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Lung Carcinoma Metastatic in the Bone

MedGen UID:
233627
•Concept ID:
C1334440
•
Neoplastic Process
Synonym: Lung Carcinoma Metastatic to the Bone

Definition

A carcinoma that arises from the lung and has metastasized to the bone. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLung Carcinoma Metastatic in the Bone

Professional guidelines

PubMed

Outcome of First-Line Treatment With Pembrolizumab According to KRAS/TP53 Mutational Status for Nonsquamous Programmed Death-Ligand 1-High (≥50%) NSCLC in the German National Network Genomic Medicine Lung Cancer.
Bischoff P, Reck M, Overbeck T, Christopoulos P, Rittmeyer A, Lüders H, Kollmeier J, Kulhavy J, Kemper M, Reinmuth N, Röper J, Janning M, Sommer L, Aguinarte L, Koch M, Wiesweg M, Wesseler C, Waller CF, Kauffmann-Guerrero D, Stenzinger A, Stephan-Falkenau S, Trautmann M, Lassmann S, Tiemann M, Klauschen F, Sebastian M, Griesinger F, Wolf J, Loges S, Frost N; National Network Genomic Medicine Lung Cancer (nNGM) Collaborator Group
J Thorac Oncol 2024 May;19(5):803-817. Epub 2023 Dec 13 doi: 10.1016/j.jtho.2023.12.015. PMID: 38096950
Management of Lung Cancer Presenting with Solitary Bone Metastasis.
Nistor CE, Ciuche A, Cucu AP, Nitipir C, Slavu C, Serban B, Cursaru A, Cretu B, Cirstoiu C
Medicina (Kaunas) 2022 Oct 16;58(10) doi: 10.3390/medicina58101463. PMID: 36295624Free PMC Article
Characterization, Prognosis, and Treatment of Patients With Metastatic Lung Carcinoid Tumors.
Robelin P, Hadoux J, Forestier J, Planchard D, Hervieu V, Berdelou A, Scoazec JY, Valette PJ, Leboulleux S, Ducreux M, Lombard-Bohas C, Baudin E, Walter T
J Thorac Oncol 2019 Jun;14(6):993-1002. Epub 2019 Feb 13 doi: 10.1016/j.jtho.2019.02.002. PMID: 30771520

Recent clinical studies

Etiology

Bone metastasis in esophageal adenocarcinoma and squamous cell carcinoma: a SEER-based study.
Qin Y, Mao J, Liang X, Wang N, Yuan M, Zhu J, Wu D, Wang Q
Gen Thorac Cardiovasc Surg 2022 May;70(5):479-490. Epub 2022 Jan 19 doi: 10.1007/s11748-021-01765-4. PMID: 35044634
Clinical features and outcomes of metastatic bone tumors of the pelvis.
Yang Q, Chen N, Fu W
J Int Med Res 2021 Jun;49(6):3000605211013152. doi: 10.1177/03000605211013152. PMID: 34154434Free PMC Article
The value of biomarkers in bone metastasis.
D'Oronzo S, Brown J, Coleman R
Eur J Cancer Care (Engl) 2017 Nov;26(6) Epub 2017 Jun 27 doi: 10.1111/ecc.12725. PMID: 28653449
Implications of bone metastases and the benefits of bone-targeted therapy.
Lipton A
Semin Oncol 2010 Oct;37 Suppl 2:S15-29. doi: 10.1053/j.seminoncol.2010.10.002. PMID: 21111244
Pulmonary hamartomas.
Gjevre JA, Myers JL, Prakash UB
Mayo Clin Proc 1996 Jan;71(1):14-20. doi: 10.4065/71.1.14. PMID: 8538225

