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Lumbosacral lipoma

MedGen UID:: 232708
•Concept ID:: C1334438
•: Neoplastic Process

Synonyms:	lipoma of sacral region of vertebral column; Lumbosacral Lipoma; lumbosacral lipoma; sacral region of vertebral column lipoma

Monarch Initiative:	MONDO:0004077

Definition

A benign well-circumscribed tumor, composed of lobules of mature adipocytes, that arises within the lumbosacral tissue of the spine. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVLumbosacral lipoma

Neoplasm by Special Category
- Benign neoplasm
  - Benign connective and soft tissue neoplasm
    - Benign lipomatous neoplasm
      - Lipoma
        Deep Lipoma
        Lumbosacral lipoma

Professional guidelines

PubMed

Conservative and surgical treatment of pediatric asymptomatic lumbosacral lipoma: a meta-analysis.

Xiong Y, Yang L, Zhen W, Fangyong D, Feng W, Ting L
Neurosurg Rev 2018 Jul;41(3):737-743. Epub 2016 Oct 28 doi: 10.1007/s10143-016-0796-6. PMID: 27796602

The natural history and management of patients with congenital deficits associated with lumbosacral lipomas.

Tu A, Hengel R, Cochrane DD
Childs Nerv Syst 2016 Apr;32(4):667-73. Epub 2016 Jan 11 doi: 10.1007/s00381-015-3008-8. PMID: 26753902

Closed spinal dysraphism: a review on diagnosis and treatment in infancy.

Cornette L, Verpoorten C, Lagae L, Plets C, Van Calenbergh F, Casaer P
Eur J Paediatr Neurol 1998;2(4):179-85. doi: 10.1016/s1090-3798(98)80017-2. PMID: 10726589

See all (3)

Recent clinical studies

Etiology

Comparison of intraoperative neurophysiological monitoring methods for lumbosacral lipoma surgery in infants.

Nonaka M, Itakura T, Iwamura H, Ueno K, Naito N, Miyata M, Isozaki H, Li Y, Takeda J, Asai A
Childs Nerv Syst 2023 Jun;39(6):1603-1610. Epub 2023 Mar 4 doi: 10.1007/s00381-023-05900-9. PMID: 36869907

Does conus morphology have implications for outcome in lumbosacral lipoma?

Thompson DNP, Spoor J, Schotman M, Maestri S, Craven CL, Desai D
Childs Nerv Syst 2021 Jun;37(6):2025-2031. Epub 2021 Feb 18 doi: 10.1007/s00381-021-05081-3. PMID: 33604718

Whole spine MRI is not required in investigating uncomplicated paediatric lumbosacral lipoma. A retrospective single-institution review.

Layard Horsfall H, Chari A, Huttunen T, Simcock C, D'Arco F, Thompson D
Childs Nerv Syst 2019 Nov;35(11):2163-2169. Epub 2019 Sep 9 doi: 10.1007/s00381-019-04373-z. PMID: 31502036

Radical excision of lumbosacral lipoma: an early experience of "followers".

Chong S, Lee JY, Kim KH, Shin HI, Kim K, Park K, Kim SK, Wang KC
Childs Nerv Syst 2019 Sep;35(9):1591-1597. Epub 2019 May 31 doi: 10.1007/s00381-019-04212-1. PMID: 31152216

Closed spinal dysraphism: a review on diagnosis and treatment in infancy.

Cornette L, Verpoorten C, Lagae L, Plets C, Van Calenbergh F, Casaer P
Eur J Paediatr Neurol 1998;2(4):179-85. doi: 10.1016/s1090-3798(98)80017-2. PMID: 10726589

See all (28)

Diagnosis

Whole spine MRI is not required in investigating uncomplicated paediatric lumbosacral lipoma. A retrospective single-institution review.

Layard Horsfall H, Chari A, Huttunen T, Simcock C, D'Arco F, Thompson D
Childs Nerv Syst 2019 Nov;35(11):2163-2169. Epub 2019 Sep 9 doi: 10.1007/s00381-019-04373-z. PMID: 31502036

Antenatal diagnosis of spinal lipomas.

Thorne A, Pierre-Kahn A, Sonigo P
Childs Nerv Syst 2001 Dec;17(12):697-703. Epub 2001 Nov 24 doi: 10.1007/s00381-001-0525-4. PMID: 11862434

Closed spinal dysraphism: a review on diagnosis and treatment in infancy.

Cornette L, Verpoorten C, Lagae L, Plets C, Van Calenbergh F, Casaer P
Eur J Paediatr Neurol 1998;2(4):179-85. doi: 10.1016/s1090-3798(98)80017-2. PMID: 10726589

Occult spinal dysraphism.

Bajpai M, Kataria R, Gupta DK, Agarwala S
Indian J Pediatr 1997 Nov-Dec;64(6 Suppl):62-7. PMID: 11129883

Leptomyelolipoma: analysis of 20 cases.

Harrison MJ, Mitnick RJ, Rosenblum BR, Rothman AS
J Neurosurg 1990 Sep;73(3):360-7. doi: 10.3171/jns.1990.73.3.0360. PMID: 2384773

See all (30)

Therapy

Predictive value of intraoperative bulbocavernosus reflex during untethering surgery for post-operative voiding function.

