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Disturbance in Bowel Function

MedGen UID:
232134
•Concept ID:
C1333310
•
Sign or Symptom

Definition

Abnormal functioning of the small and/or large intestine. [from NCI]

Professional guidelines

PubMed

Management of Chronic Diarrhea in Primary Care: The Gastroenterologists' Advice.
Hammer HF
Dig Dis 2021;39(6):615-621. Epub 2021 Feb 15 doi: 10.1159/000515219. PMID: 33588424
Mechanisms, Evaluation, and Management of Chronic Constipation.
Bharucha AE, Lacy BE
Gastroenterology 2020 Apr;158(5):1232-1249.e3. Epub 2020 Jan 13 doi: 10.1053/j.gastro.2019.12.034. PMID: 31945360Free PMC Article
Diagnosis, treatment, and prevention of cerebral palsy.
O'Shea TM
Clin Obstet Gynecol 2008 Dec;51(4):816-28. doi: 10.1097/GRF.0b013e3181870ba7. PMID: 18981805Free PMC Article

Recent clinical studies

Etiology

Irritable bowel syndrome.
Ford AC, Sperber AD, Corsetti M, Camilleri M
Lancet 2020 Nov 21;396(10263):1675-1688. Epub 2020 Oct 10 doi: 10.1016/S0140-6736(20)31548-8. PMID: 33049223
Constipation and Fecal Incontinence in the Elderly.
Deb B, Prichard DO, Bharucha AE
Curr Gastroenterol Rep 2020 Aug 24;22(11):54. doi: 10.1007/s11894-020-00791-1. PMID: 32839874
Pathophysiology of irritable bowel syndrome.
Holtmann GJ, Ford AC, Talley NJ
Lancet Gastroenterol Hepatol 2016 Oct;1(2):133-146. Epub 2016 Sep 8 doi: 10.1016/S2468-1253(16)30023-1. PMID: 28404070
The diagnostic approach to monogenic very early onset inflammatory bowel disease.
Uhlig HH, Schwerd T, Koletzko S, Shah N, Kammermeier J, Elkadri A, Ouahed J, Wilson DC, Travis SP, Turner D, Klein C, Snapper SB, Muise AM; COLORS in IBD Study Group and NEOPICS
Gastroenterology 2014 Nov;147(5):990-1007.e3. Epub 2014 Jul 21 doi: 10.1053/j.gastro.2014.07.023. PMID: 25058236Free PMC Article
Diagnosis, treatment, and prevention of cerebral palsy.
O'Shea TM
Clin Obstet Gynecol 2008 Dec;51(4):816-28. doi: 10.1097/GRF.0b013e3181870ba7. PMID: 18981805Free PMC Article

Diagnosis

Irritable bowel syndrome.
Ford AC, Sperber AD, Corsetti M, Camilleri M
Lancet 2020 Nov 21;396(10263):1675-1688. Epub 2020 Oct 10 doi: 10.1016/S0140-6736(20)31548-8. PMID: 33049223
Constipation and Fecal Incontinence in the Elderly.
Deb B, Prichard DO, Bharucha AE
Curr Gastroenterol Rep 2020 Aug 24;22(11):54. doi: 10.1007/s11894-020-00791-1. PMID: 32839874
Mechanisms, Evaluation, and Management of Chronic Constipation.
Bharucha AE, Lacy BE
Gastroenterology 2020 Apr;158(5):1232-1249.e3. Epub 2020 Jan 13 doi: 10.1053/j.gastro.2019.12.034. PMID: 31945360Free PMC Article
Pathophysiology of irritable bowel syndrome.
Holtmann GJ, Ford AC, Talley NJ
Lancet Gastroenterol Hepatol 2016 Oct;1(2):133-146. Epub 2016 Sep 8 doi: 10.1016/S2468-1253(16)30023-1. PMID: 28404070
Diagnosis, treatment, and prevention of cerebral palsy.
O'Shea TM
Clin Obstet Gynecol 2008 Dec;51(4):816-28. doi: 10.1097/GRF.0b013e3181870ba7. PMID: 18981805Free PMC Article

Therapy

Disturbances of the Gut Microbiota and Microbiota-Derived Metabolites in Inflammatory Bowel Disease.
Hu Y, Chen Z, Xu C, Kan S, Chen D
Nutrients 2022 Dec 2;14(23) doi: 10.3390/nu14235140. PMID: 36501169Free PMC Article
Irritable bowel syndrome.
Ford AC, Sperber AD, Corsetti M, Camilleri M
Lancet 2020 Nov 21;396(10263):1675-1688. Epub 2020 Oct 10 doi: 10.1016/S0140-6736(20)31548-8. PMID: 33049223
Mechanisms, Evaluation, and Management of Chronic Constipation.
Bharucha AE, Lacy BE
Gastroenterology 2020 Apr;158(5):1232-1249.e3. Epub 2020 Jan 13 doi: 10.1053/j.gastro.2019.12.034. PMID: 31945360Free PMC Article
Pathophysiology of irritable bowel syndrome.
Holtmann GJ, Ford AC, Talley NJ
Lancet Gastroenterol Hepatol 2016 Oct;1(2):133-146. Epub 2016 Sep 8 doi: 10.1016/S2468-1253(16)30023-1. PMID: 28404070
Anterior resection syndrome.
Bryant CL, Lunniss PJ, Knowles CH, Thaha MA, Chan CL
Lancet Oncol 2012 Sep;13(9):e403-8. doi: 10.1016/S1470-2045(12)70236-X. PMID: 22935240

