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Cutaneous candidiasis

MedGen UID:
2427
•Concept ID:
C0006846
•
Disease or Syndrome
Synonyms: Candidiasis, Cutaneous; Moniliasis, Cutaneous
SNOMED CT: Candidosis of skin (49883006); Candida of skin (49883006); Candidiasis of skin (49883006)
 
Monarch Initiative: MONDO:0000879

Definition

Candidiasis of the skin manifested as eczema-like lesions of the interdigital spaces, perleche, or chronic paronychia. (Dorland, 27th ed) [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCutaneous candidiasis

Professional guidelines

PubMed

The diagnosis, management and prevention of intertrigo in adults: a review.
Romanelli M, Voegeli D, Colboc H, Bassetto F, Janowska A, Scarpa C, Meaume S
J Wound Care 2023 Jul 2;32(7):411-420. doi: 10.12968/jowc.2023.32.7.411. PMID: 37405940
Mycological Considerations in the Topical Treatment of Superficial Fungal Infections.
Rosen T
J Drugs Dermatol 2016 Feb;15(2 Suppl):s49-55. PMID: 26885799
Ciclopirox for the treatment of superficial fungal infections: a review.
Gupta AK, Skinner AR
Int J Dermatol 2003 Sep;42 Suppl 1:3-9. doi: 10.1046/j.1365-4362.42.s1.2.x. PMID: 12895181

Recent clinical studies

Etiology

Cutaneous candidiasis - an evidence-based review of topical and systemic treatments to inform clinical practice.
Taudorf EH, Jemec GBE, Hay RJ, Saunte DML
J Eur Acad Dermatol Venereol 2019 Oct;33(10):1863-1873. Epub 2019 Jul 30 doi: 10.1111/jdv.15782. PMID: 31287594
Angioinvasive fungal infections impacting the skin: Background, epidemiology, and clinical presentation.
Shields BE, Rosenbach M, Brown-Joel Z, Berger AP, Ford BA, Wanat KA
J Am Acad Dermatol 2019 Apr;80(4):869-880.e5. Epub 2018 Aug 10 doi: 10.1016/j.jaad.2018.04.059. PMID: 30102951
Erosio interdigitalis blastomycetica: A review of interdigital candidiasis.
Schlager E, Ashack K, Khachemoune A
Dermatol Online J 2018 Aug 15;24(8) PMID: 30677843
Incontinence-associated dermatitis: a comprehensive review and update.
Gray M, Beeckman D, Bliss DZ, Fader M, Logan S, Junkin J, Selekof J, Doughty D, Kurz P
J Wound Ostomy Continence Nurs 2012 Jan-Feb;39(1):61-74. doi: 10.1097/WON.0b013e31823fe246. PMID: 22193141
Cutaneous mycoses in children.
Elewski BE
Br J Dermatol 1996 Jun;134 Suppl 46:7-11: discussion 37-8. doi: 10.1111/j.1365-2133.1996.tb15651.x. PMID: 8763460

Diagnosis

The diagnosis, management and prevention of intertrigo in adults: a review.
Romanelli M, Voegeli D, Colboc H, Bassetto F, Janowska A, Scarpa C, Meaume S
J Wound Care 2023 Jul 2;32(7):411-420. doi: 10.12968/jowc.2023.32.7.411. PMID: 37405940
Infections in the monogenic autoimmune syndrome APECED.
Oikonomou V, Break TJ, Gaffen SL, Moutsopoulos NM, Lionakis MS
Curr Opin Immunol 2021 Oct;72:286-297. Epub 2021 Aug 18 doi: 10.1016/j.coi.2021.07.011. PMID: 34418591Free PMC Article
British Association of Dermatologists' guidelines for the management of onychomycosis 2014.
Ameen M, Lear JT, Madan V, Mohd Mustapa MF, Richardson M
Br J Dermatol 2014 Nov;171(5):937-58. doi: 10.1111/bjd.13358. PMID: 25409999
The wisdom of pain.
Lawrence RA
Breastfeed Med 2014 Mar;9(2):51-2. doi: 10.1089/bfm.2014.9993. PMID: 24564562
Cutaneous mycoses in children.
Elewski BE
Br J Dermatol 1996 Jun;134 Suppl 46:7-11: discussion 37-8. doi: 10.1111/j.1365-2133.1996.tb15651.x. PMID: 8763460

