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Potassium deficiency disease

MedGen UID:
271346
Concept ID:
C1514284
Disease or Syndrome
Synonyms: hypokalemia; hypopotassemia; potassium deficiency disease; Potassium Deficiency Disorder; potassium deficiency disorder
 
Monarch Initiative: MONDO:0003019

Definition

Any disorder caused by an insufficient amount or availability of potassium, which generally manifests with myalgia, tetany, hypotension, polyuria, and polydipsia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPotassium deficiency disease

Professional guidelines

PubMed

Kim H, Rebholz CM
Curr Opin Nephrol Hypertens 2024 Nov 1;33(6):593-602. Epub 2024 Aug 6 doi: 10.1097/MNH.0000000000001015. PMID: 39115418Free PMC Article
Do C, Vasquez PC, Soleimani M
Am J Kidney Dis 2022 Oct;80(4):536-551. Epub 2022 May 5 doi: 10.1053/j.ajkd.2021.12.016. PMID: 35525634Free PMC Article
Palmer BF, Kelepouris E, Clegg DJ
Adv Ther 2021 Feb;38(2):949-968. Epub 2020 Dec 26 doi: 10.1007/s12325-020-01587-5. PMID: 33367987Free PMC Article

Recent clinical studies

Etiology

Jomova K, Makova M, Alomar SY, Alwasel SH, Nepovimova E, Kuca K, Rhodes CJ, Valko M
Chem Biol Interact 2022 Nov 1;367:110173. Epub 2022 Sep 22 doi: 10.1016/j.cbi.2022.110173. PMID: 36152810
Hu M, Li P, Wang C, Feng X, Geng Q, Chen W, Marthi M, Zhang W, Gao C, Reid W, Swanson J, Du W, Hume RI, Xu H
Cell 2022 Jun 23;185(13):2292-2308.e20. doi: 10.1016/j.cell.2022.05.021. PMID: 35750034Free PMC Article
Tangvoraphonkchai K, Davenport A
Adv Chronic Kidney Dis 2018 May;25(3):251-260. doi: 10.1053/j.ackd.2018.02.010. PMID: 29793664
Stone MS, Martyn L, Weaver CM
Nutrients 2016 Jul 22;8(7) doi: 10.3390/nu8070444. PMID: 27455317Free PMC Article
Craig WJ
Am J Clin Nutr 2009 May;89(5):1627S-1633S. Epub 2009 Mar 11 doi: 10.3945/ajcn.2009.26736N. PMID: 19279075

Diagnosis

Wang SSY, Tang H, Ho WQJ, Asif S, Li YX, Ekladious A, Javaid MM
Br J Hosp Med (Lond) 2024 Oct 30;85(10):1-12. Epub 2024 Oct 14 doi: 10.12968/hmed.2024.0290. PMID: 39475030
Pérez-Dueñas B, Gorman K, Marcé-Grau A, Ortigoza-Escobar JD, Macaya A, Danti FR, Barwick K, Papandreou A, Ng J, Meyer E, Mohammad SS, Smith M, Muntoni F, Munot P, Uusimaa J, Vieira P, Sheridan E, Guerrini R, Cobben J, Yilmaz S, De Grandis E, Dale RC, Pons R, Peall KJ, Leuzzi V, Kurian MA
Mov Disord 2022 Nov;37(11):2197-2209. Epub 2022 Aug 25 doi: 10.1002/mds.29182. PMID: 36054588Free PMC Article
Do C, Vasquez PC, Soleimani M
Am J Kidney Dis 2022 Oct;80(4):536-551. Epub 2022 May 5 doi: 10.1053/j.ajkd.2021.12.016. PMID: 35525634Free PMC Article
Palmer BF, Kelepouris E, Clegg DJ
Adv Ther 2021 Feb;38(2):949-968. Epub 2020 Dec 26 doi: 10.1007/s12325-020-01587-5. PMID: 33367987Free PMC Article
Szczuko M, Skowronek M, Zapałowska-Chwyć M, Starczewski A
Rocz Panstw Zakl Hig 2016;67(4):419-426. PMID: 27925712