Prognosis

Irritable bowel syndrome.
Ford AC, Sperber AD, Corsetti M, Camilleri M
Lancet 2020 Nov 21;396(10263):1675-1688. Epub 2020 Oct 10 doi: 10.1016/S0140-6736(20)31548-8. PMID: 33049223
Towards a Food Pharmacy: Immunologic Modulation through Diet.
Molendijk I, van der Marel S, Maljaars PWJ
Nutrients 2019 May 31;11(6) doi: 10.3390/nu11061239. PMID: 31159179Free PMC Article
The diagnostic approach to monogenic very early onset inflammatory bowel disease.
Uhlig HH, Schwerd T, Koletzko S, Shah N, Kammermeier J, Elkadri A, Ouahed J, Wilson DC, Travis SP, Turner D, Klein C, Snapper SB, Muise AM; COLORS in IBD Study Group and NEOPICS
Gastroenterology 2014 Nov;147(5):990-1007.e3. Epub 2014 Jul 21 doi: 10.1053/j.gastro.2014.07.023. PMID: 25058236Free PMC Article
Anterior resection syndrome.
Bryant CL, Lunniss PJ, Knowles CH, Thaha MA, Chan CL
Lancet Oncol 2012 Sep;13(9):e403-8. doi: 10.1016/S1470-2045(12)70236-X. PMID: 22935240
Diagnosis, treatment, and prevention of cerebral palsy.
O'Shea TM
Clin Obstet Gynecol 2008 Dec;51(4):816-28. doi: 10.1097/GRF.0b013e3181870ba7. PMID: 18981805Free PMC Article

Clinical prediction guides

Pasteurized akkermansia muciniphila improves irritable bowel syndrome-like symptoms and related behavioral disorders in mice.
Meynier M, Daugey V, Mallaret G, Gervason S, Meleine M, Barbier J, Aissouni Y, Lolignier S, Bonnet M, Ardid D, De Vos WM, Van Hul M, Suenaert P, Brochot A, Cani PD, Carvalho FA
Gut Microbes 2024 Jan-Dec;16(1):2298026. Epub 2024 Jan 3 doi: 10.1080/19490976.2023.2298026. PMID: 38170633Free PMC Article
Intestinal Barrier and Gut Microbiota in Patients with Overlapping Irritable Bowel Syndrome and Functional Dyspepsia.
Kovaleva A, Poluektova E, Maslennikov R, Karchevskaya A, Shifrin O, Kiryukhin A, Tertychnyy A, Kovalev L, Kovaleva M, Lobanova O, Kudryavtseva A, Krasnov G, Ivashkin V
Dig Dis Sci 2023 Nov;68(11):4166-4174. Epub 2023 Sep 26 doi: 10.1007/s10620-023-08117-7. PMID: 37752368
Role of the duodenal microbiota in functional dyspepsia.
Brown G, Hoedt EC, Keely S, Shah A, Walker MM, Holtmann G, Talley NJ
Neurogastroenterol Motil 2022 Nov;34(11):e14372. Epub 2022 Apr 11 doi: 10.1111/nmo.14372. PMID: 35403776Free PMC Article
The diagnostic approach to monogenic very early onset inflammatory bowel disease.
Uhlig HH, Schwerd T, Koletzko S, Shah N, Kammermeier J, Elkadri A, Ouahed J, Wilson DC, Travis SP, Turner D, Klein C, Snapper SB, Muise AM; COLORS in IBD Study Group and NEOPICS
Gastroenterology 2014 Nov;147(5):990-1007.e3. Epub 2014 Jul 21 doi: 10.1053/j.gastro.2014.07.023. PMID: 25058236Free PMC Article
Diagnosis, treatment, and prevention of cerebral palsy.
O'Shea TM
Clin Obstet Gynecol 2008 Dec;51(4):816-28. doi: 10.1097/GRF.0b013e3181870ba7. PMID: 18981805Free PMC Article

Recent systematic reviews

Menstrual Dysfunction in Adolescents with Chronic Illness: A Systematic Review.
Hobbs AK, Cheng HL, Tee EYF, Steinbeck KS
J Pediatr Adolesc Gynecol 2023 Aug;36(4):338-348. Epub 2023 May 14 doi: 10.1016/j.jpag.2023.05.005. PMID: 37192680
Utility of postoperative anorectal manometry in children with anorectal malformation: a systematic review.
Rajasegaran S, Tan WS, Ezrien DE, Sanmugam A, Singaravel S, Nah SA
Pediatr Surg Int 2022 Aug;38(8):1089-1097. Epub 2022 Jun 21 doi: 10.1007/s00383-022-05152-9. PMID: 35727358
Management of Chronic Diarrhea in Primary Care: The Gastroenterologists' Advice.
Hammer HF
Dig Dis 2021;39(6):615-621. Epub 2021 Feb 15 doi: 10.1159/000515219. PMID: 33588424
Systematic review: exercise-induced gastrointestinal syndrome-implications for health and intestinal disease.
Costa RJS, Snipe RMJ, Kitic CM, Gibson PR
Aliment Pharmacol Ther 2017 Aug;46(3):246-265. Epub 2017 Jun 7 doi: 10.1111/apt.14157. PMID: 28589631
Systematic review: anal and rectal changes after radiotherapy for prostate cancer.
Krol R, Smeenk RJ, van Lin EN, Yeoh EE, Hopman WP
Int J Colorectal Dis 2014 Mar;29(3):273-83. Epub 2013 Oct 23 doi: 10.1007/s00384-013-1784-8. PMID: 24150230

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