Cha S, Wang KC, Park K, Shin HI, Lee JY, Chong S, Kim K
Clin Neurophysiol 2018 Dec;129(12):2594-2601. Epub 2018 Oct 30 doi: 10.1016/j.clinph.2018.09.026. PMID: 30448714

Conservative and surgical treatment of pediatric asymptomatic lumbosacral lipoma: a meta-analysis.

Xiong Y, Yang L, Zhen W, Fangyong D, Feng W, Ting L
Neurosurg Rev 2018 Jul;41(3):737-743. Epub 2016 Oct 28 doi: 10.1007/s10143-016-0796-6. PMID: 27796602

Spinal column shortening for tethered cord syndrome associated with myelomeningocele, lumbosacral lipoma, and lipomyelomeningocele in children and young adults.

Aldave G, Hansen D, Hwang SW, Moreno A, Briceño V, Jea A
J Neurosurg Pediatr 2017 Jun;19(6):703-710. Epub 2017 Mar 31 doi: 10.3171/2017.1.PEDS16533. PMID: 28362188

Results of the prophylactic surgery of lumbosacral lipomas 20 years of experience in the Paediatric Neurosurgery Department La Timone Enfants Hospital, Marseille, France.

da Rosa SP, Scavarda D, Choux M
Childs Nerv Syst 2016 Nov;32(11):2205-2209. Epub 2016 Aug 15 doi: 10.1007/s00381-016-3198-8. PMID: 27526098

Epilepsy in patients with spina bifida in the lumbosacral region.

Yoshida F, Morioka T, Hashiguchi K, Kawamura T, Miyagi Y, Nagata S, Mihara F, Ohshio M, Sasaki T
Neurosurg Rev 2006 Oct;29(4):327-32; discussion 332. Epub 2006 Aug 25 doi: 10.1007/s10143-006-0035-7. PMID: 16933125

See all (5)

Prognosis

Does conus morphology have implications for outcome in lumbosacral lipoma?

Thompson DNP, Spoor J, Schotman M, Maestri S, Craven CL, Desai D
Childs Nerv Syst 2021 Jun;37(6):2025-2031. Epub 2021 Feb 18 doi: 10.1007/s00381-021-05081-3. PMID: 33604718

Whole spine MRI is not required in investigating uncomplicated paediatric lumbosacral lipoma. A retrospective single-institution review.

Layard Horsfall H, Chari A, Huttunen T, Simcock C, D'Arco F, Thompson D
Childs Nerv Syst 2019 Nov;35(11):2163-2169. Epub 2019 Sep 9 doi: 10.1007/s00381-019-04373-z. PMID: 31502036

The natural history and management of patients with congenital deficits associated with lumbosacral lipomas.

Tu A, Hengel R, Cochrane DD
Childs Nerv Syst 2016 Apr;32(4):667-73. Epub 2016 Jan 11 doi: 10.1007/s00381-015-3008-8. PMID: 26753902

Closed spinal dysraphism: a review on diagnosis and treatment in infancy.

Cornette L, Verpoorten C, Lagae L, Plets C, Van Calenbergh F, Casaer P
Eur J Paediatr Neurol 1998;2(4):179-85. doi: 10.1016/s1090-3798(98)80017-2. PMID: 10726589

Occult spinal dysraphism.

Bajpai M, Kataria R, Gupta DK, Agarwala S
Indian J Pediatr 1997 Nov-Dec;64(6 Suppl):62-7. PMID: 11129883

See all (23)

Clinical prediction guides

Does conus morphology have implications for outcome in lumbosacral lipoma?

Thompson DNP, Spoor J, Schotman M, Maestri S, Craven CL, Desai D
Childs Nerv Syst 2021 Jun;37(6):2025-2031. Epub 2021 Feb 18 doi: 10.1007/s00381-021-05081-3. PMID: 33604718

Whole spine MRI is not required in investigating uncomplicated paediatric lumbosacral lipoma. A retrospective single-institution review.

Layard Horsfall H, Chari A, Huttunen T, Simcock C, D'Arco F, Thompson D
Childs Nerv Syst 2019 Nov;35(11):2163-2169. Epub 2019 Sep 9 doi: 10.1007/s00381-019-04373-z. PMID: 31502036

Radical excision of lumbosacral lipoma: an early experience of "followers".

Chong S, Lee JY, Kim KH, Shin HI, Kim K, Park K, Kim SK, Wang KC
Childs Nerv Syst 2019 Sep;35(9):1591-1597. Epub 2019 May 31 doi: 10.1007/s00381-019-04212-1. PMID: 31152216

Radiographic predictors of deterioration in patients with lumbosacral lipomas.

Tu A, Hengel AR, Cochrane DD
J Neurosurg Pediatr 2016 Aug;18(2):171-6. Epub 2016 Apr 15 doi: 10.3171/2016.1.PEDS15614. PMID: 27082975

The natural history and management of patients with congenital deficits associated with lumbosacral lipomas.

Tu A, Hengel R, Cochrane DD
Childs Nerv Syst 2016 Apr;32(4):667-73. Epub 2016 Jan 11 doi: 10.1007/s00381-015-3008-8. PMID: 26753902

See all (25)