Therapy

Do C, Vasquez PC, Soleimani M
Am J Kidney Dis 2022 Oct;80(4):536-551. Epub 2022 May 5 doi: 10.1053/j.ajkd.2021.12.016. PMID: 35525634Free PMC Article
Anderson KJ, Cormier RT, Scott PM
World J Gastroenterol 2019 Oct 14;25(38):5732-5772. doi: 10.3748/wjg.v25.i38.5732. PMID: 31636470Free PMC Article
Tangvoraphonkchai K, Davenport A
Adv Chronic Kidney Dis 2018 May;25(3):251-260. doi: 10.1053/j.ackd.2018.02.010. PMID: 29793664
Stone MS, Martyn L, Weaver CM
Nutrients 2016 Jul 22;8(7) doi: 10.3390/nu8070444. PMID: 27455317Free PMC Article
de Baaij JH, Hoenderop JG, Bindels RJ
Physiol Rev 2015 Jan;95(1):1-46. doi: 10.1152/physrev.00012.2014. PMID: 25540137

Prognosis

Baez G, Chirio M, Pisula P, Seminario E, Carasa N, Philippi R, Aroca-Martinez G, Musso CG
Ir J Med Sci 2024 Apr;193(2):1043-1046. Epub 2023 Sep 13 doi: 10.1007/s11845-023-03490-8. PMID: 37702978Free PMC Article
Anderson KJ, Cormier RT, Scott PM
World J Gastroenterol 2019 Oct 14;25(38):5732-5772. doi: 10.3748/wjg.v25.i38.5732. PMID: 31636470Free PMC Article
Asmus F, Gasser T
Eur J Neurol 2010 Jul;17 Suppl 1:37-45. doi: 10.1111/j.1468-1331.2010.03049.x. PMID: 20590807
Piga M, Serra A, Boi F, Tanda ML, Martino E, Mariotti S
Minerva Endocrinol 2008 Sep;33(3):213-28. PMID: 18846027
Loi M
Orphanet J Rare Dis 2006 May 18;1:16. doi: 10.1186/1750-1172-1-16. PMID: 16722554Free PMC Article

Clinical prediction guides

Pérez-Dueñas B, Gorman K, Marcé-Grau A, Ortigoza-Escobar JD, Macaya A, Danti FR, Barwick K, Papandreou A, Ng J, Meyer E, Mohammad SS, Smith M, Muntoni F, Munot P, Uusimaa J, Vieira P, Sheridan E, Guerrini R, Cobben J, Yilmaz S, De Grandis E, Dale RC, Pons R, Peall KJ, Leuzzi V, Kurian MA
Mov Disord 2022 Nov;37(11):2197-2209. Epub 2022 Aug 25 doi: 10.1002/mds.29182. PMID: 36054588Free PMC Article
Palmer BF, Kelepouris E, Clegg DJ
Adv Ther 2021 Feb;38(2):949-968. Epub 2020 Dec 26 doi: 10.1007/s12325-020-01587-5. PMID: 33367987Free PMC Article
Tangvoraphonkchai K, Davenport A
Adv Chronic Kidney Dis 2018 May;25(3):251-260. doi: 10.1053/j.ackd.2018.02.010. PMID: 29793664
Korzh V
Cell Mol Life Sci 2018 Feb;75(3):375-383. Epub 2017 Aug 5 doi: 10.1007/s00018-017-2605-y. PMID: 28780589Free PMC Article
Blaszczyk U, Duda-Chodak A
Rocz Panstw Zakl Hig 2013;64(3):165-71. PMID: 24325082

Recent systematic reviews

Ehrenpreis ED, Jarrouj G, Meader R, Wagner C, Ellis M
Dis Mon 2022 Feb;68(2):101285. Epub 2021 Sep 10 doi: 10.1016/j.disamonth.2021.101285. PMID: 34511254
Rucker D, Thadhani R, Tonelli M
Semin Dial 2010 Jul-Aug;23(4):389-95. Epub 2010 Jun 14 doi: 10.1111/j.1525-139X.2010.00746.x. PMID: 20557491
Wu T, Liu GJ, Li P, Clar C
Cochrane Database Syst Rev 2002;2002(3):CD003204. doi: 10.1002/14651858.CD003204. PMID: 12137681Free PMC Article

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