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Microcystic meningioma

MedGen UID:: 234616
•Concept ID:: C1384408
•: Neoplastic Process

Synonyms:	Meningioma, Microcystic; Meningiomas, Microcystic; Microcystic Meningioma; Microcystic Meningiomas
SNOMED CT:	Microcystic meningioma (253084001)

Monarch Initiative:	MONDO:0003058

Definition

A WHO grade I meningioma characterized by the presence of intercellular microcystic spaces that contain mucinous fluid. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMicrocystic meningioma

Disorder of nervous system
- Disorder of the central nervous system
  - Neoplasm of the central nervous system
    - Benign neoplasm of the central nervous system
      - Meningioma
        Grade 1 Meningioma
        Microcystic meningioma

Professional guidelines

PubMed

Primary pulmonary meningioma.

Hsu CC, Tsai YM, Yang SF, Hsu JS
Kaohsiung J Med Sci 2023 Nov;39(11):1155-1156. Epub 2023 Sep 12 doi: 10.1002/kjm2.12754. PMID: 37698283

EANO guideline on the diagnosis and management of meningiomas.

Goldbrunner R, Stavrinou P, Jenkinson MD, Sahm F, Mawrin C, Weber DC, Preusser M, Minniti G, Lund-Johansen M, Lefranc F, Houdart E, Sallabanda K, Le Rhun E, Nieuwenhuizen D, Tabatabai G, Soffietti R, Weller M
Neuro Oncol 2021 Nov 2;23(11):1821-1834. doi: 10.1093/neuonc/noab150. PMID: 34181733 Free PMC Article

Management of Spinal Meningiomas.

Ravindra VM, Schmidt MH
Neurosurg Clin N Am 2016 Apr;27(2):195-205. Epub 2016 Feb 18 doi: 10.1016/j.nec.2015.11.010. PMID: 27012384

See all (629)

Recent clinical studies

Etiology

Discrimination between microcystic meningioma and atypical meningioma using whole-lesion apparent diffusion coefficient histogram analysis.

Liu X, Huang X, Han T, Li S, Xue C, Deng J, Zhou Q, Sun Q, Zhou J
Clin Radiol 2022 Nov;77(11):864-869. Epub 2022 Aug 25 doi: 10.1016/j.crad.2022.07.004. PMID: 36030110

Differentiating microcystic meningioma from atypical meningioma using diffusion-weighted imaging.

Xiaoai K, Qing Z, Lei H, Junlin Z
Neuroradiology 2020 May;62(5):601-607. Epub 2020 Jan 29 doi: 10.1007/s00234-020-02374-3. PMID: 31996968

Dual use of E-cadherin and D2-40 immunostaining in unusual meningioma subtypes.

Mrachek EK, Davis D, Kleinschmidt-DeMasters BK
Am J Clin Pathol 2015 Dec;144(6):923-34. doi: 10.1309/AJCPSULJ6DW5REHR. PMID: 26573000

Pediatric microcystic meningioma: a clinical, histological, and radiographic case-based review.

Manwaring J, Ahmadian A, Stapleton S, Gonzalez-Gomez I, Rodriguez L, Carey C, Tuite GF
Childs Nerv Syst 2013 Mar;29(3):361-5. Epub 2012 Dec 19 doi: 10.1007/s00381-012-1991-6. PMID: 23250249

Acute haemorrhage into a microcystic meningioma leading to cerebral herniation.

Sakowitz OW, Harting I, Kohlhof P, Unterberg AW, Steiner HH
Br J Neurosurg 2005 Jun;19(3):260-4. doi: 10.1080/02688690500208734. PMID: 16455530

See all (17)

Diagnosis

Discrimination between microcystic meningioma and atypical meningioma using whole-lesion apparent diffusion coefficient histogram analysis.

Liu X, Huang X, Han T, Li S, Xue C, Deng J, Zhou Q, Sun Q, Zhou J
Clin Radiol 2022 Nov;77(11):864-869. Epub 2022 Aug 25 doi: 10.1016/j.crad.2022.07.004. PMID: 36030110

Intracranial extraosseous dural-based Ewing's sarcoma with fluid-haematocrit levels: imaging findings of a rare tumour.

Mohakud S, Rajasimman AS, Purkait S, Naik S
BMJ Case Rep 2022 Jun 14;15(6) doi: 10.1136/bcr-2021-247056. PMID: 35701017 Free PMC Article

Dual use of E-cadherin and D2-40 immunostaining in unusual meningioma subtypes.

Mrachek EK, Davis D, Kleinschmidt-DeMasters BK
Am J Clin Pathol 2015 Dec;144(6):923-34. doi: 10.1309/AJCPSULJ6DW5REHR. PMID: 26573000

Unique radiological appearance of a microcystic meningioma.

