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Colon Carcinoma Metastatic in the Liver

MedGen UID:
234159
•Concept ID:
C1333085
•
Neoplastic Process
Synonym: Colon Carcinoma Metastatic to the Liver

Definition

A carcinoma that originates from the colonic wall and has spread to the liver. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColon Carcinoma Metastatic in the Liver

Professional guidelines

PubMed

ACR Appropriateness Criteria(®) Pretreatment Staging of Colorectal Cancer.
Expert Panel on Gastrointestinal Imaging:, Fowler KJ, Kaur H, Cash BD, Feig BW, Gage KL, Garcia EM, Hara AK, Herman JM, Kim DH, Lambert DL, Levy AD, Peterson CM, Scheirey CD, Small W Jr, Smith MP, Lalani T, Carucci LR
J Am Coll Radiol 2017 May;14(5S):S234-S244. doi: 10.1016/j.jacr.2017.02.012. PMID: 28473079
The role of capecitabine in the management of tumors of the digestive system.
Gennatas C, Michalaki V, Gennatas S
Rev Recent Clin Trials 2009 Jan;4(1):1-11. doi: 10.2174/157488709787047576. PMID: 19149758
Management of hepatic metastases.
Choti MA, Bulkley GB
Liver Transpl Surg 1999 Jan;5(1):65-80. doi: 10.1002/lt.500050113. PMID: 9873095

Recent clinical studies

Etiology

Role of Liver Biopsy in Assessment of Radiologically Identified Liver Masses.
Khalifa A, Sasso R, Rockey DC
Dig Dis Sci 2022 Jan;67(1):337-343. Epub 2021 Feb 19 doi: 10.1007/s10620-021-06822-9. PMID: 33604792Free PMC Article
Chemotherapy of metastatic colon cancer in France: A population-based study.
Mas L, Bachet JB, Jooste V, Lepage C, Bouvier AM
Dig Liver Dis 2021 Oct;53(10):1334-1342. Epub 2021 Apr 14 doi: 10.1016/j.dld.2021.03.019. PMID: 33865721
(90)Y-microsphere radioembolization: The method, clinical evidence and perspective.
Spyridonidis T, Papathanasiou N, Spyridonidis J, Ntzoumani C, Spyropoulou D, Katsanos K, Apostolopoulos DJ
Hell J Nucl Med 2020 Sep-Dec;23(3):330-338. Epub 2020 Dec 14 doi: 10.1967/s002449912210. PMID: 33306761
Liver transplantation for colorectal liver metastases: What do we need to know?
Line PD, Ruffolo LI, Toso C, Dueland S, Nadalin S, Hernandez-Alejandro R
Int J Surg 2020 Oct;82S:87-92. Epub 2020 Apr 17 doi: 10.1016/j.ijsu.2020.03.079. PMID: 32305529
Hepatic progenitor cells in metastatic liver carcinomas.
Delladetsima I, Sakellariou S, Govaere O, Poulaki E, Felekouras E, Tiniakos D
Histopathology 2018 May;72(6):1060-1065. Epub 2018 Feb 14 doi: 10.1111/his.13450. PMID: 29220096

Diagnosis

Systematic review of isolated disseminated carcinomatosis of bone marrow from colorectal cancer.
Chan WK, Lin NS, Tay KV, Teo LT
ANZ J Surg 2023 May;93(5):1169-1175. Epub 2023 Feb 11 doi: 10.1111/ans.18324. PMID: 36772885
Role of Liver Biopsy in Assessment of Radiologically Identified Liver Masses.
Khalifa A, Sasso R, Rockey DC
Dig Dis Sci 2022 Jan;67(1):337-343. Epub 2021 Feb 19 doi: 10.1007/s10620-021-06822-9. PMID: 33604792Free PMC Article
Chemotherapy of metastatic colon cancer in France: A population-based study.
Mas L, Bachet JB, Jooste V, Lepage C, Bouvier AM
Dig Liver Dis 2021 Oct;53(10):1334-1342. Epub 2021 Apr 14 doi: 10.1016/j.dld.2021.03.019. PMID: 33865721
Gastrointestinal malignancy in cystic fibrosis.
Hough NE, Chapman SJ, Flight WG
Paediatr Respir Rev 2020 Sep;35:90-92. Epub 2020 Apr 9 doi: 10.1016/j.prrv.2020.03.002. PMID: 32505496
Patterns of metastasis in colon and rectal cancer.
Riihimäki M, Hemminki A, Sundquist J, Hemminki K
Sci Rep 2016 Jul 15;6:29765. doi: 10.1038/srep29765. PMID: 27416752Free PMC Article