Diagnosis

Challenging Diagnosis in NUT Carcinoma.
Claudia G, Alexandra G
Int J Surg Pathol 2021 Oct;29(7):722-725. Epub 2021 Jun 9 doi: 10.1177/10668969211019532. PMID: 34106022Free PMC Article
The role of PET/CT in the evaluation of skeletal metastases.
Kannivelu A, Loke KS, Kok TY, Osmany SY, Ali SZ, Suat-Jin L, Ng DC
Semin Musculoskelet Radiol 2014 Apr;18(2):149-65. Epub 2014 Apr 8 doi: 10.1055/s-0034-1371017. PMID: 24715447
Acrometastases.
Mavrogenis AF, Mimidis G, Kokkalis ZT, Karampi ES, Karampela I, Papagelopoulos PJ, Armaganidis A
Eur J Orthop Surg Traumatol 2014 Apr;24(3):279-83. Epub 2013 Sep 8 doi: 10.1007/s00590-013-1311-1. PMID: 24013815
Cortical bone metastases.
Coerkamp EG, Kroon HM
Radiology 1988 Nov;169(2):525-8. doi: 10.1148/radiology.169.2.3175002. PMID: 3175002
Acrometastases.
Bricout PB
J Natl Med Assoc 1981 Apr;73(4):325-9. PMID: 7218364Free PMC Article

Therapy

Characterization, Prognosis, and Treatment of Patients With Metastatic Lung Carcinoid Tumors.
Robelin P, Hadoux J, Forestier J, Planchard D, Hervieu V, Berdelou A, Scoazec JY, Valette PJ, Leboulleux S, Ducreux M, Lombard-Bohas C, Baudin E, Walter T
J Thorac Oncol 2019 Jun;14(6):993-1002. Epub 2019 Feb 13 doi: 10.1016/j.jtho.2019.02.002. PMID: 30771520
Surgical management of adrenocortical carcinoma.
Ranvier GG, Inabnet WB 3rd
Endocrinol Metab Clin North Am 2015 Jun;44(2):435-52. Epub 2015 Mar 17 doi: 10.1016/j.ecl.2015.02.008. PMID: 26038210
Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial.
Sternberg CN, Davis ID, Mardiak J, Szczylik C, Lee E, Wagstaff J, Barrios CH, Salman P, Gladkov OA, Kavina A, Zarbá JJ, Chen M, McCann L, Pandite L, Roychowdhury DF, Hawkins RE
J Clin Oncol 2010 Feb 20;28(6):1061-8. Epub 2010 Jan 25 doi: 10.1200/JCO.2009.23.9764. PMID: 20100962
Oncocytic adrenocortical carcinoma.
Tanaka K, Kumano Y, Kanomata N, Takeda M, Hara I, Fujisawa M, Kawabata G, Kamidono S
Urology 2004 Aug;64(2):376-7. doi: 10.1016/j.urology.2004.04.023. PMID: 15302503
Metastatic renal cell carcinoma.
Flanigan RC, Campbell SC, Clark JI, Picken MM
Curr Treat Options Oncol 2003 Oct;4(5):385-90. doi: 10.1007/s11864-003-0039-2. PMID: 12941198

Prognosis

Construction and Validation of Prognosis Nomogram for Metastatic Lung Squamous Cell Carcinoma: A Population-Based Study.
Liu Y, Sun M, Xiong Y, Gu X, Zhang K, Liu L
Technol Cancer Res Treat 2022 Jan-Dec;21:15330338221132035. doi: 10.1177/15330338221132035. PMID: 36217877Free PMC Article
Metastasis patterns and prognosis of octogenarians with metastatic breast cancer: A large-cohort retrospective study.
Lv Z, Zhang W, Zhang Y, Zhong G, Zhang X, Yang Q, Li Y
PLoS One 2022;17(2):e0263104. Epub 2022 Feb 17 doi: 10.1371/journal.pone.0263104. PMID: 35176034Free PMC Article
Metastatic Esophageal Carcinoma: Prognostic Factors and Survival.
Ghazy HF, El-Hadaad HA, Wahba HA, Abbas R, Abbas OA
J Gastrointest Cancer 2022 Jun;53(2):446-450. Epub 2021 Apr 13 doi: 10.1007/s12029-021-00610-4. PMID: 33847917
Acrometastases.
Mavrogenis AF, Mimidis G, Kokkalis ZT, Karampi ES, Karampela I, Papagelopoulos PJ, Armaganidis A
Eur J Orthop Surg Traumatol 2014 Apr;24(3):279-83. Epub 2013 Sep 8 doi: 10.1007/s00590-013-1311-1. PMID: 24013815
Metastatic orbital tumors.
Günalp I, Gündüz K
Jpn J Ophthalmol 1995;39(1):65-70. PMID: 7643486

