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del(14q21)

MedGen UID:
271840
•Concept ID:
C1515585
•
Cell or Molecular Dysfunction
Synonym: del(14)(q21)

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVdel(14q21)

Recent clinical studies

Etiology

Chromosome aberrations in a series of 120 multiple myeloma cases with abnormal karyotypes.
Mohamed AN, Bentley G, Bonnett ML, Zonder J, Al-Katib A
Am J Hematol 2007 Dec;82(12):1080-7. doi: 10.1002/ajh.20998. PMID: 17654686
Identification of cytogenetic subclasses and recurring chromosomal aberrations in AML and MDS with complex karyotypes using M-FISH.
Van Limbergen H, Poppe B, Michaux L, Herens C, Brown J, Noens L, Berneman Z, De Bock R, De Paepe A, Speleman F
Genes Chromosomes Cancer 2002 Jan;33(1):60-72. doi: 10.1002/gcc.1212. PMID: 11746988

Therapy

Two chromosome aberrations in the child of a woman with systemic lupus erythematosus treated with azathioprine and prednisone.
Ostrer H, Stamberg J, Perinchief P
Am J Med Genet 1984 Mar;17(3):627-32. doi: 10.1002/ajmg.1320170312. PMID: 6711614

Prognosis

Chromosome aberrations in a series of 120 multiple myeloma cases with abnormal karyotypes.
Mohamed AN, Bentley G, Bonnett ML, Zonder J, Al-Katib A
Am J Hematol 2007 Dec;82(12):1080-7. doi: 10.1002/ajh.20998. PMID: 17654686
Identification of cytogenetic subclasses and recurring chromosomal aberrations in AML and MDS with complex karyotypes using M-FISH.
Van Limbergen H, Poppe B, Michaux L, Herens C, Brown J, Noens L, Berneman Z, De Bock R, De Paepe A, Speleman F
Genes Chromosomes Cancer 2002 Jan;33(1):60-72. doi: 10.1002/gcc.1212. PMID: 11746988

Clinical prediction guides

Chromosome aberrations in a series of 120 multiple myeloma cases with abnormal karyotypes.
Mohamed AN, Bentley G, Bonnett ML, Zonder J, Al-Katib A
Am J Hematol 2007 Dec;82(12):1080-7. doi: 10.1002/ajh.20998. PMID: 17654686
Cumulative dosage effect of a RAD51L1/HMGA2 fusion and RAD51L1 loss in a case of pseudo-Meigs' syndrome.
Amant F, Debiec-Rychter M, Schoenmakers EF, Hagemeijer-Hausman A, Vergote I
Genes Chromosomes Cancer 2001 Dec;32(4):324-9. doi: 10.1002/gcc.1197. PMID: 11746973

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