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Bladder squamous papilloma

MedGen UID:
267742
•Concept ID:
C1511199
•
Neoplastic Process
Synonyms: Bladder Keratotic Papilloma; Bladder Squamous Cell Papilloma; Bladder Squamous Papilloma; bladder squamous papilloma
 
Monarch Initiative: MONDO:0001635

Definition

A rare, benign neoplasm of bladder that is composed of papillary cores with overlying histologically benign squamous epithelium. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBladder squamous papilloma

Professional guidelines

PubMed

The Genitourinary Pathology Society Update on Classification and Grading of Flat and Papillary Urothelial Neoplasia With New Reporting Recommendations and Approach to Lesions With Mixed and Early Patterns of Neoplasia.
Amin MB, Comperat E, Epstein JI, True LD, Hansel D, Paner GP, Al-Ahmadie H, Baydar D, Bivalacqua T, Brimo F, Cheng L, Cheville J, Dalbagni G, Falzarano S, Gordetsky J, Guo CC, Gupta S, Hes O, Iyer G, Kaushal S, Kunju L, Magi-Galluzzi C, Matoso A, Netto G, Osunkoya AO, Pan CC, Pivovarcikova K, Raspollini MR, Reis H, Rosenberg J, Roupret M, Shah RB, Shariat S, Trpkov K, Weyerer V, Zhou M, McKenney J, Reuter VE
Adv Anat Pathol 2021 Jul 1;28(4):179-195. doi: 10.1097/PAP.0000000000000308. PMID: 34128483
Evaluation and management of vaginoplasty complications.
Amies Oelschlager AM, Kirby A, Breech L
Curr Opin Obstet Gynecol 2017 Oct;29(5):316-321. doi: 10.1097/GCO.0000000000000391. PMID: 28696998
Histologic variants of urothelial carcinoma: differential diagnosis and clinical implications.
Lopez-Beltran A, Cheng L
Hum Pathol 2006 Nov;37(11):1371-88. Epub 2006 Jul 31 doi: 10.1016/j.humpath.2006.05.009. PMID: 16949919

Recent clinical studies

Etiology

Squamous Cell Carcinoma of the Bladder Is Not Associated With High-risk HPV.
Gordetsky J, Spieker AJ, Pena MDCR, Kamanda S, Anderson MR, Cheville J, Boorjian S, Frank I, Granada CP, Comperat E, Hirsch MS, Iczkowski KA, Imblum B, Schwartz L, Giannico GA, Rais-Bahrami S
Urology 2020 Oct;144:158-163. Epub 2020 Jul 16 doi: 10.1016/j.urology.2020.06.065. PMID: 32681917
Evaluation and management of vaginoplasty complications.
Amies Oelschlager AM, Kirby A, Breech L
Curr Opin Obstet Gynecol 2017 Oct;29(5):316-321. doi: 10.1097/GCO.0000000000000391. PMID: 28696998
Inverted papilloma of the bladder: a review and an analysis of the recent literature of 365 patients.
Picozzi S, Casellato S, Bozzini G, Ratti D, Macchi A, Rubino B, Pace G, Carmignani L
Urol Oncol 2013 Nov;31(8):1584-90. Epub 2012 Apr 19 doi: 10.1016/j.urolonc.2012.03.009. PMID: 22520573
Bladder cancer: clinical and pathological profile.
Lopez-Beltran A
Scand J Urol Nephrol Suppl 2008 Sep;(218):95-109. doi: 10.1080/03008880802325226. PMID: 18815924
Urinary bladder carcinogenesis.
Cohen SM
Toxicol Pathol 1998 Jan-Feb;26(1):121-7. doi: 10.1177/019262339802600114. PMID: 9502394

Diagnosis

Squamous Cell Carcinoma of the Bladder Is Not Associated With High-risk HPV.
Gordetsky J, Spieker AJ, Pena MDCR, Kamanda S, Anderson MR, Cheville J, Boorjian S, Frank I, Granada CP, Comperat E, Hirsch MS, Iczkowski KA, Imblum B, Schwartz L, Giannico GA, Rais-Bahrami S
Urology 2020 Oct;144:158-163. Epub 2020 Jul 16 doi: 10.1016/j.urology.2020.06.065. PMID: 32681917
Mimickers of urothelial neoplasia.
Kryvenko ON, Epstein JI
Ann Diagn Pathol 2019 Feb;38:11-19. Epub 2018 Sep 26 doi: 10.1016/j.anndiagpath.2018.09.012. PMID: 30380401
Mammary and extramammary Paget's disease.
Lopes Filho LL, Lopes IM, Lopes LR, Enokihara MM, Michalany AO, Matsunaga N
An Bras Dermatol 2015 Mar-Apr;90(2):225-31. doi: 10.1590/abd1806-4841.20153189. PMID: 25830993Free PMC Article
Premalignant lesions of the urinary bladder.
Samaratunga H, Martignoni G, Egevad L, Delahunt B
Pathology 2013 Apr;45(3):243-50. doi: 10.1097/PAT.0b013e32835f6169. PMID: 23448810
Morphological diagnosis of urothelial neoplasms.
Montironi R, Mazzucchelli R, Scarpelli M, Lopez-Beltran A, Cheng L
J Clin Pathol 2008 Jan;61(1):3-10. Epub 2007 Jun 1 doi: 10.1136/jcp.2007.049312. PMID: 17545560