Therapy

Selective Internal Radiation Therapy in the Multidisciplinary Management of Liver Metastases From Colorectal Carcinoma.
Tchelebi L, Sharma NK
Semin Nucl Med 2019 May;49(3):182-188. Epub 2019 Feb 14 doi: 10.1053/j.semnuclmed.2019.01.002. PMID: 30954183
Targeting PRPK Function Blocks Colon Cancer Metastasis.
Zykova T, Zhu F, Wang L, Li H, Lim DY, Yao K, Roh E, Yoon SP, Kim HG, Bae KB, Wen W, Shin SH, Nadas J, Li Y, Ma W, Bode AM, Dong Z
Mol Cancer Ther 2018 May;17(5):1101-1113. Epub 2018 Feb 26 doi: 10.1158/1535-7163.MCT-17-0628. PMID: 29483219Free PMC Article
Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer.
Bullman S, Pedamallu CS, Sicinska E, Clancy TE, Zhang X, Cai D, Neuberg D, Huang K, Guevara F, Nelson T, Chipashvili O, Hagan T, Walker M, Ramachandran A, Diosdado B, Serna G, Mulet N, Landolfi S, Ramon Y Cajal S, Fasani R, Aguirre AJ, Ng K, Élez E, Ogino S, Tabernero J, Fuchs CS, Hahn WC, Nuciforo P, Meyerson M
Science 2017 Dec 15;358(6369):1443-1448. Epub 2017 Nov 23 doi: 10.1126/science.aal5240. PMID: 29170280Free PMC Article
A new approach to the adoptive immunotherapy of cancer with tumor-infiltrating lymphocytes.
Rosenberg SA, Spiess P, Lafreniere R
Science 1986 Sep 19;233(4770):1318-21. doi: 10.1126/science.3489291. PMID: 3489291
Infusion-embolization.
Wallace S, Charnsangavej C, Carrasco CH, Bechtel W
Cancer 1984 Dec 1;54(11 Suppl):2751-65. doi: 10.1002/1097-0142(19841201)54:2+<2751::aid-cncr2820541423>3.0.co;2-5. PMID: 6093984

Prognosis

Surgery improves the prognosis of colon mucinous adenocarcinoma with liver metastases: a SEER-based study.
Huang J, Chen G, Liu H, Zhang Y, Tang R, Huang Q, Fu K, Peng X, Xiao S
BMC Cancer 2020 Sep 23;20(1):908. doi: 10.1186/s12885-020-07400-4. PMID: 32967651Free PMC Article
Gastrointestinal malignancy in cystic fibrosis.
Hough NE, Chapman SJ, Flight WG
Paediatr Respir Rev 2020 Sep;35:90-92. Epub 2020 Apr 9 doi: 10.1016/j.prrv.2020.03.002. PMID: 32505496
Metastatic patterns and survival outcomes in patients with stage IV colon cancer: A population-based analysis.
Wang J, Li S, Liu Y, Zhang C, Li H, Lai B
Cancer Med 2020 Jan;9(1):361-373. Epub 2019 Nov 6 doi: 10.1002/cam4.2673. PMID: 31693304Free PMC Article
Targeting PRPK Function Blocks Colon Cancer Metastasis.
Zykova T, Zhu F, Wang L, Li H, Lim DY, Yao K, Roh E, Yoon SP, Kim HG, Bae KB, Wen W, Shin SH, Nadas J, Li Y, Ma W, Bode AM, Dong Z
Mol Cancer Ther 2018 May;17(5):1101-1113. Epub 2018 Feb 26 doi: 10.1158/1535-7163.MCT-17-0628. PMID: 29483219Free PMC Article
Scan? Cure? Sure!
Goldberg RM, Ryan DP
Oncologist 2011;16(2):254-6. doi: 10.1634/theoncologist.2011-0014. PMID: 21349952Free PMC Article

