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Chronic Myelomonocytic Leukemia-2

MedGen UID:
232363
Concept ID:
C1333044
Neoplastic Process

Definition

A chronic myelomonocytic leukemia characterized by the presence of 10-19 percent blasts in the bone marrow and 5-19 percent blasts in the peripheral blood or by the presence of Auer rods regardless of the blasts count. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic Myelomonocytic Leukemia-2

Recent clinical studies

Etiology

Trujillo ÁM, Karduss AJ, Suarez G, Pérez R, Ruiz G, Cardona A, Ramírez M, Betancur J
Transplant Cell Ther 2021 May;27(5):427.e1-427.e7. Epub 2021 Feb 12 doi: 10.1016/j.jtct.2021.02.010. PMID: 33965184
Greipp PT, Dewald GW, Tefferi A
Cancer Genet Cytogenet 2004 Sep;153(2):170-2. doi: 10.1016/j.cancergencyto.2004.01.013. PMID: 15350308
Wiktor A, Rybicki BA, Piao ZS, Shurafa M, Barthel B, Maeda K, Van Dyke DL
Genes Chromosomes Cancer 2000 Jan;27(1):11-6. PMID: 10564581

Diagnosis

Gupta N, Roychoudry S, Sticco KL, Hsu P, Zhang X, Sheikh-Fayyaz S
Appl Immunohistochem Mol Morphol 2023 Apr 1;31(4):217-223. Epub 2023 Mar 6 doi: 10.1097/PAI.0000000000001115. PMID: 36867739Free PMC Article
Wiktor A, Rybicki BA, Piao ZS, Shurafa M, Barthel B, Maeda K, Van Dyke DL
Genes Chromosomes Cancer 2000 Jan;27(1):11-6. PMID: 10564581
Cox MC, Maffei L, Buffolino S, Del Poeta G, Venditti A, Cantonetti M, Aronica G, Aquilina P, Masi M, Amadori S
Am J Clin Pathol 1998 Jan;109(1):24-31. doi: 10.1093/ajcp/109.1.24. PMID: 9426514

Therapy

Trujillo ÁM, Karduss AJ, Suarez G, Pérez R, Ruiz G, Cardona A, Ramírez M, Betancur J
Transplant Cell Ther 2021 May;27(5):427.e1-427.e7. Epub 2021 Feb 12 doi: 10.1016/j.jtct.2021.02.010. PMID: 33965184
Yamada Y, Pinkston JA, Neriishi S, Ikeda S, Kinoshita K, Ichimaru M, Finch SC
Jpn J Clin Oncol 1983 Jun;13(2):343-52. PMID: 6887555

Prognosis

Vermi W, Facchetti F, Rosati S, Vergoni F, Rossi E, Festa S, Remotti D, Grigolato P, Massarelli G, Frizzera G
Am J Surg Pathol 2004 May;28(5):585-95. doi: 10.1097/00000478-200405000-00004. PMID: 15105645
Wiktor A, Rybicki BA, Piao ZS, Shurafa M, Barthel B, Maeda K, Van Dyke DL
Genes Chromosomes Cancer 2000 Jan;27(1):11-6. PMID: 10564581
Cox MC, Maffei L, Buffolino S, Del Poeta G, Venditti A, Cantonetti M, Aronica G, Aquilina P, Masi M, Amadori S
Am J Clin Pathol 1998 Jan;109(1):24-31. doi: 10.1093/ajcp/109.1.24. PMID: 9426514

Clinical prediction guides

Wiktor A, Rybicki BA, Piao ZS, Shurafa M, Barthel B, Maeda K, Van Dyke DL
Genes Chromosomes Cancer 2000 Jan;27(1):11-6. PMID: 10564581

Supplemental Content

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