Minor Salivary Gland Mucoepidermoid Carcinoma

MedGen UID:: 233711
•Concept ID:: C1334773
•: Neoplastic Process

Synonyms:

Mucoepidermoid Carcinoma of Minor Salivary Gland; Mucoepidermoid Carcinoma of the Minor Salivary Gland

Definition

A carcinoma that arises from the minor salivary glands. It usually presents as a firm and painless mass. It is characterized by the presence of epidermoid cells, mucus producing cells, and cells of intermediate type. The majority of cases have a favorable outcome. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMinor Salivary Gland Mucoepidermoid Carcinoma

Head and Neck Disorder
- Disorder of salivary gland
  - Salivary gland neoplasm
    - Neoplasm of minor salivary gland
      - Malignant tumor of minor salivary gland
        Minor salivary gland carcinoma
        Minor Salivary Gland Mucoepidermoid Carcinoma

Professional guidelines

PubMed

Mucoepidermoid carcinoma of the major salivary glands: clinical and histopathologic analysis of 234 cases with evaluation of grading criteria.

Goode RK, Auclair PL, Ellis GL
Cancer 1998 Apr 1;82(7):1217-24. doi: 10.1002/(sici)1097-0142(19980401)82:7<1217::aid-cncr2>3.0.co;2-c. PMID: 9529011

See all (1)

Recent clinical studies

Etiology

Mucoepidermoid Carcinoma: A 23-Year Experience with Emphasis on Low-Grade Tumors with Close/Positive Margins.

Spellman J, Calzada G
Otolaryngol Head Neck Surg 2018 May;158(5):889-895. Epub 2018 Jan 9 doi: 10.1177/0194599817751072. PMID: 29313462

MUC4 and ERBB2 expression in major and minor salivary gland mucoepidermoid carcinoma.

Weed DT, Gomez-Fernandez C, Pacheco J, Ruiz J, Hamilton-Nelson K, Arnold DJ, Civantos FJ, Zhang J, Yasin M, Goodwin WJ, Carraway KL
Head Neck 2004 Apr;26(4):353-64. doi: 10.1002/hed.10387. PMID: 15054739

Mucoepidermoid carcinoma of the major salivary glands: clinical and histopathologic analysis of 234 cases with evaluation of grading criteria.

Goode RK, Auclair PL, Ellis GL
Cancer 1998 Apr 1;82(7):1217-24. doi: 10.1002/(sici)1097-0142(19980401)82:7<1217::aid-cncr2>3.0.co;2-c. PMID: 9529011

See all (3)

Diagnosis

Relationship between major and minor salivary gland mucoepidermoid carcinoma malignancy grading and presence of stromal myofibroblasts: immunohistochemical study.

Sobral AP, Loducca SV, Nunes FD, de Araújo NS, Kowalski LP, de Araújo VC
J Oral Pathol Med 2004 Jul;33(6):335-9. doi: 10.1111/j.1600-0714.2004.00111.x. PMID: 15200481

Mucoepidermoid carcinoma of the major salivary glands: clinical and histopathologic analysis of 234 cases with evaluation of grading criteria.

Goode RK, Auclair PL, Ellis GL
Cancer 1998 Apr 1;82(7):1217-24. doi: 10.1002/(sici)1097-0142(19980401)82:7<1217::aid-cncr2>3.0.co;2-c. PMID: 9529011

See all (2)

Prognosis

Mucoepidermoid Carcinoma: A 23-Year Experience with Emphasis on Low-Grade Tumors with Close/Positive Margins.

Spellman J, Calzada G
Otolaryngol Head Neck Surg 2018 May;158(5):889-895. Epub 2018 Jan 9 doi: 10.1177/0194599817751072. PMID: 29313462

Relationship between major and minor salivary gland mucoepidermoid carcinoma malignancy grading and presence of stromal myofibroblasts: immunohistochemical study.

Sobral AP, Loducca SV, Nunes FD, de Araújo NS, Kowalski LP, de Araújo VC
J Oral Pathol Med 2004 Jul;33(6):335-9. doi: 10.1111/j.1600-0714.2004.00111.x. PMID: 15200481

MUC4 and ERBB2 expression in major and minor salivary gland mucoepidermoid carcinoma.

Mucoepidermoid carcinoma of the major salivary glands: clinical and histopathologic analysis of 234 cases with evaluation of grading criteria.

Goode RK, Auclair PL, Ellis GL
Cancer 1998 Apr 1;82(7):1217-24. doi: 10.1002/(sici)1097-0142(19980401)82:7<1217::aid-cncr2>3.0.co;2-c. PMID: 9529011

See all (4)