Therapy

Urothelial carcinoma in children: A case series.
Marinoni F, Destro F, Selvaggio GGO, Riccipetitoni G
Bull Cancer 2018 Jun;105(6):556-561. Epub 2018 May 1 doi: 10.1016/j.bulcan.2018.03.002. PMID: 29724585
Evaluation and management of vaginoplasty complications.
Amies Oelschlager AM, Kirby A, Breech L
Curr Opin Obstet Gynecol 2017 Oct;29(5):316-321. doi: 10.1097/GCO.0000000000000391. PMID: 28696998
Superficial bladder cancer: part 1. Update on etiology, classification and natural history.
Josephson DY, Pasin E, Stein JP
Expert Rev Anticancer Ther 2006 Dec;6(12):1723-34. doi: 10.1586/14737140.6.12.1723. PMID: 17181486
Bladder cancer in women.
van der Poel HG, Mungan NA, Witjes JA
Int Urogynecol J Pelvic Floor Dysfunct 1999;10(3):207-12. doi: 10.1007/s001920050046. PMID: 10430016
Urinary bladder carcinogenesis.
Cohen SM
Toxicol Pathol 1998 Jan-Feb;26(1):121-7. doi: 10.1177/019262339802600114. PMID: 9502394

Prognosis

Proteogenomics of different urothelial bladder cancer stages reveals distinct molecular features for papillary cancer and carcinoma in situ.
Yao Z, Xu N, Shang G, Wang H, Tao H, Wang Y, Qin Z, Tan S, Feng J, Zhu J, Ma F, Tian S, Zhang Q, Qu Y, Hou J, Guo J, Zhao J, Hou Y, Ding C
Nat Commun 2023 Sep 13;14(1):5670. doi: 10.1038/s41467-023-41139-3. PMID: 37704624Free PMC Article
Squamous Cell Carcinoma of the Bladder Is Not Associated With High-risk HPV.
Gordetsky J, Spieker AJ, Pena MDCR, Kamanda S, Anderson MR, Cheville J, Boorjian S, Frank I, Granada CP, Comperat E, Hirsch MS, Iczkowski KA, Imblum B, Schwartz L, Giannico GA, Rais-Bahrami S
Urology 2020 Oct;144:158-163. Epub 2020 Jul 16 doi: 10.1016/j.urology.2020.06.065. PMID: 32681917
Mammary and extramammary Paget's disease.
Lopes Filho LL, Lopes IM, Lopes LR, Enokihara MM, Michalany AO, Matsunaga N
An Bras Dermatol 2015 Mar-Apr;90(2):225-31. doi: 10.1590/abd1806-4841.20153189. PMID: 25830993Free PMC Article
Inverted papilloma of the bladder: a review and an analysis of the recent literature of 365 patients.
Picozzi S, Casellato S, Bozzini G, Ratti D, Macchi A, Rubino B, Pace G, Carmignani L
Urol Oncol 2013 Nov;31(8):1584-90. Epub 2012 Apr 19 doi: 10.1016/j.urolonc.2012.03.009. PMID: 22520573
Bladder cancer in women.
van der Poel HG, Mungan NA, Witjes JA
Int Urogynecol J Pelvic Floor Dysfunct 1999;10(3):207-12. doi: 10.1007/s001920050046. PMID: 10430016

Clinical prediction guides

Quantitative differentiation of non-invasive bladder urothelial carcinoma and inverted papilloma based on CT urography.
Jin P, Yang L, Liu Y, Huang J, Wang X
BMC Urol 2024 Mar 26;24(1):73. doi: 10.1186/s12894-024-01459-y. PMID: 38532363Free PMC Article
HPV-positive clinically advanced squamous cell carcinoma of the urinary bladder (aBSCC): A comprehensive genomic profiling (CGP) study.
Ghelani GH, Zerdan MB, Jacob J, Spiess PE, Li R, Necchi A, Grivas P, Kamat A, Danziger N, Lin D, Huang R, Decker B, Sokol ES, Cheng L, Pavlick D, Ross JS, Bratslavsky G, Basnet A
Urol Oncol 2023 Dec;41(12):486.e15-486.e23. Epub 2023 Oct 9 doi: 10.1016/j.urolonc.2023.09.001. PMID: 37821306
Squamous Cell Carcinoma of the Bladder Is Not Associated With High-risk HPV.
Gordetsky J, Spieker AJ, Pena MDCR, Kamanda S, Anderson MR, Cheville J, Boorjian S, Frank I, Granada CP, Comperat E, Hirsch MS, Iczkowski KA, Imblum B, Schwartz L, Giannico GA, Rais-Bahrami S
Urology 2020 Oct;144:158-163. Epub 2020 Jul 16 doi: 10.1016/j.urology.2020.06.065. PMID: 32681917
Urinary bladder carcinogenesis.
Cohen SM
Toxicol Pathol 1998 Jan-Feb;26(1):121-7. doi: 10.1177/019262339802600114. PMID: 9502394
Urothelial neoplasia.
Murphy WM
Monogr Pathol 1992;(34):77-111. PMID: 1406745

Recent systematic reviews

Inverted papilloma of the bladder: a review and an analysis of the recent literature of 365 patients.
Picozzi S, Casellato S, Bozzini G, Ratti D, Macchi A, Rubino B, Pace G, Carmignani L
Urol Oncol 2013 Nov;31(8):1584-90. Epub 2012 Apr 19 doi: 10.1016/j.urolonc.2012.03.009. PMID: 22520573

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