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Borderline Ovarian Endometrioid Cystadenofibroma

MedGen UID:
231956
•Concept ID:
C1332595
•
Neoplastic Process
Synonyms: Borderline Malignancy Ovarian Endometrioid Cystadenofibroma; Low Malignant Potential Ovarian Endometrioid Cystadenofibroma

Definition

An epithelial neoplasm that arises from the ovary characterized by the presence of cystic spaces which are lined by atypical glandular epithelial cells resembling endometrial cells. The surrounding ovarian stroma is fibrotic. There is no evidence of stromal invasion. [from NCI]

Recent clinical studies

Therapy

An unusual case of a borderline Brenner tumor associated with bilateral serous cystadenoma and endometrial carcinoma.
Cruz-Galarza D, Pérez-Rodríguez O, Laboy-Torres J, Gutiérrez-Rivera S
Bol Asoc Med P R 2014;106(1):54-6. PMID: 24791367

Prognosis

MRI of Borderline Epithelial Ovarian Tumors: Pathologic Correlation and Diagnostic Challenges.
Tsuboyama T, Sato K, Ota T, Fukui H, Onishi H, Nakamoto A, Tatsumi M, Tomiyama N
Radiographics 2022 Nov-Dec;42(7):2095-2111. Epub 2022 Sep 9 doi: 10.1148/rg.220068. PMID: 36083804
TFF3 Expression as Stratification Marker in Borderline Epithelial Tumors of the Ovary.
El-Balat A, Schmeil I, Karn T, Becker S, Sänger N, Holtrich U, Arsenic R
Pathol Oncol Res 2018 Apr;24(2):277-282. Epub 2017 May 3 doi: 10.1007/s12253-017-0240-4. PMID: 28470574
Ovarian masses with papillary projections diagnosed and removed during pregnancy: ultrasound features and histological diagnosis.
Mascilini F, Savelli L, Scifo MC, Exacoustos C, Timor-Tritsch IE, De Blasis I, Moruzzi MC, Pasciuto T, Scambia G, Valentin L, Testa AC
Ultrasound Obstet Gynecol 2017 Jul;50(1):116-123. doi: 10.1002/uog.17216. PMID: 27484484
Atypical and borderline endometrioid adenofibromas of the ovary. A report of 27 cases.
Bell DA, Scully RE
Am J Surg Pathol 1985 Mar;9(3):205-14. doi: 10.1097/00000478-198503000-00004. PMID: 3993832
On the histogenesis and morphology of ovarian carcinomas.
Dallenbach-Hellweg G
J Cancer Res Clin Oncol 1984;107(2):71-80. doi: 10.1007/BF00399375. PMID: 6715398

Clinical prediction guides

MRI of Borderline Epithelial Ovarian Tumors: Pathologic Correlation and Diagnostic Challenges.
Tsuboyama T, Sato K, Ota T, Fukui H, Onishi H, Nakamoto A, Tatsumi M, Tomiyama N
Radiographics 2022 Nov-Dec;42(7):2095-2111. Epub 2022 Sep 9 doi: 10.1148/rg.220068. PMID: 36083804
TFF3 Expression as Stratification Marker in Borderline Epithelial Tumors of the Ovary.
El-Balat A, Schmeil I, Karn T, Becker S, Sänger N, Holtrich U, Arsenic R
Pathol Oncol Res 2018 Apr;24(2):277-282. Epub 2017 May 3 doi: 10.1007/s12253-017-0240-4. PMID: 28470574
Ovarian masses with papillary projections diagnosed and removed during pregnancy: ultrasound features and histological diagnosis.
Mascilini F, Savelli L, Scifo MC, Exacoustos C, Timor-Tritsch IE, De Blasis I, Moruzzi MC, Pasciuto T, Scambia G, Valentin L, Testa AC
Ultrasound Obstet Gynecol 2017 Jul;50(1):116-123. doi: 10.1002/uog.17216. PMID: 27484484
Carcinoma of extrahepatic bile ducts and gallbladder metastatic to the ovary: a report of 16 cases.
Khunamornpong S, Lerwill MF, Siriaunkgul S, Suprasert P, Pojchamarnwiputh S, Chiangmai WN, Young RH
Int J Gynecol Pathol 2008 Jul;27(3):366-79. doi: 10.1097/PGP.0b013e31815d6903. PMID: 18580314
On the histogenesis and morphology of ovarian carcinomas.
Dallenbach-Hellweg G
J Cancer Res Clin Oncol 1984;107(2):71-80. doi: 10.1007/BF00399375. PMID: 6715398

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