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Breast Paget Disease without Invasive Carcinoma

MedGen UID:
311101
Concept ID:
C1709447
Neoplastic Process
Synonyms: Paget Disease of the Breast without Invasive Carcinoma; Paget's Disease of the Breast without Invasive Carcinoma; Tis (Paget)

Definition

Paget disease involving the skin overlying the mammary gland, without accompanying invasive ductal or lobular breast carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBreast Paget Disease without Invasive Carcinoma

Professional guidelines

PubMed

Gradishar WJ, Moran MS, Abraham J, Abramson V, Aft R, Agnese D, Allison KH, Anderson B, Bailey J, Burstein HJ, Chen N, Chew H, Dang C, Elias AD, Giordano SH, Goetz MP, Jankowitz RC, Javid SH, Krishnamurthy J, Leitch AM, Lyons J, McCloskey S, McShane M, Mortimer J, Patel SA, Rosenberger LH, Rugo HS, Santa-Maria C, Schneider BP, Smith ML, Soliman H, Stringer-Reasor EM, Telli ML, Wei M, Wisinski KB, Yeung KT, Young JS, Schonfeld R, Kumar R
J Natl Compr Canc Netw 2024 Jul;22(5):331-357. doi: 10.6004/jnccn.2024.0035. PMID: 39019058
Hudson-Phillips S, Cox K, Patel P, Al Sarakbi W
Br J Hosp Med (Lond) 2023 Jan 2;84(1):1-8. Epub 2023 Jan 24 doi: 10.12968/hmed.2022.0439. PMID: 36708338
Gradishar WJ, Moran MS, Abraham J, Aft R, Agnese D, Allison KH, Anderson B, Burstein HJ, Chew H, Dang C, Elias AD, Giordano SH, Goetz MP, Goldstein LJ, Hurvitz SA, Isakoff SJ, Jankowitz RC, Javid SH, Krishnamurthy J, Leitch M, Lyons J, Mortimer J, Patel SA, Pierce LJ, Rosenberger LH, Rugo HS, Sitapati A, Smith KL, Smith ML, Soliman H, Stringer-Reasor EM, Telli ML, Ward JH, Wisinski KB, Young JS, Burns J, Kumar R
J Natl Compr Canc Netw 2022 Jun;20(6):691-722. doi: 10.6004/jnccn.2022.0030. PMID: 35714673

Recent clinical studies

Etiology

Mousa-Doust D, Warburton R, Pao JS, Dingee C, Bazzarelli A, Newman-Bremang J, McKevitt E
Am J Surg 2024 May;231:18-23. Epub 2024 Jan 25 doi: 10.1016/j.amjsurg.2024.01.026. PMID: 38641371
Lin CW, Chiang MH, Tam KW
Int J Surg 2022 Nov;107:106964. Epub 2022 Oct 26 doi: 10.1016/j.ijsu.2022.106964. PMID: 36309195
Brunt AM, Haviland JS, Sydenham M, Agrawal RK, Algurafi H, Alhasso A, Barrett-Lee P, Bliss P, Bloomfield D, Bowen J, Donovan E, Goodman A, Harnett A, Hogg M, Kumar S, Passant H, Quigley M, Sherwin L, Stewart A, Syndikus I, Tremlett J, Tsang Y, Venables K, Wheatley D, Bliss JM, Yarnold JR
J Clin Oncol 2020 Oct 1;38(28):3261-3272. Epub 2020 Jul 14 doi: 10.1200/JCO.19.02750. PMID: 32663119Free PMC Article
Adams SJ, Kanthan R
Breast 2016 Oct;29:14-23. Epub 2016 Jul 6 doi: 10.1016/j.breast.2016.06.015. PMID: 27394005
Berg JW, Hutter RV
Cancer 1995 Jan 1;75(1 Suppl):257-69. doi: 10.1002/1097-0142(19950101)75:1+<257::aid-cncr2820751311>3.0.co;2-y. PMID: 8001000

Diagnosis

Gradishar WJ, Moran MS, Abraham J, Abramson V, Aft R, Agnese D, Allison KH, Anderson B, Bailey J, Burstein HJ, Chen N, Chew H, Dang C, Elias AD, Giordano SH, Goetz MP, Jankowitz RC, Javid SH, Krishnamurthy J, Leitch AM, Lyons J, McCloskey S, McShane M, Mortimer J, Patel SA, Rosenberger LH, Rugo HS, Santa-Maria C, Schneider BP, Smith ML, Soliman H, Stringer-Reasor EM, Telli ML, Wei M, Wisinski KB, Yeung KT, Young JS, Schonfeld R, Kumar R
J Natl Compr Canc Netw 2024 Jul;22(5):331-357. doi: 10.6004/jnccn.2024.0035. PMID: 39019058
Hudson-Phillips S, Cox K, Patel P, Al Sarakbi W
Br J Hosp Med (Lond) 2023 Jan 2;84(1):1-8. Epub 2023 Jan 24 doi: 10.12968/hmed.2022.0439. PMID: 36708338
Lyons D, Wahab RA, Vijapura C, Mahoney MC
Clin Radiol 2021 Mar;76(3):172-184. Epub 2020 Oct 17 doi: 10.1016/j.crad.2020.09.013. PMID: 33077158
Gilmore R, Prasath V, Habibi M
Adv Exp Med Biol 2020;1252:133-136. doi: 10.1007/978-3-030-41596-9_18. PMID: 32816273
Chiorean A, Pintican RM, Szep M, Feier D, Rogojan L, Fetica B, Dindelegan G, Vlad B, Duma M
Korean J Radiol 2020 Aug;21(8):955-966. doi: 10.3348/kjr.2019.0831. PMID: 32677380Free PMC Article