Shimoji K, Yasuma Y, Mori K, Eguchi M, Maeda M
Acta Neurochir (Wien) 1999;141(10):1119-21. doi: 10.1007/s007010050493. PMID: 10550660

Microcystic meningioma of the falx cerebri with numerous palisaded structures: an unusual histological pattern mimicking schwannoma.

Sobel RA, Michaud J
Acta Neuropathol 1985;68(3):256-8. doi: 10.1007/BF00690204. PMID: 4082928

See all (37)

Therapy

Loss of SMARCE1 expression is a specific diagnostic marker of clear cell meningioma: a comprehensive immunophenotypical and molecular analysis.

Tauziede-Espariat A, Parfait B, Besnard A, Lacombe J, Pallud J, Tazi S, Puget S, Lot G, Terris B, Cohen J, Vidaud M, Figarella-Branger D, Monnien F, Polivka M, Adle-Biassette H, Varlet P
Brain Pathol 2018 Jul;28(4):466-474. Epub 2017 Jun 12 doi: 10.1111/bpa.12524. PMID: 28474749 Free PMC Article

Microcystic meningioma: importance of obvious hypointensity on T1-weighted magnetic resonance images.

Chen CJ, Tseng YC, Hsu HL, Jung SM
J Comput Assist Tomogr 2008 Jan-Feb;32(1):130-4. doi: 10.1097/RCT.0b013e318064f127. PMID: 18303301

Microcystic meningioma: clinicopathological features of 6 cases.

Nishio S, Takeshita I, Morioka T, Fukui M
Neurol Res 1994 Aug;16(4):251-6. doi: 10.1080/01616412.1994.11740236. PMID: 7984255

See all (3)

Prognosis

Discrimination between microcystic meningioma and atypical meningioma using whole-lesion apparent diffusion coefficient histogram analysis.

Liu X, Huang X, Han T, Li S, Xue C, Deng J, Zhou Q, Sun Q, Zhou J
Clin Radiol 2022 Nov;77(11):864-869. Epub 2022 Aug 25 doi: 10.1016/j.crad.2022.07.004. PMID: 36030110

Intracranial extraosseous dural-based Ewing's sarcoma with fluid-haematocrit levels: imaging findings of a rare tumour.

Mohakud S, Rajasimman AS, Purkait S, Naik S
BMJ Case Rep 2022 Jun 14;15(6) doi: 10.1136/bcr-2021-247056. PMID: 35701017 Free PMC Article

Differentiating microcystic meningioma from atypical meningioma using diffusion-weighted imaging.

Xiaoai K, Qing Z, Lei H, Junlin Z
Neuroradiology 2020 May;62(5):601-607. Epub 2020 Jan 29 doi: 10.1007/s00234-020-02374-3. PMID: 31996968

Microcystic meningioma arising in a mixed germ cell tumor of the testis: a case report.

Allen EA, Burger PC, Epstein JI
Am J Surg Pathol 1999 Sep;23(9):1131-5. doi: 10.1097/00000478-199909000-00018. PMID: 10478675

Microcystic meningioma. Clinicopathologic report of eight cases.

Michaud J, Gagné F
Arch Pathol Lab Med 1983 Feb;107(2):75-80. PMID: 6687423

See all (19)

Clinical prediction guides

Discrimination between microcystic meningioma and atypical meningioma using whole-lesion apparent diffusion coefficient histogram analysis.

Liu X, Huang X, Han T, Li S, Xue C, Deng J, Zhou Q, Sun Q, Zhou J
Clin Radiol 2022 Nov;77(11):864-869. Epub 2022 Aug 25 doi: 10.1016/j.crad.2022.07.004. PMID: 36030110

Differentiating microcystic meningioma from atypical meningioma using diffusion-weighted imaging.

Xiaoai K, Qing Z, Lei H, Junlin Z
Neuroradiology 2020 May;62(5):601-607. Epub 2020 Jan 29 doi: 10.1007/s00234-020-02374-3. PMID: 31996968

Microcystic meningioma of the calvarium: a series of 9 cases and review of the literature.

Velázquez Vega JE, Rosenberg AE
Am J Surg Pathol 2015 Apr;39(4):505-11. doi: 10.1097/PAS.0000000000000347. PMID: 25517950

Detachment of desmosomes in a microcystic meningioma.

Matsui S, Matsui T, Hirano A
Noshuyo Byori 1995;12(2):85-9. PMID: 8867687

Meningiomas differentiating to arachnoid trabecular cells: a proposal for histological subtype "arachnoid trabecular cell meningioma".

Ito H, Kawano N, Yada K, Kameya T
Acta Neuropathol 1991;82(5):327-30. doi: 10.1007/BF00296542. PMID: 1722606

See all (19)