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Infiltrating bladder urothelial carcinoma, clear cell variant

MedGen UID:
268572
•Concept ID:
C1512737
•
Neoplastic Process
Synonyms: Bladder Clear Cell (Glycogen-Rich) Urothelial Carcinoma; Bladder Clear Cell Urothelial Carcinoma; clear cell variant infiltrating bladder urothelial carcinoma; Infiltrating Bladder Urothelial Carcinoma, Clear Cell Variant; infiltrating bladder urothelial carcinoma, clear cell variant; Invasive Bladder Clear Cell (Glycogen-Rich) Urothelial Carcinoma; Invasive Bladder Urothelial Carcinoma, Clear Cell (Glycogen-Rich) Variant; Invasive Bladder Urothelial Carcinoma, Clear Cell Variant
 
Monarch Initiative: MONDO:0003889

Definition

An invasive urothelial carcinoma of the bladder characterized by the presence of clear (glycogen-rich) cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInfiltrating bladder urothelial carcinoma, clear cell variant

Recent clinical studies

Etiology

Clear Cell carcinoma of the urinary bladder, A case report: Surgical and oncological management.
Corongiu E, Grande P, Liberati E, Iacovelli R, Amini M, Mascioli P, Pagliarella G, Squillacciotti S, Di Santo A, Zampelli A, Forte F, Olivieri V
Arch Ital Urol Androl 2020 Oct 2;92(3) doi: 10.4081/aiua.2020.3.218. PMID: 33016051

Diagnosis

Nephrogenic Adenoma Intermixed With Urothelial Carcinoma.
Kryvenko ON, Wasco MJ, Williamson SR
Arch Pathol Lab Med 2022 May 1;147(5):552-558. doi: 10.5858/arpa.2021-0620-OA. PMID: 35976666
Primary clear-cell urothelial carcinoma of urinary bladder: a not-so-clear entity with review of literature.
Kumar L, Narwal A, Kumar M, Kaushal S
BMJ Case Rep 2019 Oct 23;12(10) doi: 10.1136/bcr-2019-231192. PMID: 31645400Free PMC Article
Lipoid-cell variant of urothelial carcinoma: report of a new case of the urinary bladder.
De Giorgi G, Pizzolitto S, Sacco C, Kocjancic E, Frea B, Falconieri G
Arch Ital Urol Androl 2007 Dec;79(4):173-5. PMID: 18303737
Lipoid-cell variant of urothelial carcinoma: a clinicopathologic and immunohistochemical study of five cases.
Leroy X, Gonzalez S, Zini L, Aubert S
Am J Surg Pathol 2007 May;31(5):770-3. doi: 10.1097/01.pas.0000213410.48805.16. PMID: 17460462
High-grade urothelial carcinoma of the renal pelvis: clinicopathologic study of 108 cases with emphasis on unusual morphologic variants.
Perez-Montiel D, Wakely PE, Hes O, Michal M, Suster S
Mod Pathol 2006 Apr;19(4):494-503. doi: 10.1038/modpathol.3800559. PMID: 16474378

Therapy

Clear Cell carcinoma of the urinary bladder, A case report: Surgical and oncological management.
Corongiu E, Grande P, Liberati E, Iacovelli R, Amini M, Mascioli P, Pagliarella G, Squillacciotti S, Di Santo A, Zampelli A, Forte F, Olivieri V
Arch Ital Urol Androl 2020 Oct 2;92(3) doi: 10.4081/aiua.2020.3.218. PMID: 33016051

Prognosis

Clear Cell carcinoma of the urinary bladder, A case report: Surgical and oncological management.
Corongiu E, Grande P, Liberati E, Iacovelli R, Amini M, Mascioli P, Pagliarella G, Squillacciotti S, Di Santo A, Zampelli A, Forte F, Olivieri V
Arch Ital Urol Androl 2020 Oct 2;92(3) doi: 10.4081/aiua.2020.3.218. PMID: 33016051
Primary clear-cell urothelial carcinoma of urinary bladder: a not-so-clear entity with review of literature.
Kumar L, Narwal A, Kumar M, Kaushal S
BMJ Case Rep 2019 Oct 23;12(10) doi: 10.1136/bcr-2019-231192. PMID: 31645400Free PMC Article
Lipoid-cell variant of urothelial carcinoma: a clinicopathologic and immunohistochemical study of five cases.
Leroy X, Gonzalez S, Zini L, Aubert S
Am J Surg Pathol 2007 May;31(5):770-3. doi: 10.1097/01.pas.0000213410.48805.16. PMID: 17460462

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