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AIDS-Related Anal Carcinoma

MedGen UID:
231324
Concept ID:
C1332038
Neoplastic Process
Synonym: AIDS-Related Anal Cancer

Definition

A carcinoma arising from the anus and occurring in HIV-positive patients. Homosexual HIV-positive men have an increased risk of developing anal squamous cell carcinoma in comparison to the general male population. Sexually transmitted human papillomavirus is detected in the majority of the cases. [from NCI]

Professional guidelines

PubMed

Goldschmidt R, Chu C
Am Fam Physician 2021 Apr 1;103(7):407-416. PMID: 33788514
Carbone A, Vaccher E, Gloghini A, Pantanowitz L, Abayomi A, de Paoli P, Franceschi S
Nat Rev Clin Oncol 2014 Apr;11(4):223-38. Epub 2014 Mar 11 doi: 10.1038/nrclinonc.2014.31. PMID: 24614140
Greene MD
Nurse Pract 2009 May;34(5):45-51. doi: 10.1097/01.NPR.0000350571.53729.74. PMID: 19390399

Recent clinical studies

Etiology

Dube Mandishora RS, Rounge TB, Fitzpatrick M, Christiansen IK, Ambur OH, Lagström S, Stray-Pedersen B, Tommasino M, Palefsky J, Chirenje ZM
PLoS One 2021;16(4):e0250426. Epub 2021 Apr 26 doi: 10.1371/journal.pone.0250426. PMID: 33901223Free PMC Article
Riedel DJ, Tang LS, Rositch AF
Curr HIV/AIDS Rep 2015 Sep;12(3):362-72. doi: 10.1007/s11904-015-0276-6. PMID: 26152660Free PMC Article
Kan M, Wong PH, Press N, Wiseman SM
Expert Rev Anticancer Ther 2014 Apr;14(4):395-405. Epub 2014 Feb 9 doi: 10.1586/14737140.2013.877843. PMID: 24506785
Vazquez E
Posit Aware 1996 Sep-Oct;7(5):12-3. PMID: 11363782
Rabkin CS
Curr Opin Oncol 1994 Sep;6(5):492-6. doi: 10.1097/00001622-199409000-00008. PMID: 7827152

Diagnosis

Goldschmidt R, Chu C
Am Fam Physician 2021 Apr 1;103(7):407-416. PMID: 33788514
Carbone A, Vaccher E, Gloghini A, Pantanowitz L, Abayomi A, de Paoli P, Franceschi S
Nat Rev Clin Oncol 2014 Apr;11(4):223-38. Epub 2014 Mar 11 doi: 10.1038/nrclinonc.2014.31. PMID: 24614140
Kan M, Wong PH, Press N, Wiseman SM
Expert Rev Anticancer Ther 2014 Apr;14(4):395-405. Epub 2014 Feb 9 doi: 10.1586/14737140.2013.877843. PMID: 24506785
Cachay ER, Mathews WC
AIDS Rev 2013 Apr-Jun;15(2):122-33. PMID: 23681437
Vazquez E
Posit Aware 1996 Sep-Oct;7(5):12-3. PMID: 11363782

Therapy

Goldschmidt R, Chu C
Am Fam Physician 2021 Apr 1;103(7):407-416. PMID: 33788514
Carbone A, Vaccher E, Gloghini A, Pantanowitz L, Abayomi A, de Paoli P, Franceschi S
Nat Rev Clin Oncol 2014 Apr;11(4):223-38. Epub 2014 Mar 11 doi: 10.1038/nrclinonc.2014.31. PMID: 24614140
Tirelli U, Bernardi D, Spina M, Vaccher E
Crit Rev Oncol Hematol 2002 Mar;41(3):299-315. doi: 10.1016/s1040-8428(01)00165-2. PMID: 11880206
Martin F, Bower M
Sex Transm Infect 2001 Oct;77(5):327-31. doi: 10.1136/sti.77.5.327. PMID: 11588276Free PMC Article
Cottrill CP, Bottomley DM, Phillips RH
Clin Oncol (R Coll Radiol) 1997;9(6):365-80. doi: 10.1016/s0936-6555(97)80129-x. PMID: 9448965

Prognosis

Wells J, Flowers L, Mehta CC, Chandler R, Knott R, McDonnell Holstad M, Watkins Bruner D
AIDS Patient Care STDS 2022 Jul;36(7):263-271. Epub 2022 Jun 21 doi: 10.1089/apc.2022.0057. PMID: 35727648Free PMC Article
Kan M, Wong PH, Press N, Wiseman SM
Expert Rev Anticancer Ther 2014 Apr;14(4):395-405. Epub 2014 Feb 9 doi: 10.1586/14737140.2013.877843. PMID: 24506785
Cachay ER, Mathews WC
AIDS Rev 2013 Apr-Jun;15(2):122-33. PMID: 23681437
Martin F, Bower M
Sex Transm Infect 2001 Oct;77(5):327-31. doi: 10.1136/sti.77.5.327. PMID: 11588276Free PMC Article
Biggar RJ
Oncology (Williston Park) 2001 Apr;15(4):439-48; discussion 448-9. PMID: 11346932

Clinical prediction guides

Zucchetto A, Virdone S, Taborelli M, Grande E, Camoni L, Pappagallo M, Regine V, Grippo F, Polesel J, Dal Maso L, Suligoi B, Frova L, Serraino D
J Acquir Immune Defic Syndr 2016 Oct 1;73(2):190-6. doi: 10.1097/QAI.0000000000001033. PMID: 27116048
Dal Maso L, Suligoi B, Franceschi S, Braga C, Buzzoni C, Polesel J, Zucchetto A, Piselli P, Falcini F, Caldarella A, Zanetti R, Vercelli M, Guzzinati S, Russo A, Tagliabue G, Iachetta F, Ferretti S, Limina RM, Mangone L, Michiara M, Stracci F, Pirino DR, Piffer S, Giacomin A, Vitarelli S, Mazzoleni G, Iannelli A, Contrino ML, Fusco M, Tumino R, Fanetti AC, De Paoli P, Decarli A, Serraino D; Cancer and AIDS Registries Linkage Study
J Acquir Immune Defic Syndr 2014 Aug 1;66(4):428-35. doi: 10.1097/QAI.0000000000000184. PMID: 24798769
Cranston RD, Hart SD, Gornbein JA, Hirschowitz SL, Cortina G, Moe AA
Int J STD AIDS 2007 Feb;18(2):77-80. doi: 10.1258/095646207779949772. PMID: 17331275
Martin F, Bower M
Sex Transm Infect 2001 Oct;77(5):327-31. doi: 10.1136/sti.77.5.327. PMID: 11588276Free PMC Article
Thomas JO
Semin Oncol 2001 Apr;28(2):198-206. doi: 10.1016/s0093-7754(01)90092-2. PMID: 11301383

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