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Rectosigmoid Mucinous Adenocarcinoma

MedGen UID:
311207
•Concept ID:
C1709867
•
Neoplastic Process

Definition

An invasive adenocarcinoma of the rectosigmoid area characterized by the presence of pools of extracellular mucin. Malignant glandular epithelial cells are present in the mucin collections. Mucin constitutes more than 50% of the lesion. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRectosigmoid Mucinous Adenocarcinoma

Professional guidelines

PubMed

Pseudomyxoma peritonei: natural history and treatment.
Mittal R, Chandramohan A, Moran B
Int J Hyperthermia 2017 Aug;33(5):511-519. doi: 10.1080/02656736.2017.1310938. PMID: 28540829
En-bloc pelvic resection with concomitant rectosigmoid colectomy and immediate anastomosis as part of primary cytoreductive surgery for patients with advanced ovarian cancer.
Yildirim Y, Ertas IE, Nayki U, Ulug P, Nayki C, Yilmaz I, Gultekin E, Dogan A, Aykas A, Ulug S, Ozdemir A, Solmaz U
Eur J Gynaecol Oncol 2014;35(4):400-7. PMID: 25118481

Recent clinical studies

Etiology

Clinical, endoscopic and histological profile of colorectal cancers seen on colonoscopy in Kano, North-Western Nigeria.
Musa Y, Mohammed MF, Muhammad NO, Yusuf I, Abdulrahim AO, Samaila AA, Borodo MM
Niger Postgrad Med J 2021 Jan-Mar;28(1):22-26. doi: 10.4103/npmj.npmj_288_20. PMID: 33642320
Different clinical characteristics in sporadic young-age onset colorectal cancer.
Lee J, Kim IH, Kim JS, Kim SW, Kim JG, Oh ST, Kang WK, Lee MA
Medicine (Baltimore) 2016 Sep;95(37):e4840. doi: 10.1097/MD.0000000000004840. PMID: 27631240Free PMC Article
A novel risk-adjusted nomogram for rectal cancer surgery outcomes.
Russell MC, You YN, Hu CY, Cormier JN, Feig BW, Skibber JM, Rodriguez-Bigas MA, Nelson H, Chang GJ
JAMA Surg 2013 Aug;148(8):769-77. doi: 10.1001/jamasurg.2013.2136. PMID: 23803722Free PMC Article
Colorectal carcinoma in Lagos and Sagamu, Southwest Nigeria: a histopathological review.
Abdulkareem FB, Abudu EK, Awolola NA, Elesha SO, Rotimi O, Akinde OR, Atoyebi AO, Adesanya AA, Daramola AO, Banjo AA, Anunobi CC
World J Gastroenterol 2008 Nov 14;14(42):6531-5. doi: 10.3748/wjg.14.6531. PMID: 19030207Free PMC Article
Colorectal carcinoma in children.
Karnak I, Ciftci AO, Senocak ME, Büyükpamukçu N
J Pediatr Surg 1999 Oct;34(10):1499-504. doi: 10.1016/s0022-3468(99)90112-4. PMID: 10549756

Diagnosis

Clinical, endoscopic and histological profile of colorectal cancers seen on colonoscopy in Kano, North-Western Nigeria.
Musa Y, Mohammed MF, Muhammad NO, Yusuf I, Abdulrahim AO, Samaila AA, Borodo MM
Niger Postgrad Med J 2021 Jan-Mar;28(1):22-26. doi: 10.4103/npmj.npmj_288_20. PMID: 33642320
Pseudomyxoma peritonei: natural history and treatment.
Mittal R, Chandramohan A, Moran B
Int J Hyperthermia 2017 Aug;33(5):511-519. doi: 10.1080/02656736.2017.1310938. PMID: 28540829
A novel risk-adjusted nomogram for rectal cancer surgery outcomes.
Russell MC, You YN, Hu CY, Cormier JN, Feig BW, Skibber JM, Rodriguez-Bigas MA, Nelson H, Chang GJ
JAMA Surg 2013 Aug;148(8):769-77. doi: 10.1001/jamasurg.2013.2136. PMID: 23803722Free PMC Article
Colorectal carcinoma in Lagos and Sagamu, Southwest Nigeria: a histopathological review.
Abdulkareem FB, Abudu EK, Awolola NA, Elesha SO, Rotimi O, Akinde OR, Atoyebi AO, Adesanya AA, Daramola AO, Banjo AA, Anunobi CC
World J Gastroenterol 2008 Nov 14;14(42):6531-5. doi: 10.3748/wjg.14.6531. PMID: 19030207Free PMC Article
Colorectal carcinoma in children.
Karnak I, Ciftci AO, Senocak ME, Büyükpamukçu N
J Pediatr Surg 1999 Oct;34(10):1499-504. doi: 10.1016/s0022-3468(99)90112-4. PMID: 10549756