Clinical prediction guides

Metastasis and recurrence patterns in the molecular subtypes of urothelial bladder cancer.
Sjödahl G, Eriksson P, Holmsten K, Abrahamsson J, Höglund M, Bernardo C, Ullén A, Liedberg F
Int J Cancer 2024 Jan 1;154(1):180-190. Epub 2023 Sep 6 doi: 10.1002/ijc.34715. PMID: 37671617
Specific organ metastases and prognosis in lung adenocarcinoma.
Zhao Z, Gao Y, Tan F, Xue Q, Gao S, He J
Thorac Cancer 2023 Mar;14(8):736-745. Epub 2023 Jan 24 doi: 10.1111/1759-7714.14801. PMID: 36694094Free PMC Article
Bone metastasis in esophageal adenocarcinoma and squamous cell carcinoma: a SEER-based study.
Qin Y, Mao J, Liang X, Wang N, Yuan M, Zhu J, Wu D, Wang Q
Gen Thorac Cardiovasc Surg 2022 May;70(5):479-490. Epub 2022 Jan 19 doi: 10.1007/s11748-021-01765-4. PMID: 35044634
Non-bone metastatic cancers promote osteocyte-induced bone destruction.
Pin F, Prideaux M, Huot JR, Essex AL, Plotkin LI, Bonetto A, Bonewald LF
Cancer Lett 2021 Nov 1;520:80-90. Epub 2021 Jul 4 doi: 10.1016/j.canlet.2021.06.030. PMID: 34233150Free PMC Article
The value of biomarkers in bone metastasis.
D'Oronzo S, Brown J, Coleman R
Eur J Cancer Care (Engl) 2017 Nov;26(6) Epub 2017 Jun 27 doi: 10.1111/ecc.12725. PMID: 28653449

Recent systematic reviews

Sensitivities evaluation of five radiopharmaceuticals in four common medullary thyroid carcinoma metastatic sites on PET/CT: a network meta-analysis and systematic review.
Li P, Zhang Y, Xu T, Zhu J, Wei T, Zhao W
Nucl Med Commun 2023 Dec 1;44(12):1114-1125. Epub 2023 Sep 29 doi: 10.1097/MNM.0000000000001773. PMID: 37769014Free PMC Article
Acrometastases to the Hand: A Systematic Review.
Umana GE, Scalia G, Palmisciano P, Passanisi M, Da Ros V, Pompili G, Barone F, Amico P, Tomasi SO, Graziano F, Patti IV, Mele S, Maugeri R, Raffa G, Giammalva GR, Iacopino GD, Germanò A, Nicoletti GF, Ippolito M, Sabini MG, Cicero S, Strigari L, Cuttone G
Medicina (Kaunas) 2021 Sep 9;57(9) doi: 10.3390/medicina57090950. PMID: 34577873Free PMC Article
Rare metastases of well-differentiated thyroid cancers: a systematic review.
Madani A, Jozaghi Y, Tabah R, How J, Mitmaker E
Ann Surg Oncol 2015 Feb;22(2):460-6. Epub 2014 Sep 6 doi: 10.1245/s10434-014-4058-y. PMID: 25192681
Outcomes of stereotactic radiotherapy for cranial and extracranial metastatic renal cell carcinoma: a systematic review.
Kothari G, Foroudi F, Gill S, Corcoran NM, Siva S
Acta Oncol 2015 Feb;54(2):148-57. Epub 2014 Aug 20 doi: 10.3109/0284186X.2014.939298. PMID: 25140860
Local treatments for metastases of renal cell carcinoma: a systematic review.
Dabestani S, Marconi L, Hofmann F, Stewart F, Lam TB, Canfield SE, Staehler M, Powles T, Ljungberg B, Bex A
Lancet Oncol 2014 Nov;15(12):e549-61. Epub 2014 Oct 26 doi: 10.1016/S1470-2045(14)70235-9. PMID: 25439697

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