Therapy

Candidiasis: From cutaneous to systemic, new perspectives of potential targets and therapeutic strategies.
Lu H, Hong T, Jiang Y, Whiteway M, Zhang S
Adv Drug Deliv Rev 2023 Aug;199:114960. Epub 2023 Jun 10 doi: 10.1016/j.addr.2023.114960. PMID: 37307922
Cutaneous candidiasis - an evidence-based review of topical and systemic treatments to inform clinical practice.
Taudorf EH, Jemec GBE, Hay RJ, Saunte DML
J Eur Acad Dermatol Venereol 2019 Oct;33(10):1863-1873. Epub 2019 Jul 30 doi: 10.1111/jdv.15782. PMID: 31287594
The wisdom of pain.
Lawrence RA
Breastfeed Med 2014 Mar;9(2):51-2. doi: 10.1089/bfm.2014.9993. PMID: 24564562
Naftifine: a review.
Gupta AK, Ryder JE, Cooper EA
J Cutan Med Surg 2008 Mar-Apr;12(2):51-8. doi: 10.2310/7750.2008.06009. PMID: 18346400
Diaper dermatitis--an overview.
Prasad HR, Srivastava P, Verma KK
Indian J Pediatr 2003 Aug;70(8):635-7. doi: 10.1007/BF02724253. PMID: 14510084

Prognosis

Isolated Cutaneous Granuloma Caused by Candida glabrata: A Rare Case Report and Literature Review.
Fan Y, Pan W, Wang G, Huang Y, Li Y, Fang W, Tao X
Mycopathologia 2018 Apr;183(2):417-421. Epub 2017 Nov 22 doi: 10.1007/s11046-017-0228-3. PMID: 29164434
Nail disease in pemphigus vulgaris.
Serratos BD, Rashid RM
Dermatol Online J 2009 Jul 15;15(7):2. PMID: 19903430
Diaper dermatitis: a review and brief survey of eruptions of the diaper area.
Scheinfeld N
Am J Clin Dermatol 2005;6(5):273-81. doi: 10.2165/00128071-200506050-00001. PMID: 16252927
Fungal skin disorders.
Rupke SJ
Prim Care 2000 Jun;27(2):407-21. doi: 10.1016/s0095-4543(05)70203-7. PMID: 10815051
Dermatologic complications in colostomy and ileostomy patients.
Hellman J, Lago CP
Int J Dermatol 1990 Mar;29(2):129-33. doi: 10.1111/j.1365-4362.1990.tb04085.x. PMID: 2182551

Clinical prediction guides

Congenital candidiasis in a full-term infant: A case report.
Zhao HH, Zhe-Zhou, Lu L, Zhao YZ, Yang LJ, Ding YX
J Int Med Res 2023 Apr;51(4):3000605231158015. doi: 10.1177/03000605231158015. PMID: 37062969Free PMC Article
Nipple pain, damage, and vasospasm in the first 8 weeks postpartum.
Buck ML, Amir LH, Cullinane M, Donath SM; CASTLE Study Team
Breastfeed Med 2014 Mar;9(2):56-62. Epub 2013 Dec 31 doi: 10.1089/bfm.2013.0106. PMID: 24380583Free PMC Article
Skin interaction with absorbent hygiene products.
Runeman B
Clin Dermatol 2008 Jan-Feb;26(1):45-51. doi: 10.1016/j.clindermatol.2007.10.002. PMID: 18280904
Clinical and mycological spectrum of cutaneous candidiasis in Bombay.
Shroff PS, Parikh DA, Fernandez RJ, Wagle UD
J Postgrad Med 1990 Apr;36(2):83-6. PMID: 2097373
Mycoses in India--study in Madras.
Kamalam A, Thambiah AS, Bagavandas M, Govindaraju S
Trans R Soc Trop Med Hyg 1981;75(1):92-100. doi: 10.1016/0035-9203(81)90017-1. PMID: 7268862

Recent systematic reviews

Vulvovaginal candidiasis in Iran: A systematic review and meta-analysis on the epidemiology, clinical manifestations, demographic characteristics, risk factors, etiologic agents and laboratory diagnosis.
Sasani E, Rafat Z, Ashrafi K, Salimi Y, Zandi M, Soltani S, Hashemi F, Hashemi SJ
Microb Pathog 2021 May;154:104802. Epub 2021 Mar 16 doi: 10.1016/j.micpath.2021.104802. PMID: 33741400
Novel use of terpenoids for treatment of dermatologic diseases: a systematic review of clinical trials.
Tuong W, Walker L, Sivamani RK
J Altern Complement Med 2015 May;21(5):261-8. Epub 2015 Apr 29 doi: 10.1089/acm.2014.0273. PMID: 25923990
Efficacy of topical antifungal drugs in different dermatomycoses: a systematic review with meta-analysis.
Rotta I, Otuki MF, Sanches AC, Correr CJ
Rev Assoc Med Bras (1992) 2012 May-Jun;58(3):308-18. PMID: 22735222

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