Rockey DC
Medicine (Baltimore) 2018 Jul;97(27):e11187. doi: 10.1097/MD.0000000000011187. PMID: 29979381Free PMC Article
Elsner JL, Smith JM, Ensor CR
Ann Pharmacother 2012 Mar;46(3):430-5. Epub 2012 Feb 28 doi: 10.1345/aph.1Q515. PMID: 22388328

Recent systematic reviews

Wells CI, O'Grady G, Bissett IP
World J Gastroenterol 2017 Aug 14;23(30):5634-5644. doi: 10.3748/wjg.v23.i30.5634. PMID: 28852322Free PMC Article
Jayaram P, Mohan M, Lindow S, Konje J
Eur J Obstet Gynecol Reprod Biol 2017 Jul;214:145-149. Epub 2017 May 2 doi: 10.1016/j.ejogrb.2017.04.028. PMID: 28531835
Rami Reddy SR, Cappell MS
Curr Gastroenterol Rep 2017 Jun;19(6):28. doi: 10.1007/s11894-017-0566-9. PMID: 28439845
De Giorgio R, Knowles CH
Br J Surg 2009 Mar;96(3):229-39. doi: 10.1002/bjs.6480. PMID: 19224517
Saunders MD, Kimmey MB
Aliment Pharmacol Ther 2005 Nov 15;22(10):917-25. doi: 10.1111/j.1365-2036.2005.02668.x. PMID: 16268965

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