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Pituitary Neuroendocrine Tumor/Microadenoma

MedGen UID:
311126
•Concept ID:
C1709552
•
Neoplastic Process
Synonyms: PitNET/Microadenoma; Pituitary Gland Microadenoma

Definition

A pituitary neuroendocrine tumor with a diameter equal or less than 10 mm. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPituitary Neuroendocrine Tumor/Microadenoma

Professional guidelines

PubMed

Diagnosis and Management of Pituitary Adenomas: A Review.
Tritos NA, Miller KK
JAMA 2023 Apr 25;329(16):1386-1398. doi: 10.1001/jama.2023.5444. PMID: 37097352
Update on the clinical management of multiple endocrine neoplasia type 1.
Pieterman CRC, Valk GD
Clin Endocrinol (Oxf) 2022 Oct;97(4):409-423. Epub 2022 Apr 1 doi: 10.1111/cen.14727. PMID: 35319130Free PMC Article
Diagnosis and Treatment of Pituitary Adenomas: A Review.
Molitch ME
JAMA 2017 Feb 7;317(5):516-524. doi: 10.1001/jama.2016.19699. PMID: 28170483

Recent clinical studies

Therapy

Diagnosis and Management of Pituitary Adenomas: A Review.
Tritos NA, Miller KK
JAMA 2023 Apr 25;329(16):1386-1398. doi: 10.1001/jama.2023.5444. PMID: 37097352
Diagnosis and Treatment of Pituitary Adenomas: A Review.
Molitch ME
JAMA 2017 Feb 7;317(5):516-524. doi: 10.1001/jama.2016.19699. PMID: 28170483
The safety of treatments for prolactinomas.
Auriemma RS, Grasso LF, Pivonello R, Colao A
Expert Opin Drug Saf 2016;15(4):503-12. Epub 2016 Mar 7 doi: 10.1517/14740338.2016.1151493. PMID: 26855238
Prolactinoma in pregnancy.
Molitch ME
Best Pract Res Clin Endocrinol Metab 2011 Dec;25(6):885-96. doi: 10.1016/j.beem.2011.05.011. PMID: 22115164
Acromegaly.
Ben-Shlomo A, Melmed S
Endocrinol Metab Clin North Am 2008 Mar;37(1):101-22, viii. doi: 10.1016/j.ecl.2007.10.002. PMID: 18226732Free PMC Article

Prognosis

Aggressive pituitary tumours and carcinomas, characteristics and management of 171 patients.
Burman P, Trouillas J, Losa M, McCormack A, Petersenn S, Popovic V, Theodoropoulou M, Raverot G, Dekkers OM; ESE survey collaborators †
Eur J Endocrinol 2022 Oct 1;187(4):593-605. Epub 2022 Sep 19 doi: 10.1530/EJE-22-0440. PMID: 36018781Free PMC Article
Update on the clinical management of multiple endocrine neoplasia type 1.
Pieterman CRC, Valk GD
Clin Endocrinol (Oxf) 2022 Oct;97(4):409-423. Epub 2022 Apr 1 doi: 10.1111/cen.14727. PMID: 35319130Free PMC Article
Pathology of prolactinomas: any predictive value?
Lopes MBS
Pituitary 2020 Feb;23(1):3-8. doi: 10.1007/s11102-019-00997-1. PMID: 31641970
Cushing's disease.
De Martin M, Pecori Giraldi F, Cavagnini F
Pituitary 2006;9(4):279-87. doi: 10.1007/s11102-006-0407-6. PMID: 17077950
Cushing's syndrome.
Howlett TA, Rees LH, Besser GM
Clin Endocrinol Metab 1985 Nov;14(4):911-45. doi: 10.1016/s0300-595x(85)80083-9. PMID: 3002679

Clinical prediction guides

Diagnosis and Management of Pituitary Adenomas: A Review.
Tritos NA, Miller KK
JAMA 2023 Apr 25;329(16):1386-1398. doi: 10.1001/jama.2023.5444. PMID: 37097352
Aggressive pituitary tumours and carcinomas, characteristics and management of 171 patients.
Burman P, Trouillas J, Losa M, McCormack A, Petersenn S, Popovic V, Theodoropoulou M, Raverot G, Dekkers OM; ESE survey collaborators †
Eur J Endocrinol 2022 Oct 1;187(4):593-605. Epub 2022 Sep 19 doi: 10.1530/EJE-22-0440. PMID: 36018781Free PMC Article
Update on the clinical management of multiple endocrine neoplasia type 1.
Pieterman CRC, Valk GD
Clin Endocrinol (Oxf) 2022 Oct;97(4):409-423. Epub 2022 Apr 1 doi: 10.1111/cen.14727. PMID: 35319130Free PMC Article
Diagnosis and Treatment of Pituitary Adenomas: A Review.
Molitch ME
JAMA 2017 Feb 7;317(5):516-524. doi: 10.1001/jama.2016.19699. PMID: 28170483
Silent corticotroph adenomas.
Karavitaki N, Ansorge O, Wass JA
Arq Bras Endocrinol Metabol 2007 Nov;51(8):1314-8. doi: 10.1590/s0004-27302007000800017. PMID: 18209869

Recent systematic reviews

Natural History of Non-Functioning Pituitary Adenomas: A Systematic Review and Meta-Analysis.
Rikvold SD, Pedersen MB, Andreassen M, Krogh J
Horm Metab Res 2023 Jul;55(7):443-451. Epub 2023 Jul 10 doi: 10.1055/a-2096-1340. PMID: 37494058
Fluorescence-guided detection of pituitary neuroendocrine tumor (PitNET) tissue during endoscopic transsphenoidal surgery available agents, their potential, and technical aspects.
Vergeer RA, Theunissen REP, van Elk T, Schmidt I, Postma MR, Tamasi K, van Dijk JMC, Kuijlen JMA
Rev Endocr Metab Disord 2022 Jun;23(3):647-657. Epub 2022 Mar 28 doi: 10.1007/s11154-022-09718-9. PMID: 35344185Free PMC Article
Plurihormonal ACTH-GH Pituitary Adenoma: Case Report and Systematic Literature Review.
Roca E, Mattogno PP, Porcelli T, Poliani L, Belotti F, Schreiber A, Maffezzoni F, Fontanella MM, Doglietto F
World Neurosurg 2018 Jun;114:e158-e164. Epub 2018 Mar 6 doi: 10.1016/j.wneu.2018.02.120. PMID: 29501516
Metabolic In Vivo Visualization of Pituitary Adenomas: a Systematic Review of Imaging Modalities.
Yao A, Balchandani P, Shrivastava RK
World Neurosurg 2017 Aug;104:489-498. Epub 2017 Apr 28 doi: 10.1016/j.wneu.2017.04.128. PMID: 28461279Free PMC Article
Natural history of nonfunctioning pituitary adenomas and incidentalomas: a systematic review and metaanalysis.
Fernández-Balsells MM, Murad MH, Barwise A, Gallegos-Orozco JF, Paul A, Lane MA, Lampropulos JF, Natividad I, Perestelo-Pérez L, Ponce de León-Lovatón PG, Erwin PJ, Carey J, Montori VM
J Clin Endocrinol Metab 2011 Apr;96(4):905-12. doi: 10.1210/jc.2010-1054. PMID: 21474687

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