Therapy

Borella F, Preti M, Vieira-Baptista P, Pérez-López FR, Bertero L, Gallio N, Micheletti L, Benedetto C
Maturitas 2022 Sep;163:23-27. Epub 2022 May 27 doi: 10.1016/j.maturitas.2022.05.010. PMID: 35661559
van der Linden M, van Hees CL, van Beurden M, Bulten J, van Dorst EB, Esajas MD, Meeuwis KA, Boll D, van Poelgeest MI, de Hullu JA
Am J Obstet Gynecol 2022 Aug;227(2):250.e1-250.e8. Epub 2022 Apr 18 doi: 10.1016/j.ajog.2022.04.012. PMID: 35447145
Brunt AM, Haviland JS, Sydenham M, Agrawal RK, Algurafi H, Alhasso A, Barrett-Lee P, Bliss P, Bloomfield D, Bowen J, Donovan E, Goodman A, Harnett A, Hogg M, Kumar S, Passant H, Quigley M, Sherwin L, Stewart A, Syndikus I, Tremlett J, Tsang Y, Venables K, Wheatley D, Bliss JM, Yarnold JR
J Clin Oncol 2020 Oct 1;38(28):3261-3272. Epub 2020 Jul 14 doi: 10.1200/JCO.19.02750. PMID: 32663119Free PMC Article
Edey KA, Allan E, Murdoch JB, Cooper S, Bryant A
Cochrane Database Syst Rev 2013 Oct 26;(10):CD009245. doi: 10.1002/14651858.CD009245.pub2. PMID: 24163070
Nardelli AA, Stafinski T, Menon D
BMC Dermatol 2011 Jun 15;11:13. doi: 10.1186/1471-5945-11-13. PMID: 21676258Free PMC Article

Prognosis

Lin CW, Chiang MH, Tam KW
Int J Surg 2022 Nov;107:106964. Epub 2022 Oct 26 doi: 10.1016/j.ijsu.2022.106964. PMID: 36309195
Plutino FM, Del Medico P, Vescio G, Fava MG
Ann Ital Chir 2022 May 5;11 PMID: 35588206
Hutchings D, Windon A, Assarzadegan N, Salimian KJ, Voltaggio L, Montgomery EA
Histopathology 2021 Jan;78(2):276-280. Epub 2020 Sep 23 doi: 10.1111/his.14218. PMID: 32705713Free PMC Article
Brunt AM, Haviland JS, Sydenham M, Agrawal RK, Algurafi H, Alhasso A, Barrett-Lee P, Bliss P, Bloomfield D, Bowen J, Donovan E, Goodman A, Harnett A, Hogg M, Kumar S, Passant H, Quigley M, Sherwin L, Stewart A, Syndikus I, Tremlett J, Tsang Y, Venables K, Wheatley D, Bliss JM, Yarnold JR
J Clin Oncol 2020 Oct 1;38(28):3261-3272. Epub 2020 Jul 14 doi: 10.1200/JCO.19.02750. PMID: 32663119Free PMC Article
Berg JW, Hutter RV
Cancer 1995 Jan 1;75(1 Suppl):257-69. doi: 10.1002/1097-0142(19950101)75:1+<257::aid-cncr2820751311>3.0.co;2-y. PMID: 8001000

Clinical prediction guides

Cook EE, Harrison BT, Hirsch MS
Histopathology 2023 Jul;83(1):104-108. Epub 2023 Mar 27 doi: 10.1111/his.14908. PMID: 36971374
Lin CW, Chiang MH, Tam KW
Int J Surg 2022 Nov;107:106964. Epub 2022 Oct 26 doi: 10.1016/j.ijsu.2022.106964. PMID: 36309195
van der Linden M, van Hees CL, van Beurden M, Bulten J, van Dorst EB, Esajas MD, Meeuwis KA, Boll D, van Poelgeest MI, de Hullu JA
Am J Obstet Gynecol 2022 Aug;227(2):250.e1-250.e8. Epub 2022 Apr 18 doi: 10.1016/j.ajog.2022.04.012. PMID: 35447145
Kilts TP, Long B, Glasgow AE, Bakkum-Gamez JN, Habermann EB, Cliby WA
Gynecol Oncol 2020 Jun;157(3):649-655. Epub 2020 Apr 5 doi: 10.1016/j.ygyno.2020.03.018. PMID: 32268952
Furukawa F, Takigawa M, Matsuyoshi N, Shirahama S, Wakita H, Fujita M, Horiguchi Y, Imamura S
J Dermatol 1994 Nov;21(11):802-13. doi: 10.1111/j.1346-8138.1994.tb03294.x. PMID: 7852640

Recent systematic reviews

Lin CW, Chiang MH, Tam KW
Int J Surg 2022 Nov;107:106964. Epub 2022 Oct 26 doi: 10.1016/j.ijsu.2022.106964. PMID: 36309195
Adams SJ, Kanthan R
Breast 2016 Oct;29:14-23. Epub 2016 Jul 6 doi: 10.1016/j.breast.2016.06.015. PMID: 27394005
Edey KA, Allan E, Murdoch JB, Cooper S, Bryant A
Cochrane Database Syst Rev 2013 Oct 26;(10):CD009245. doi: 10.1002/14651858.CD009245.pub2. PMID: 24163070
Nardelli AA, Stafinski T, Menon D
BMC Dermatol 2011 Jun 15;11:13. doi: 10.1186/1471-5945-11-13. PMID: 21676258Free PMC Article

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