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Clonal BCL6 Gene Rearrangement

MedGen UID:
309014
Concept ID:
C1516666
Cell or Molecular Dysfunction
Synonyms: Clonal BCL-6 Gene Rearrangement; Monoclonal BCL-6 Gene Rearrangement

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVClonal BCL6 Gene Rearrangement

Professional guidelines

PubMed

Choi JS, Nam DH, Ko YH, Seo JW, Choi YL, Suh YL, Ree HJ
Am J Surg Pathol 2003 Jul;27(7):919-28. doi: 10.1097/00000478-200307000-00007. PMID: 12826884

Recent clinical studies

Etiology

Saksena A, Jain A, Pack SD, Kim J, Lee I, Tyagi M, Xi L, Pittaluga S, Raffeld M, Jaffe ES
Am J Surg Pathol 2023 Mar 1;47(3):409-419. Epub 2022 Dec 1 doi: 10.1097/PAS.0000000000002003. PMID: 36461146Free PMC Article
Trecourt A, Mauduit C, Szablewski V, Fontaine J, Balme B, Donzel M, Laurent C, Sesques P, Ghesquières H, Bachy E, Salles G, Emile JF, Chassagne-Clément C, Genestier L, Copie-Bergman C, Traverse-Glehen A
Am J Surg Pathol 2022 Jan 1;46(1):58-70. doi: 10.1097/PAS.0000000000001780. PMID: 34265801
Ganapathi KA, Brown LE, Prakash S, Bhargava P
Pathology 2021 Apr;53(3):349-366. Epub 2021 Mar 5 doi: 10.1016/j.pathol.2021.01.002. PMID: 33685720
Nador RG, Chadburn A, Gundappa G, Cesarman E, Said JW, Knowles DM
Am J Surg Pathol 2003 Mar;27(3):293-302. doi: 10.1097/00000478-200303000-00002. PMID: 12604885
Neri A, Fracchiolla NS, Roscetti E, Garatti S, Trecca D, Boletini A, Perletti L, Baldini L, Maiolo AT, Berti E
Blood 1995 Oct 15;86(8):3160-72. PMID: 7579411

Diagnosis

Ganapathi KA, Brown LE, Prakash S, Bhargava P
Pathology 2021 Apr;53(3):349-366. Epub 2021 Mar 5 doi: 10.1016/j.pathol.2021.01.002. PMID: 33685720
Boiza-Sánchez M, Manso R, Balagué O, Chamizo C, Askari E, Salgado RN, Blas-López C, Aguirregoicoa-García E, Menárguez J, Santonja C, Adrados M, Limeres-González MÁ, Piris MÁ, Rodríguez-Pinilla SM
PLoS One 2020;15(11):e0241634. Epub 2020 Nov 12 doi: 10.1371/journal.pone.0241634. PMID: 33180881Free PMC Article
Oishi N, Sartori-Valinotti JC, Bennani NN, Wada DA, He R, Cappel MA, Feldman AL
J Cutan Pathol 2019 Sep;46(9):637-644. Epub 2019 May 3 doi: 10.1111/cup.13475. PMID: 30980412
Nakamura N, Abe M
Pathol Int 2003 Apr;53(4):195-203. doi: 10.1046/j.1320-5463.2003.01455.x. PMID: 12675762
Lust JA
J Clin Lab Anal 1996;10(6):359-67. doi: 10.1002/(SICI)1098-2825(1996)10:6<359::AID-JCLA7>3.0.CO;2-1. PMID: 8951602