Clinical prediction guides

Multi-omic analysis reveals metabolic pathways that characterize right-sided colon cancer liver metastasis.
Morris MT, Jain A, Sun B, Kurbatov V, Muca E, Zeng Z, Jin Y, Roper J, Lu J, Paty PB, Johnson CH, Khan SA
Cancer Lett 2023 Oct 10;574:216384. Epub 2023 Sep 14 doi: 10.1016/j.canlet.2023.216384. PMID: 37716465Free PMC Article
Gold Nanorods are Selective Cytotoxic Agents.
El Gendy M, Weinfeld M, Abdoon A
Anticancer Agents Med Chem 2022;22(5):991-998. doi: 10.2174/1871520621666210726130028. PMID: 34315395
Chemotherapy of metastatic colon cancer in France: A population-based study.
Mas L, Bachet JB, Jooste V, Lepage C, Bouvier AM
Dig Liver Dis 2021 Oct;53(10):1334-1342. Epub 2021 Apr 14 doi: 10.1016/j.dld.2021.03.019. PMID: 33865721
Robotic ALPPS.
Machado MAC, Surjan RC, Makdissi F
Ann Surg Oncol 2020 Apr;27(4):1174-1179. Epub 2019 Nov 4 doi: 10.1245/s10434-019-08027-x. PMID: 31686346
Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer.
Bullman S, Pedamallu CS, Sicinska E, Clancy TE, Zhang X, Cai D, Neuberg D, Huang K, Guevara F, Nelson T, Chipashvili O, Hagan T, Walker M, Ramachandran A, Diosdado B, Serna G, Mulet N, Landolfi S, Ramon Y Cajal S, Fasani R, Aguirre AJ, Ng K, Élez E, Ogino S, Tabernero J, Fuchs CS, Hahn WC, Nuciforo P, Meyerson M
Science 2017 Dec 15;358(6369):1443-1448. Epub 2017 Nov 23 doi: 10.1126/science.aal5240. PMID: 29170280Free PMC Article

Recent systematic reviews

Systematic review of isolated disseminated carcinomatosis of bone marrow from colorectal cancer.
Chan WK, Lin NS, Tay KV, Teo LT
ANZ J Surg 2023 May;93(5):1169-1175. Epub 2023 Feb 11 doi: 10.1111/ans.18324. PMID: 36772885
Electrocoagulation for liver metastases.
Storman D, Swierz MJ, Riemsma RP, Wolff R, Mitus JW, Pedziwiatr M, Kleijnen J, Bala MM
Cochrane Database Syst Rev 2021 Jan 28;1(1):CD009497. doi: 10.1002/14651858.CD009497.pub3. PMID: 33507555Free PMC Article
Cryotherapy for liver metastases.
Bala MM, Riemsma RP, Wolff R, Pedziwiatr M, Mitus JW, Storman D, Swierz MJ, Kleijnen J
Cochrane Database Syst Rev 2019 Jul 10;7(7):CD009058. doi: 10.1002/14651858.CD009058.pub3. PMID: 31291464Free PMC Article
Electro-coagulation for liver metastases.
Riemsma RP, Bala MM, Wolff R, Kleijnen J
Cochrane Database Syst Rev 2013 May 31;(5):CD009497. doi: 10.1002/14651858.CD009497.pub2. PMID: 23728692
Timing of hepatectomy in resectable synchronous colorectal liver metastases (SCRLM): Simultaneous or delayed?
Yin Z, Liu C, Chen Y, Bai Y, Shang C, Yin R, Yin D, Wang J
Hepatology 2013 Jun;57(6):2346-57. doi: 10.1002/hep.26283. PMID: 23359206

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