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Cervicomedullary junction neoplasm

MedGen UID:
272453
•Concept ID:
C1332923
•
Neoplastic Process
Synonyms: Cervicomedullary Junction Neoplasm; cervicomedullary junction neoplasm; Cervicomedullary Junction Neoplasms; cervicomedullary junction neoplasms; Cervicomedullary Junction Tumor; cervicomedullary junction tumor; cervicomedullary junction tumour; Neoplasm of Cervicomedullary Junction; neoplasm of cervicomedullary junction; Neoplasm of the Cervicomedullary Junction; neoplasm of the cervicomedullary junction; Tumor of Cervicomedullary Junction; tumor of cervicomedullary junction; Tumor of the Cervicomedullary Junction; tumor of the cervicomedullary junction; tumour of cervicomedullary junction; tumour of the cervicomedullary junction
 
Monarch Initiative: MONDO:0003108

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCervicomedullary junction neoplasm

Professional guidelines

PubMed

Intra-axial tumors of the medullocervical junction: diagnosis and microsurgical treatment.
Xu Q, Bao W, Mao R, Pang L
Chin Med J (Engl) 1998 Nov;111(11):968-71. PMID: 11189220

Recent clinical studies

Etiology

Stereotactic Radiosurgery for Cranial and Spinal Hemangioblastomas: A Single-Institution Retrospective Series.
Yoo KH, Park DJ, Marianayagam NJ, Gu X, Pollom EL, Soltys SG, Chang SD, Meola A
Neurosurgery 2024 Mar 1;94(3):630-642. Epub 2023 Oct 17 doi: 10.1227/neu.0000000000002728. PMID: 37967154
Rhombencephalitis and longitudinal extensive myelitis associated with dinutuximab use in high-risk neuroblastoma.
Atak F, Aydın GB, Öncel İ, Öz S, Oğuz KK
Turk J Pediatr 2023;65(3):523-530. doi: 10.24953/turkjped.2022.598. PMID: 37395971
Spinal involvement in pediatric familial cavernous malformation syndrome.
Geraldo AF, Luis A, Alves CAPF, Tortora D, Guimarães J, Reimão S, Pavanello M, de Marco P, Scala M, Capra V, Rossi A, Schwartz ES, Mankad K, Severino M
Neuroradiology 2022 Aug;64(8):1671-1679. Epub 2022 Apr 22 doi: 10.1007/s00234-022-02958-1. PMID: 35451625
Outcome Features Analysis in Intramedullary Tumors of the Cervicomedullary Junction: A Surgical Series.
Tariciotti L, Brunetto GMF, Landi A, Gregori F, Santoro F, Frati A, Delfini R, Santoro A
J Neurol Surg A Cent Eur Neurosurg 2021 May;82(3):225-231. Epub 2021 Feb 4 doi: 10.1055/s-0040-1719080. PMID: 33540453
Intramedullary hemangioblastomas: surgical results in 16 patients.
Joaquim AF, Ghizoni E, dos Santos MJ, Valadares MG, da Silva FS, Tedeschi H
Neurosurg Focus 2015 Aug;39(2):E18. doi: 10.3171/2015.5.FOCUS15171. PMID: 26235016

Diagnosis

Stereotactic Radiosurgery for Cranial and Spinal Hemangioblastomas: A Single-Institution Retrospective Series.
Yoo KH, Park DJ, Marianayagam NJ, Gu X, Pollom EL, Soltys SG, Chang SD, Meola A
Neurosurgery 2024 Mar 1;94(3):630-642. Epub 2023 Oct 17 doi: 10.1227/neu.0000000000002728. PMID: 37967154
Giant Cell Ependymoma of Cervicomedullary Junction: A Case Report of a Long-Term Survivor and Literature Review.
Cappelletti M, Ruggeri AG, Iacopino G, Delfini R
World Neurosurg 2018 Aug;116:121-126. Epub 2018 May 14 doi: 10.1016/j.wneu.2018.05.040. PMID: 29772366
Ganglioglioma of brain stem and cervicomedullary junction: A 50years review of literature.
Janjua MB, Ivasyk I, Pisapia DJ, Souweidane MM
J Clin Neurosci 2017 Oct;44:34-46. Epub 2017 Jul 4 doi: 10.1016/j.jocn.2017.06.021. PMID: 28687443
Calcifying Pseudoneoplasm of the Cervicomedullary Junction: Case Report and a Literature Review.
Alshareef M, Vargas J, Welsh CT, Kalhorn SP
World Neurosurg 2016 Jan;85:364.e11-8. Epub 2015 Sep 1 doi: 10.1016/j.wneu.2015.08.055. PMID: 26341436
MR imaging of the craniovertebral junction.
Smoker WR
Magn Reson Imaging Clin N Am 2000 Aug;8(3):635-50. PMID: 10947931