Therapy

Oishi N, Sartori-Valinotti JC, Bennani NN, Wada DA, He R, Cappel MA, Feldman AL
J Cutan Pathol 2019 Sep;46(9):637-644. Epub 2019 May 3 doi: 10.1111/cup.13475. PMID: 30980412
Moroch J, Copie-Bergman C, de Leval L, Plonquet A, Martin-Garcia N, Delfau-Larue MH, Molinier-Frenkel V, Belhadj K, Haioun C, Audouin J, Swerdlow SH, Marafioti T, Gaulard P
Am J Surg Pathol 2012 Nov;36(11):1636-46. doi: 10.1097/PAS.0b013e318268d9ff. PMID: 23073322
Sarro R, Fiche M, Bisig B, Ketterer N, Benhattar J, Achtari C, de Leval L
Int J Gynecol Pathol 2012 May;31(3):236-41. doi: 10.1097/PGP.0b013e31823b6f6a. PMID: 22498940
Sevilla DW, Murty VV, Sun XL, Nandula SV, Mansukhani MM, Alobeid B, Bhagat G
Hematol Oncol 2011 Jun;29(2):81-90. Epub 2010 Aug 5 doi: 10.1002/hon.958. PMID: 20687199
Vakiani E, Basso K, Klein U, Mansukhani MM, Narayan G, Smith PM, Murty VV, Dalla-Favera R, Pasqualucci L, Bhagat G
Hematol Oncol 2008 Dec;26(4):199-211. doi: 10.1002/hon.859. PMID: 18457340

Prognosis

Yan X, Chen B, Jing H, Yang Z, Zhang T, Lin Y, Shi J
J Hematop 2023 Dec;16(4):235-240. Epub 2023 Nov 27 doi: 10.1007/s12308-023-00566-3. PMID: 38175437
Rodríguez Pinilla SM, Roncador G, Rodríguez-Peralto JL, Mollejo M, García JF, Montes-Moreno S, Camacho FI, Ortiz P, Limeres-González MA, Torres A, Campo E, Navarro-Conde P, Piris MA
Am J Surg Pathol 2009 Jan;33(1):81-90. doi: 10.1097/PAS.0b013e31818e52fe. PMID: 18987541
Rodríguez-Pinilla SM, Atienza L, Murillo C, Pérez-Rodríguez A, Montes-Moreno S, Roncador G, Pérez-Seoane C, Domínguez P, Camacho FI, Piris MA
Am J Surg Pathol 2008 Dec;32(12):1787-99. doi: 10.1097/PAS.0b013e31817f123e. PMID: 18779728
Cho-Vega JH, Vega F, Rassidakis G, Medeiros LJ
Am J Clin Pathol 2006 Jun;125 Suppl:S38-49. doi: 10.1309/CVFYBQNMX1PKNAA7. PMID: 16830956
Akasaka T, Lossos IS, Levy R
Blood 2003 Aug 15;102(4):1443-8. Epub 2003 May 8 doi: 10.1182/blood-2002-08-2482. PMID: 12738680

Clinical prediction guides

Vakiani E, Basso K, Klein U, Mansukhani MM, Narayan G, Smith PM, Murty VV, Dalla-Favera R, Pasqualucci L, Bhagat G
Hematol Oncol 2008 Dec;26(4):199-211. doi: 10.1002/hon.859. PMID: 18457340
Akasaka T, Lossos IS, Levy R
Blood 2003 Aug 15;102(4):1443-8. Epub 2003 May 8 doi: 10.1182/blood-2002-08-2482. PMID: 12738680
Jardin F, Gaulard P, Buchonnet G, Contentin N, Leprêtre S, Lenain P, Stamatoullas A, Picquenot JM, Duval C, Parmentier F, Tilly H, Bastard C
Leukemia 2002 Nov;16(11):2309-17. doi: 10.1038/sj.leu.2402707. PMID: 12399977
Franke S, Wlodarska I, Maes B, Vandenberghe P, Delabie J, Hagemeijer A, De Wolf-Peeters C
Blood 2001 Mar 15;97(6):1845-53. doi: 10.1182/blood.v97.6.1845. PMID: 11238128
Neri A, Fracchiolla NS, Roscetti E, Garatti S, Trecca D, Boletini A, Perletti L, Baldini L, Maiolo AT, Berti E
Blood 1995 Oct 15;86(8):3160-72. PMID: 7579411

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