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Vaginal Obstruction

MedGen UID:
235615
•Concept ID:
C1408443
•
Pathologic Function

Definition

Congenital or acquired blockage of the vagina. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVaginal Obstruction

Professional guidelines

PubMed

Incorporation of whole pelvic radiation into treatment of stage IVB cervical cancer: A novel treatment strategy.
Perkins V, Moore K, Vesely S, Matsuo K, Mostofizadeh S, Sims TT, Lea J, Barnes D, Chen S, Carlson M, Roman L, Monk BJ, Holman LL
Gynecol Oncol 2020 Jan;156(1):100-106. Epub 2019 Dec 4 doi: 10.1016/j.ygyno.2019.10.033. PMID: 31810653Free PMC Article
The management of severe vaginal obstruction from genital chronic graft-versus-host disease: diagnosis, surgical technique and follow-up.
Costantini S, Di Capua E, Bosi S, Chiodi S, Spinelli S
Minerva Ginecol 2006 Feb;58(1):11-6. PMID: 16498366

Recent clinical studies

Etiology

Herlyn-Werner-Wunderlich syndrome: diverse presentations and diagnosis on MRI.
Zhang H, Ning G, Fu C, Bao L, Guo Y
Clin Radiol 2020 Jun;75(6):480.e17-480.e25. Epub 2020 Mar 11 doi: 10.1016/j.crad.2020.01.016. PMID: 32171579
Hematoureter due to endometriosis.
Lakhi N, Dun EC, Nezhat CH
Fertil Steril 2014 Jun;101(6):e37. Epub 2014 Mar 26 doi: 10.1016/j.fertnstert.2014.02.049. PMID: 24680366
Prepubertal presentation of Herlyn-Werner-Wunderlich syndrome: a case report.
Sanghvi Y, Shastri P, Mane SB, Dhende NP
J Pediatr Surg 2011 Jun;46(6):1277-80. doi: 10.1016/j.jpedsurg.2011.02.067. PMID: 21683238
Congenital vaginal obstruction in neonates and infants: recognition and management.
Ameh EA, Mshelbwala PM, Ameh N
J Pediatr Adolesc Gynecol 2011 Apr;24(2):74-8. Epub 2011 Jan 22 doi: 10.1016/j.jpag.2010.08.016. PMID: 21256779
Presenting and long-term clinical implications and fecundity in females with obstructing vaginal malformations.
Joki-Erkkilä MM, Heinonen PK
J Pediatr Adolesc Gynecol 2003 Oct;16(5):307-12. doi: 10.1016/s1083-3188(03)00157-8. PMID: 14597020

Diagnosis

Obstructed hemivagina with ipsilateral renal and urinary tract anomaly presenting as an unusual cause of acute abdomen: a radiologic perspective.
Mendoza KIR, Nicer DPC
BMJ Case Rep 2022 Jun 27;15(6) doi: 10.1136/bcr-2022-249959. PMID: 35760501Free PMC Article
Vaginal yolk sac tumor causing infantile hydrometra: use of multidetector-row computed tomography.
Wani NA, Robbani I, Andrabi AH, Iqbal A, Qayum A
J Pediatr Adolesc Gynecol 2010 Jun;23(3):e115-8. Epub 2009 Dec 5 doi: 10.1016/j.jpag.2009.10.005. PMID: 19963410
Longitudinal vaginal septum 'obstructive variety'--a challenge for gynaecologist.
Vaid NB, Radhika AG, Radhakrishnan G
J Indian Med Assoc 2008 Apr;106(4):250, 255. PMID: 18828347
Uterus didelphys with unilateral imperforate hemivagina and ipsilateral renal agenesis.
Altintaş A
J Pediatr Adolesc Gynecol 1998 Feb;11(1):25-7. doi: 10.1016/s1083-3188(98)70103-2. PMID: 9526822
The double uterus associated with an obstructed hemivagina and ipsilateral renal agenesis.
Rock JA, Jones HW Jr
Am J Obstet Gynecol 1980 Oct 1;138(3):339-42. doi: 10.1016/0002-9378(80)90260-4. PMID: 7416225