Therapy

Colorectal carcinoma in children.
Karnak I, Ciftci AO, Senocak ME, Büyükpamukçu N
J Pediatr Surg 1999 Oct;34(10):1499-504. doi: 10.1016/s0022-3468(99)90112-4. PMID: 10549756
Colorectal cancer after irradiation for cervical cancer--case reports.
Kimura T, Iwagaki H, Hizuta A, Nonaka Y, Tanaka N, Orita K
Anticancer Res 1995 Mar-Apr;15(2):557-8. PMID: 7763037
Nd-YAG laser therapy for palliation of obstructed colorectal carcinomas.
Rau BK, Harikrishnan KM, Krishna S
Indian J Cancer 1994 Dec;31(4):240-3. PMID: 7875725

Prognosis

Oncological outcome of carcinomas in the rectosigmoid junction compared to the upper rectum or sigmoid colon - A retrospective cohort study.
Falch C, Mueller S, Braun M, Gani C, Fend F, Koenigsrainer A, Kirschniak A
Eur J Surg Oncol 2019 Nov;45(11):2037-2044. Epub 2019 Jun 18 doi: 10.1016/j.ejso.2019.06.024. PMID: 31239157
Clinicopathological patterns and challenges of management of colorectal cancer in a resource-limited setting: a Tanzanian experience.
Chalya PL, McHembe MD, Mabula JB, Rambau PF, Jaka H, Koy M, Mkongo E, Masalu N
World J Surg Oncol 2013 Apr 18;11:88. doi: 10.1186/1477-7819-11-88. PMID: 23597032Free PMC Article
Different patterns of lymphatic spread of sigmoid, rectosigmoid, and rectal cancers.
Park IJ, Choi GS, Lim KH, Kang BM, Jun SH
Ann Surg Oncol 2008 Dec;15(12):3478-83. Epub 2008 Oct 1 doi: 10.1245/s10434-008-0158-x. PMID: 18830668
Colorectal carcinoma in children.
Karnak I, Ciftci AO, Senocak ME, Büyükpamukçu N
J Pediatr Surg 1999 Oct;34(10):1499-504. doi: 10.1016/s0022-3468(99)90112-4. PMID: 10549756
Clinicopathological study of colorectal mucinous carcinoma in Taiwan: a multivariate analysis.
Wu CS, Tung SY, Chen PC, Kuo YC
J Gastroenterol Hepatol 1996 Jan;11(1):77-81. doi: 10.1111/j.1440-1746.1996.tb00014.x. PMID: 8672747

Clinical prediction guides

Different clinical characteristics in sporadic young-age onset colorectal cancer.
Lee J, Kim IH, Kim JS, Kim SW, Kim JG, Oh ST, Kang WK, Lee MA
Medicine (Baltimore) 2016 Sep;95(37):e4840. doi: 10.1097/MD.0000000000004840. PMID: 27631240Free PMC Article
Results of optimal debulking surgery with bowel resection in patients with advanced ovarian cancer.
Derlatka P, Sienko J, Grabowska-Derlatka L, Palczewski P, Danska-Bidzinska A, Bidzinski M, Czajkowski K
World J Surg Oncol 2016 Feb 29;14:58. doi: 10.1186/s12957-016-0800-1. PMID: 26923029Free PMC Article
A novel risk-adjusted nomogram for rectal cancer surgery outcomes.
Russell MC, You YN, Hu CY, Cormier JN, Feig BW, Skibber JM, Rodriguez-Bigas MA, Nelson H, Chang GJ
JAMA Surg 2013 Aug;148(8):769-77. doi: 10.1001/jamasurg.2013.2136. PMID: 23803722Free PMC Article
Colorectal carcinoma in children.
Karnak I, Ciftci AO, Senocak ME, Büyükpamukçu N
J Pediatr Surg 1999 Oct;34(10):1499-504. doi: 10.1016/s0022-3468(99)90112-4. PMID: 10549756
Clinicopathological study of colorectal mucinous carcinoma in Taiwan: a multivariate analysis.
Wu CS, Tung SY, Chen PC, Kuo YC
J Gastroenterol Hepatol 1996 Jan;11(1):77-81. doi: 10.1111/j.1440-1746.1996.tb00014.x. PMID: 8672747

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