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Conus medullaris neoplasm

MedGen UID:
232392
•Concept ID:
C1333153
•
Neoplastic Process
Synonyms: Conus Medullaris Neoplasm; conus medullaris neoplasm; conus medullaris neoplasm (disease); Conus Medullaris Tumor; conus medullaris tumor; conus medullaris tumour; Neoplasm of Conus Medullaris; neoplasm of conus medullaris; Neoplasm of the Conus Medullaris; neoplasm of the conus medullaris; Tumor of Conus Medullaris; tumor of conus medullaris; Tumor of the Conus Medullaris; tumor of the conus medullaris; tumour of conus medullaris; tumour of the conus medullaris
 
Monarch Initiative: MONDO:0002719

Definition

A neoplasm (disease) that involves the conus medullaris. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVConus medullaris neoplasm

Professional guidelines

PubMed

Primary central nervous system lymphoma.
Ferreri AJM, Calimeri T, Cwynarski K, Dietrich J, Grommes C, Hoang-Xuan K, Hu LS, Illerhaus G, Nayak L, Ponzoni M, Batchelor TT
Nat Rev Dis Primers 2023 Jun 15;9(1):29. doi: 10.1038/s41572-023-00439-0. PMID: 37322012Free PMC Article
Ependymoma: Evaluation and Management Updates.
Rudà R, Bruno F, Pellerino A, Soffietti R
Curr Oncol Rep 2022 Aug;24(8):985-993. Epub 2022 Apr 6 doi: 10.1007/s11912-022-01260-w. PMID: 35384591Free PMC Article
International Spine Radiosurgery Consortium consensus guidelines for target volume definition in spinal stereotactic radiosurgery.
Cox BW, Spratt DE, Lovelock M, Bilsky MH, Lis E, Ryu S, Sheehan J, Gerszten PC, Chang E, Gibbs I, Soltys S, Sahgal A, Deasy J, Flickinger J, Quader M, Mindea S, Yamada Y
Int J Radiat Oncol Biol Phys 2012 Aug 1;83(5):e597-605. Epub 2012 May 19 doi: 10.1016/j.ijrobp.2012.03.009. PMID: 22608954

Recent clinical studies

Etiology

Approach to Myelopathy and Myelitis.
Douglas AG, Xu DJ, Shah MP
Neurol Clin 2022 Feb;40(1):133-156. doi: 10.1016/j.ncl.2021.08.009. PMID: 34798966
Spinal Cord Tumor Surgery.
Walha S, Fairbanks SL
Anesthesiol Clin 2021 Mar;39(1):139-149. doi: 10.1016/j.anclin.2020.11.012. PMID: 33563377
Spinal Cord Tumor Microenvironment.
Rauschenbach L
Adv Exp Med Biol 2020;1226:97-109. doi: 10.1007/978-3-030-36214-0_8. PMID: 32030679
Natural history of spinal cavernous malformations.
Otten M, Mccormick P
Handb Clin Neurol 2017;143:233-239. doi: 10.1016/B978-0-444-63640-9.00022-9. PMID: 28552145
Spinal lipomas.
Blount JP, Elton S
Neurosurg Focus 2001 Jan 15;10(1):e3. doi: 10.3171/foc.2001.10.1.4. PMID: 16749755

Diagnosis

Spinal Cord Neoplasms.
McFaline-Figueroa JR
Continuum (Minneap Minn) 2024 Feb 1;30(1):99-118. doi: 10.1212/CON.0000000000001375. PMID: 38330474
Spinal Cord Anatomy and Localization.
Hardy TA
Continuum (Minneap Minn) 2021 Feb 1;27(1):12-29. doi: 10.1212/CON.0000000000000899. PMID: 33522735
Paraneoplastic myelopathy.
Flanagan EP, Keegan BM
Neurol Clin 2013 Feb;31(1):307-18. doi: 10.1016/j.ncl.2012.09.001. PMID: 23186906
Neoplastic myelopathy.
Nagpal S, Clarke JL
Semin Neurol 2012 Apr;32(2):137-45. Epub 2012 Sep 8 doi: 10.1055/s-0032-1322584. PMID: 22961188
Neuroschistosomiasis.
Carod-Artal FJ
Expert Rev Anti Infect Ther 2010 Nov;8(11):1307-18. doi: 10.1586/eri.10.111. PMID: 21073294