Therapy

Stereotactic Radiosurgery for Cranial and Spinal Hemangioblastomas: A Single-Institution Retrospective Series.
Yoo KH, Park DJ, Marianayagam NJ, Gu X, Pollom EL, Soltys SG, Chang SD, Meola A
Neurosurgery 2024 Mar 1;94(3):630-642. Epub 2023 Oct 17 doi: 10.1227/neu.0000000000002728. PMID: 37967154
Rhombencephalitis and longitudinal extensive myelitis associated with dinutuximab use in high-risk neuroblastoma.
Atak F, Aydın GB, Öncel İ, Öz S, Oğuz KK
Turk J Pediatr 2023;65(3):523-530. doi: 10.24953/turkjped.2022.598. PMID: 37395971
Brain-stem hemangioblastomas: The seemingly innocuous lesion in a perilous location.
Joseph J, Behari S, Gupta S, Bhaisora KS, Gandhi A, Srivastava A, Jaiswal AK
Neurol India 2018 May-Jun;66(3):779-796. doi: 10.4103/0028-3886.232294. PMID: 29766943
Endoscopic endonasal transclival transodontoid approach for ventral decompression of the craniovertebral junction: operative technique and nuances.
Liu JK, Patel J, Goldstein IM, Eloy JA
Neurosurg Focus 2015 Apr;38(4):E17. doi: 10.3171/2015.1.FOCUS14813. PMID: 25828493
Advances toward an understanding of brainstem gliomas.
Donaldson SS, Laningham F, Fisher PG
J Clin Oncol 2006 Mar 10;24(8):1266-72. doi: 10.1200/JCO.2005.04.6599. PMID: 16525181

Prognosis

Stereotactic Radiosurgery for Cranial and Spinal Hemangioblastomas: A Single-Institution Retrospective Series.
Yoo KH, Park DJ, Marianayagam NJ, Gu X, Pollom EL, Soltys SG, Chang SD, Meola A
Neurosurgery 2024 Mar 1;94(3):630-642. Epub 2023 Oct 17 doi: 10.1227/neu.0000000000002728. PMID: 37967154
Myopericytoma at the Craniocervical Junction: Clinicopathological Report and Review of a Rare Perivascular Neoplasm.
Yang JC, Venteicher AS, Koch MJ, Stapleton CJ, Friedman GN, Venteicher EM, Shin JH
Neurosurgery 2019 Aug 1;85(2):E360-E365. doi: 10.1093/neuros/nyy262. PMID: 29889275
Giant Cell Ependymoma of Cervicomedullary Junction: A Case Report of a Long-Term Survivor and Literature Review.
Cappelletti M, Ruggeri AG, Iacopino G, Delfini R
World Neurosurg 2018 Aug;116:121-126. Epub 2018 May 14 doi: 10.1016/j.wneu.2018.05.040. PMID: 29772366
Calcifying Pseudoneoplasm of the Cervicomedullary Junction: Case Report and a Literature Review.
Alshareef M, Vargas J, Welsh CT, Kalhorn SP
World Neurosurg 2016 Jan;85:364.e11-8. Epub 2015 Sep 1 doi: 10.1016/j.wneu.2015.08.055. PMID: 26341436
Surgical management of torticollis.
Maxwell RE
Postgrad Med 1984 May 15;75(7):147-52, 154-5. doi: 10.1080/00325481.1984.11698625. PMID: 6718289

Clinical prediction guides

Rhombencephalitis and longitudinal extensive myelitis associated with dinutuximab use in high-risk neuroblastoma.
Atak F, Aydın GB, Öncel İ, Öz S, Oğuz KK
Turk J Pediatr 2023;65(3):523-530. doi: 10.24953/turkjped.2022.598. PMID: 37395971
Progressive motor impairment from "critical" demyelinating lesions of the cervicomedullary junction.
Jackson-Tarlton CS, Flanagan EP, Messina SA, Barakat B, Ahmad R, Kantarci OH, Weinshenker BG, Keegan BM
Mult Scler 2023 Jan;29(1):74-80. Epub 2022 Aug 24 doi: 10.1177/13524585221114438. PMID: 36000479
Spinal involvement in pediatric familial cavernous malformation syndrome.
Geraldo AF, Luis A, Alves CAPF, Tortora D, Guimarães J, Reimão S, Pavanello M, de Marco P, Scala M, Capra V, Rossi A, Schwartz ES, Mankad K, Severino M
Neuroradiology 2022 Aug;64(8):1671-1679. Epub 2022 Apr 22 doi: 10.1007/s00234-022-02958-1. PMID: 35451625
Multiple sclerosis, solitary sclerosis or something else?
Lattanzi S, Logullo F, Di Bella P, Silvestrini M, Provinciali L
Mult Scler 2014 Dec;20(14):1819-24. Epub 2014 May 22 doi: 10.1177/1352458514535129. PMID: 24852918
Intra-axial tumors of the cervicomedullary junction: surgical results and long-term outcome.
Weiner HL, Freed D, Woo HH, Rezai AR, Kim R, Epstein FJ
Pediatr Neurosurg 1997 Jul;27(1):12-8. doi: 10.1159/000121219. PMID: 9486831

Recent systematic reviews

A rare condition: Spontaneous subarachnoid haemorrhage due to spinal hemangioblastoma: Report of 2 cases and review of the literature.
Tuleasca C, Knafo S, David P, Richard S, Adam C, Aghakhani N, Parker F
Neurochirurgie 2020 Nov;66(5):359-364. Epub 2020 Aug 28 doi: 10.1016/j.neuchi.2020.05.008. PMID: 32866499

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