del(6q21)

MedGen UID:: 273707
•Concept ID:: C1515601
•: Cell or Molecular Dysfunction

Synonym:

del(6)(q21)

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVdel(6q21)

Molecular Abnormality
- Cytogenetic Abnormality
  - Chromosomal Rearrangement
    - Chromosomal Deletion
      - del(6q21)

Recent clinical studies

Etiology

Role of cytogenetic abnormalities detected by fluorescence in situ hybridization as a prognostic marker: Pathogenesis & clinical course in patients with B-chronic lymphocytic leukaemia.

Shetty D, Jain H, Rohil Y, Khattry N, Sengar M, Bagal B, Jain H, Gokarn A, Punatar S, Avinash Bonda VN, Subramanian PG
Indian J Med Res 2021 Apr;153(4):475-483. doi: 10.4103/ijmr.IJMR_2257_18. PMID: 34380794 Free PMC Article

Clinico-pathological impact of cytogenetic subgroups in B-cell chronic lymphocytic leukemia: experience from India.

Amare PS, Gadage V, Jain H, Nikalje S, Manju S, Mittal N, Gujral S, Nair R
Indian J Cancer 2013 Jul-Sep;50(3):261-7. doi: 10.4103/0019-509X.118730. PMID: 24061469

Cytogenetic and molecular aberrations of multiple myeloma patients: a single-center study in Singapore.

Lim AS, Lim TH, See KH, Ng YJ, Tan YM, Choo NS, Lim SX, Yee Y, Lau LC, Tien SL, Sathish K, Tan DC
Chin Med J (Engl) 2013;126(10):1872-7. PMID: 23673102

Clonal evolution in chronic lymphocytic leukemia: acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival.

Stilgenbauer S, Sander S, Bullinger L, Benner A, Leupolt E, Winkler D, Kröber A, Kienle D, Lichter P, Döhner H
Haematologica 2007 Sep;92(9):1242-5. Epub 2007 Aug 1 doi: 10.3324/haematol.10720. PMID: 17666364

See all (4)

Diagnosis

Role of cytogenetic abnormalities detected by fluorescence in situ hybridization as a prognostic marker: Pathogenesis & clinical course in patients with B-chronic lymphocytic leukaemia.

Cytogenetic and molecular aberrations of multiple myeloma patients: a single-center study in Singapore.

Lim AS, Lim TH, See KH, Ng YJ, Tan YM, Choo NS, Lim SX, Yee Y, Lau LC, Tien SL, Sathish K, Tan DC
Chin Med J (Engl) 2013;126(10):1872-7. PMID: 23673102

See all (2)