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Non-Small Cell Adenocarcinoma

MedGen UID:
233786
•Concept ID:
C1335060
•
Neoplastic Process
Synonym: Nonsmall Cell Adenocarcinoma

Definition

A carcinoma characterized by the presence of large adenocarcinoma cells. [from NCI]

Professional guidelines

PubMed

Molecular testing in lung cancer: fine-needle aspiration specimen adequacy and test prioritization prior to the CAP/IASLC/AMP Molecular Testing Guideline publication.
Rafael OC, Aziz M, Raftopoulos H, Vele OE, Xu W, Sugrue C
Cancer Cytopathol 2014 Jun;122(6):454-8. Epub 2014 Apr 10 doi: 10.1002/cncy.21426. PMID: 24723383

Recent clinical studies

Etiology

Capmatinib-Induced Pseudo-Acute Kidney Injury: A Case Report.
Mohan A, Herrmann SM
Am J Kidney Dis 2022 Jan;79(1):120-124. Epub 2021 Jun 9 doi: 10.1053/j.ajkd.2021.04.009. PMID: 34118303
Characterization of the cytotoxic effects of the combination of cisplatin and flavanol (-)-epicatechin on human lung cancer cell line A549. An isobolographic approach.
Varela-Castillo O, Cordero P, Gutiérrez-Iglesias G, Palma I, Rubio-Gayosso I, Meaney E, Ramirez-Sanchez I, Villarreal F, Ceballos G, Nájera N
Exp Oncol 2018 Mar;40(1):19-23. PMID: 29600977
Characterization of radiologically indeterminate lung lesions: 99mTc-depreotide SPECT versus 18F-FDG PET.
Ferran N, Ricart Y, Lopez M, Martinez-Ballarin I, Roca M, Gámez C, Carrerea D, Guirao S, Leon AF, Martin-Comin J
Nucl Med Commun 2006 Jun;27(6):507-14. doi: 10.1097/00006231-200606000-00006. PMID: 16710105

Diagnosis

Capmatinib-Induced Pseudo-Acute Kidney Injury: A Case Report.
Mohan A, Herrmann SM
Am J Kidney Dis 2022 Jan;79(1):120-124. Epub 2021 Jun 9 doi: 10.1053/j.ajkd.2021.04.009. PMID: 34118303
Characterization of radiologically indeterminate lung lesions: 99mTc-depreotide SPECT versus 18F-FDG PET.
Ferran N, Ricart Y, Lopez M, Martinez-Ballarin I, Roca M, Gámez C, Carrerea D, Guirao S, Leon AF, Martin-Comin J
Nucl Med Commun 2006 Jun;27(6):507-14. doi: 10.1097/00006231-200606000-00006. PMID: 16710105
Recurrent embolic strokes and cardiac valvular disease in a patient with non-small cell adenocarcinoma of lung.
Royter V, Cohen SN
J Neurol Sci 2006 Feb 15;241(1-2):99-101. Epub 2005 Nov 28 doi: 10.1016/j.jns.2005.10.008. PMID: 16318856
Regulation of O6-methylguanine-DNA methyltransferase by methionine in human tumour cells.
Kokkinakis DM, von Wronski MA, Vuong TH, Brent TP, Schold SC Jr
Br J Cancer 1997;75(6):779-88. doi: 10.1038/bjc.1997.141. PMID: 9062396Free PMC Article
The effect of doxorubicin on the glutathione content and viability of cultured human lung cancer cell lines A549 and GLC4 210.
al-Kabban M, Stewart MJ, Watson ID, Reglinski J
Clin Chim Acta 1990 Dec 24;194(2-3):121-9. doi: 10.1016/0009-8981(90)90127-e. PMID: 1965536

Therapy

Small-cell transformation of ALK-rearranged non-small-cell adenocarcinoma of the lung.
Balla A, Khan F, Hampel KJ, Aisner DL, Sidiropoulos N
Cold Spring Harb Mol Case Stud 2018 Apr;4(2) Epub 2018 Apr 2 doi: 10.1101/mcs.a002394. PMID: 29317428Free PMC Article
Massive hematuria from the bilateral upper urinary tract in a patient treated for advanced lung cancer with gefitinib.
Mori H, Ohno Y, Ito F, Funaguchi N, Yanase K, Endo J, Nakano M, Bai La BL, Minatoguchi S
Jpn J Clin Oncol 2010 Mar;40(3):263-6. Epub 2009 Nov 7 doi: 10.1093/jjco/hyp141. PMID: 19897850
Characterization of radiologically indeterminate lung lesions: 99mTc-depreotide SPECT versus 18F-FDG PET.
Ferran N, Ricart Y, Lopez M, Martinez-Ballarin I, Roca M, Gámez C, Carrerea D, Guirao S, Leon AF, Martin-Comin J
Nucl Med Commun 2006 Jun;27(6):507-14. doi: 10.1097/00006231-200606000-00006. PMID: 16710105
Inhibition of insulin-like growth factor-I receptor (IGF-IR) signaling and tumor cell growth by a fully human neutralizing anti-IGF-IR antibody.
Wang Y, Hailey J, Williams D, Wang Y, Lipari P, Malkowski M, Wang X, Xie L, Li G, Saha D, Ling WL, Cannon-Carlson S, Greenberg R, Ramos RA, Shields R, Presta L, Brams P, Bishop WR, Pachter JA
Mol Cancer Ther 2005 Aug;4(8):1214-21. doi: 10.1158/1535-7163.MCT-05-0048. PMID: 16093437
The effect of doxorubicin on the glutathione content and viability of cultured human lung cancer cell lines A549 and GLC4 210.
al-Kabban M, Stewart MJ, Watson ID, Reglinski J
Clin Chim Acta 1990 Dec 24;194(2-3):121-9. doi: 10.1016/0009-8981(90)90127-e. PMID: 1965536

Prognosis

Capmatinib-Induced Pseudo-Acute Kidney Injury: A Case Report.
Mohan A, Herrmann SM
Am J Kidney Dis 2022 Jan;79(1):120-124. Epub 2021 Jun 9 doi: 10.1053/j.ajkd.2021.04.009. PMID: 34118303
Massive hematuria from the bilateral upper urinary tract in a patient treated for advanced lung cancer with gefitinib.
Mori H, Ohno Y, Ito F, Funaguchi N, Yanase K, Endo J, Nakano M, Bai La BL, Minatoguchi S
Jpn J Clin Oncol 2010 Mar;40(3):263-6. Epub 2009 Nov 7 doi: 10.1093/jjco/hyp141. PMID: 19897850

Clinical prediction guides

Capmatinib-Induced Pseudo-Acute Kidney Injury: A Case Report.
Mohan A, Herrmann SM
Am J Kidney Dis 2022 Jan;79(1):120-124. Epub 2021 Jun 9 doi: 10.1053/j.ajkd.2021.04.009. PMID: 34118303
Characterization of the cytotoxic effects of the combination of cisplatin and flavanol (-)-epicatechin on human lung cancer cell line A549. An isobolographic approach.
Varela-Castillo O, Cordero P, Gutiérrez-Iglesias G, Palma I, Rubio-Gayosso I, Meaney E, Ramirez-Sanchez I, Villarreal F, Ceballos G, Nájera N
Exp Oncol 2018 Mar;40(1):19-23. PMID: 29600977

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