Therapy

Spinal Cord Reirradiation:Balancing Benefit Against Risks.
Pinkawa M
Int J Radiat Oncol Biol Phys 2021 Feb 1;109(2):312-313. doi: 10.1016/j.ijrobp.2019.05.067. PMID: 33422271
Adaptive radiotherapy for head and neck cancer.
Castelli J, Simon A, Lafond C, Perichon N, Rigaud B, Chajon E, De Bari B, Ozsahin M, Bourhis J, de Crevoisier R
Acta Oncol 2018 Oct;57(10):1284-1292. Epub 2018 Oct 5 doi: 10.1080/0284186X.2018.1505053. PMID: 30289291
Neuroschistosomiasis.
Carod-Artal FJ
Expert Rev Anti Infect Ther 2010 Nov;8(11):1307-18. doi: 10.1586/eri.10.111. PMID: 21073294
Myelopathies in patients with cancer.
Graber JJ, Nolan CP
Arch Neurol 2010 Mar;67(3):298-304. doi: 10.1001/archneurol.2010.20. PMID: 20212227
Parainfectious conus myelitis.
Pradhan S, Gupta RK, Kapoor R, Shashank S, Kathuria MK
J Neurol Sci 1998 Dec 11;161(2):156-62. doi: 10.1016/s0022-510x(98)00277-9. PMID: 9879697

Prognosis

Advances in Treatment of Diffuse Midline Gliomas.
Cacciotti C, Wright KD
Curr Neurol Neurosci Rep 2023 Dec;23(12):849-856. Epub 2023 Nov 3 doi: 10.1007/s11910-023-01317-8. PMID: 37921944
Intramedullary spinal cord lesions in children.
Hani U, Tebha SS, Bakhshi SK, Shamim MS
J Pak Med Assoc 2021 Feb;71(2(B)):775-777. PMID: 33941981
Neuroschistosomiasis.
Carod-Artal FJ
Expert Rev Anti Infect Ther 2010 Nov;8(11):1307-18. doi: 10.1586/eri.10.111. PMID: 21073294
Spinal lipomas.
Blount JP, Elton S
Neurosurg Focus 2001 Jan 15;10(1):e3. doi: 10.3171/foc.2001.10.1.4. PMID: 16749755
Spinal cord gliomas.
Henson JW
Curr Opin Neurol 2001 Dec;14(6):679-82. doi: 10.1097/00019052-200112000-00001. PMID: 11723373

Clinical prediction guides

Hemangioblastomas and Other Vascular Origating Tumors of Brain or Spinal Cord.
Vetrano IG, Gioppo A, Faragò G, Pinzi V, Pollo B, Broggi M, Schiariti M, Ferroli P, Acerbi F
Adv Exp Med Biol 2023;1405:377-403. doi: 10.1007/978-3-031-23705-8_14. PMID: 37452946
Intraoperative neurophysiology in intramedullary spinal cord tumor surgery.
Sala F, Skrap B, Kothbauer KF, Deletis V
Handb Clin Neurol 2022;186:229-244. doi: 10.1016/B978-0-12-819826-1.00019-3. PMID: 35772888
Spinal Hemangioblastomas and Neuropathic Pain.
Etli MU, Sarıkaya C, Onen MR, Naderi S
World Neurosurg 2021 May;149:e780-e784. Epub 2021 Feb 1 doi: 10.1016/j.wneu.2021.01.100. PMID: 33540101
Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy: A Review of the Literature.
Shan F, Long Y, Qiu W
Front Immunol 2018;9:2802. Epub 2018 Dec 5 doi: 10.3389/fimmu.2018.02802. PMID: 30568655Free PMC Article
Neuroschistosomiasis.
Carod-Artal FJ
Expert Rev Anti Infect Ther 2010 Nov;8(11):1307-18. doi: 10.1586/eri.10.111. PMID: 21073294

Recent systematic reviews

Clinical and neuroimaging phenotypes of autoimmune glial fibrillary acidic protein astrocytopathy: A systematic review and meta-analysis.
Hagbohm C, Ouellette R, Flanagan EP, Jonsson DI, Piehl F, Banwell B, Wickström R, Iacobaeus E, Granberg T, Ineichen BV
Eur J Neurol 2024 Jul;31(7):e16284. Epub 2024 Mar 20 doi: 10.1111/ene.16284. PMID: 38506182Free PMC Article
Non-demyelinating disorders mimicking and misdiagnosed as NMOSD: a literature review.
Zara P, Dinoto A, Carta S, Floris V, Turilli D, Budhram A, Ferrari S, Milia S, Solla P, Mariotto S, Flanagan EP, Lopez Chiriboga AS, Sechi E
Eur J Neurol 2023 Oct;30(10):3367-3376. Epub 2023 Jul 19 doi: 10.1111/ene.15983. PMID: 37433584Free PMC Article
Low Back Pain in the Emergency Department: Prevalence of Serious Spinal Pathologies and Diagnostic Accuracy of Red Flags.
Galliker G, Scherer DE, Trippolini MA, Rasmussen-Barr E, LoMartire R, Wertli MM
Am J Med 2020 Jan;133(1):60-72.e14. Epub 2019 Jul 3 doi: 10.1016/j.amjmed.2019.06.005. PMID: 31278933
Breast cancer (metastatic).
Stebbing J, Ngan S
BMJ Clin Evid 2010 Sep 8;2010 PMID: 21418674Free PMC Article
Breast cancer (metastatic).
Stebbing J, Slater S, Slevin M
BMJ Clin Evid 2007 Feb 1;2007 PMID: 19454050Free PMC Article

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