U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Benign Extraskeletal Cartilaginous and Osseous Neoplasm

MedGen UID:
272357
•Concept ID:
C1332499
•
Neoplastic Process
Synonym: Benign Extraskeletal Cartilaginous and Osseous Tumor

Definition

A benign mesenchymal neoplasm with cartilaginous or osseous differentiation arising from the soft tissues exclusively. Representative examples include chondroma and osteoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign Extraskeletal Cartilaginous and Osseous Neoplasm

Recent clinical studies

Etiology

Immunocytochemical identification of osteogenic bone tumors by osteonectin antibodies.
Jundt G, Schulz A, Berghäuser KH, Fisher LW, Gehron-Robey P, Termine JD
Virchows Arch A Pathol Anat Histopathol 1989;414(4):345-53. doi: 10.1007/BF00734090. PMID: 2496522

Diagnosis

GRM1 Immunohistochemistry Distinguishes Chondromyxoid Fibroma From its Histologic Mimics.
Toland AMS, Lam SW, Varma S, Wang A, Howitt BE, Kunder CA, Kerr DA, Szuhai K, Bovée JVMG, Charville GW
Am J Surg Pathol 2022 Oct 1;46(10):1407-1414. Epub 2022 Jun 1 doi: 10.1097/PAS.0000000000001921. PMID: 35650682Free PMC Article
Immunohistochemical and FISH analysis of MDM2 and CDK4 in a dedifferentiated extraskeletal osteosarcoma arising in the vastus lateralis muscle: differential diagnosis and diagnostic algorithm.
von Baer A, Ehrhardt A, Baumhoer D, Mayer-Steinacker R, Schultheiss M, Abdul-Nou T, Mentzel T, Fend F, Möller P, Jundt G, Barth TF
Pathol Res Pract 2014 Oct;210(10):698-703. Epub 2014 May 22 doi: 10.1016/j.prp.2014.05.010. PMID: 24974983
A large extraskeletal osteochondroma of the foot.
Estil JC Jr, Yeo ED, Kim HJ, Cho WT, Lee JJ
J Foot Ankle Surg 2013 Sep-Oct;52(5):663-5. Epub 2013 May 2 doi: 10.1053/j.jfas.2013.03.028. PMID: 23643667
Extraskeletal osteosarcoma histologically mimicking parosteal osteosarcoma.
Fukunaga M
Pathol Int 2002 Jul;52(7):492-6. doi: 10.1046/j.1440-1827.2002.01372.x. PMID: 12167110
From the archives of the AFIP. Extraskeletal osseous and cartilaginous tumors of the extremities.
Kransdorf MJ, Meis JM
Radiographics 1993 Jul;13(4):853-84. doi: 10.1148/radiographics.13.4.8356273. PMID: 8356273

Prognosis

February 2003: a 53-year-old male with new onset seizures.
Omalu BI, Wiley CA, Hamilton RL
Brain Pathol 2003 Jul;13(3):419-20, 423. PMID: 12946032
Malignant cartilaginous tumors of the mediastinum: clinicopathological study of six cases presenting as extraskeletal soft tissue masses.
Suster S, Moran CA
Hum Pathol 1997 May;28(5):588-94. doi: 10.1016/s0046-8177(97)90081-2. PMID: 9158707

Clinical prediction guides

GRM1 Immunohistochemistry Distinguishes Chondromyxoid Fibroma From its Histologic Mimics.
Toland AMS, Lam SW, Varma S, Wang A, Howitt BE, Kunder CA, Kerr DA, Szuhai K, Bovée JVMG, Charville GW
Am J Surg Pathol 2022 Oct 1;46(10):1407-1414. Epub 2022 Jun 1 doi: 10.1097/PAS.0000000000001921. PMID: 35650682Free PMC Article
Reappraisal of mesenchymal chondrosarcoma: novel morphologic observations of the hyaline cartilage and endochondral ossification and beta-catenin, Sox9, and osteocalcin immunostaining of 22 cases.
Fanburg-Smith JC, Auerbach A, Marwaha JS, Wang Z, Rushing EJ
Hum Pathol 2010 May;41(5):653-62. doi: 10.1016/j.humpath.2009.11.006. PMID: 20138330
Malignant cartilaginous tumors of the mediastinum: clinicopathological study of six cases presenting as extraskeletal soft tissue masses.
Suster S, Moran CA
Hum Pathol 1997 May;28(5):588-94. doi: 10.1016/s0046-8177(97)90081-2. PMID: 9158707
From the archives of the AFIP. Extraskeletal osseous and cartilaginous tumors of the extremities.
Kransdorf MJ, Meis JM
Radiographics 1993 Jul;13(4):853-84. doi: 10.1148/radiographics.13.4.8356273. PMID: 8356273

Supplemental Content

Table of contents

    Practice guidelines

    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...