Therapy

Resolution of Hematocolpos in Adolescents Affected with Graft vs Host Disease.
Michala L, Vlachopapadopoulou E, Tsimaris P, Papaioannou G, Paisiou A, Peristeri I, Michalacos S, Kitra V
J Pediatr Adolesc Gynecol 2018 Oct;31(5):536-539. Epub 2018 May 29 doi: 10.1016/j.jpag.2018.05.006. PMID: 29857111
Complete vaginal obstruction with hematometra after hematopoietic stem cell transplantation for chronic myeloid leukemia: a case report.
Rodolakis A, Thomakos N, Harhalakis N, Iconomou T, Antsaklis A
J Reprod Med 2007 Oct;52(10):959-61. PMID: 17977175
The management of severe vaginal obstruction from genital chronic graft-versus-host disease: diagnosis, surgical technique and follow-up.
Costantini S, Di Capua E, Bosi S, Chiodi S, Spinelli S
Minerva Ginecol 2006 Feb;58(1):11-6. PMID: 16498366
Toxic shock syndrome associated with diaphragm use.
Hyde L
J Fam Pract 1983 Mar;16(3):616-7, 620. PMID: 6827238

Prognosis

Evaluation of the abdominopelvic region using MRI in patients with primary amenorrhea.
Gündoğdu E, Emekli E, Oğuzman M, Kebapçı M
J Pediatr Endocrinol Metab 2019 Sep 25;32(9):995-1003. doi: 10.1515/jpem-2019-0223. PMID: 31369396
Prepubertal presentation of Herlyn-Werner-Wunderlich syndrome: a case report.
Sanghvi Y, Shastri P, Mane SB, Dhende NP
J Pediatr Surg 2011 Jun;46(6):1277-80. doi: 10.1016/j.jpedsurg.2011.02.067. PMID: 21683238
The management of severe vaginal obstruction from genital chronic graft-versus-host disease: diagnosis, surgical technique and follow-up.
Costantini S, Di Capua E, Bosi S, Chiodi S, Spinelli S
Minerva Ginecol 2006 Feb;58(1):11-6. PMID: 16498366
The use of isolated caecal bowel segment in complicated vaginal reconstruction.
Filipas D, Black P, Hohenfellner R
BJU Int 2000 Apr;85(6):715-9. doi: 10.1046/j.1464-410x.2000.00482.x. PMID: 10759672
Uterus didelphys with unilateral imperforate hemivagina and ipsilateral renal agenesis.
Altintaş A
J Pediatr Adolesc Gynecol 1998 Feb;11(1):25-7. doi: 10.1016/s1083-3188(98)70103-2. PMID: 9526822

Clinical prediction guides

Cervicovaginal reconstruction with small intestinal submucosa graft in congenital cervicovaginal atresia: A report of 38 cases.
Ding Y, Zhang X, Zhang Y, Shen F, Ding J, Hua K
Eur J Obstet Gynecol Reprod Biol 2021 Dec;267:49-55. Epub 2021 Oct 18 doi: 10.1016/j.ejogrb.2021.10.015. PMID: 34710724
Evaluation of the abdominopelvic region using MRI in patients with primary amenorrhea.
Gündoğdu E, Emekli E, Oğuzman M, Kebapçı M
J Pediatr Endocrinol Metab 2019 Sep 25;32(9):995-1003. doi: 10.1515/jpem-2019-0223. PMID: 31369396
Spasticity of the pelvic floor mimicking an obstructive anomaly.
Quint EH, Smith YR, Bowerman RA, DeLancey JO
J Pediatr Adolesc Gynecol 2003 Apr;16(2):83-5. doi: 10.1016/s1083-3188(03)00010-x. PMID: 12742141
The management of hydrocolpos.
Dell'Agnola CA, Fedele L, Zamberletti D, Fagnani A, Marchini M
Acta Eur Fertil 1984 Jan-Feb;15(1):51-7. PMID: 6730866

Recent systematic reviews

Multiple variants of obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome - one clinical center case series and the systematic review of 734 cases.
Kudela G, Wiernik A, Drosdzol-Cop A, Machnikowska-Sokołowska M, Gawlik A, Hyla-Klekot L, Gruszczyńska K, Koszutski T
J Pediatr Urol 2021 Oct;17(5):653.e1-653.e9. Epub 2021 Jun 30 doi: 10.1016/j.jpurol.2021.06.023. PMID: 34274235

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