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Chronic polyneuropathy

MedGen UID:
223911
•Concept ID:
C1167650
•
Disease or Syndrome
Synonyms: Chronic Polyneuropathy; chronic polyneuropathy; polyneuropathy, chronic
 
Monarch Initiative: MONDO:0003335

Definition

Polyneuropathy that is persistent or long-standing in nature. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic polyneuropathy

Professional guidelines

PubMed

Which patients discontinue? Issues on Levodopa/carbidopa intestinal gel treatment: Italian multicentre survey of 905 patients with long-term follow-up.
Sensi M, Cossu G, Mancini F, Pilleri M, Zibetti M, Modugno N, Quatrale R, Tamma F, Antonini A; ITALIAN LEVODOPA CARBIDOPA INTESTINAL GEL WORKING GROUP
Parkinsonism Relat Disord 2017 May;38:90-92. Epub 2017 Feb 21 doi: 10.1016/j.parkreldis.2017.02.020. PMID: 28238650
Diagnostic investigation of patients with chronic polyneuropathy: evaluation of a clinical guideline.
Rosenberg NR, Portegies P, de Visser M, Vermeulen M
J Neurol Neurosurg Psychiatry 2001 Aug;71(2):205-9. doi: 10.1136/jnnp.71.2.205. PMID: 11459893Free PMC Article
Comparison of electrodiagnostic criteria for primary demyelination in chronic polyneuropathy.
Bromberg MB
Muscle Nerve 1991 Oct;14(10):968-76. doi: 10.1002/mus.880141007. PMID: 1944409

Recent clinical studies

Etiology

Statins do not increase risk of polyneuropathy: A case-control study and literature review.
Warendorf JK, Vrancken AFJE, van Eijk RPA, Visser NA, van den Berg LH, Notermans NC
Neurology 2019 Apr 30;92(18):e2136-e2144. Epub 2019 Feb 8 doi: 10.1212/WNL.0000000000007148. PMID: 30737334
Peripheral neuropathies.
Hanewinckel R, Ikram MA, Van Doorn PA
Handb Clin Neurol 2016;138:263-82. doi: 10.1016/B978-0-12-802973-2.00015-X. PMID: 27637963
The epidemiology and risk factors of chronic polyneuropathy.
Hanewinckel R, van Oijen M, Ikram MA, van Doorn PA
Eur J Epidemiol 2016 Jan;31(1):5-20. Epub 2015 Dec 23 doi: 10.1007/s10654-015-0094-6. PMID: 26700499Free PMC Article
Intravenous immunoglobulin for Guillain-Barré syndrome.
Hughes RA, Swan AV, van Doorn PA
Cochrane Database Syst Rev 2014 Sep 19;2014(9):CD002063. doi: 10.1002/14651858.CD002063.pub6. PMID: 25238327Free PMC Article
Infectious neuropathy.
de Freitas MR
Curr Opin Neurol 2007 Oct;20(5):548-52. doi: 10.1097/WCO.0b013e32826fbca6. PMID: 17885443

Diagnosis

Peripheral neuropathies.
Hanewinckel R, Ikram MA, Van Doorn PA
Handb Clin Neurol 2016;138:263-82. doi: 10.1016/B978-0-12-802973-2.00015-X. PMID: 27637963
The epidemiology and risk factors of chronic polyneuropathy.
Hanewinckel R, van Oijen M, Ikram MA, van Doorn PA
Eur J Epidemiol 2016 Jan;31(1):5-20. Epub 2015 Dec 23 doi: 10.1007/s10654-015-0094-6. PMID: 26700499Free PMC Article
Infectious neuropathies.
Sindic CJ
Curr Opin Neurol 2013 Oct;26(5):510-5. doi: 10.1097/WCO.0b013e328364c036. PMID: 23945279
Infectious neuropathy.
de Freitas MR
Curr Opin Neurol 2007 Oct;20(5):548-52. doi: 10.1097/WCO.0b013e32826fbca6. PMID: 17885443
Acquired peripheral neuropathy.
Chalk CH
Neurol Clin 1997 Aug;15(3):501-28. doi: 10.1016/s0733-8619(05)70331-5. PMID: 9227950

Therapy

Efficacy of azathioprine and methotrexate in patients with chronic inflammatory demyelinating polyneuropathy (CIDP).
Mehreen S, Iftikhar S, Muhammad A, Aatif Siddique R, Shahid S
Pak J Pharm Sci 2023 Jul;36(4(Special)):1361-1365. PMID: 37606029
Chronic axonal idiopathic polyneuropathy: is it really benign.
Samuelsson K, Press R
Curr Opin Neurol 2020 Oct;33(5):562-567. doi: 10.1097/WCO.0000000000000847. PMID: 32773448
Statins do not increase risk of polyneuropathy: A case-control study and literature review.
Warendorf JK, Vrancken AFJE, van Eijk RPA, Visser NA, van den Berg LH, Notermans NC
Neurology 2019 Apr 30;92(18):e2136-e2144. Epub 2019 Feb 8 doi: 10.1212/WNL.0000000000007148. PMID: 30737334
Intravenous immunoglobulin for Guillain-Barré syndrome.
Hughes RA, Swan AV, van Doorn PA
Cochrane Database Syst Rev 2014 Sep 19;2014(9):CD002063. doi: 10.1002/14651858.CD002063.pub6. PMID: 25238327Free PMC Article
Infectious neuropathy.
de Freitas MR
Curr Opin Neurol 2007 Oct;20(5):548-52. doi: 10.1097/WCO.0b013e32826fbca6. PMID: 17885443

Prognosis

Controversies in neuroimmunology: multiple sclerosis, vaccination, SARS-CoV-2 and other dilemas.
Reyes-Niño S, Rodríguez-Orozco JE, Moutran-Barroso HG, Kreinter-Rosembaun H, Gaviria-Carrillo M, Salej-Durán V, Mancera-Charry J, Villegas AC, Cuellar-Giraldo D, Torres-Sandoval JS, Gómez-Mazuera Á, Duque-Samper A, Toro-Gómez J
Biomedica 2022 Oct 31;42(Sp. 2):78-99. doi: 10.7705/biomedica.6366. PMID: 36322548Free PMC Article
Peripheral neuropathies.
Hanewinckel R, Ikram MA, Van Doorn PA
Handb Clin Neurol 2016;138:263-82. doi: 10.1016/B978-0-12-802973-2.00015-X. PMID: 27637963
The epidemiology and risk factors of chronic polyneuropathy.
Hanewinckel R, van Oijen M, Ikram MA, van Doorn PA
Eur J Epidemiol 2016 Jan;31(1):5-20. Epub 2015 Dec 23 doi: 10.1007/s10654-015-0094-6. PMID: 26700499Free PMC Article
Acquired peripheral neuropathy.
Chalk CH
Neurol Clin 1997 Aug;15(3):501-28. doi: 10.1016/s0733-8619(05)70331-5. PMID: 9227950
Chronic idiopathic polyneuropathy presenting in middle or old age: a clinical and electrophysiological study of 75 patients.
Notermans NC, Wokke JH, Franssen H, van der Graaf Y, Vermeulen M, van den Berg LH, Bär PR, Jennekens FG
J Neurol Neurosurg Psychiatry 1993 Oct;56(10):1066-71. doi: 10.1136/jnnp.56.10.1066. PMID: 7691991Free PMC Article

Clinical prediction guides

Efficacy of azathioprine and methotrexate in patients with chronic inflammatory demyelinating polyneuropathy (CIDP).
Mehreen S, Iftikhar S, Muhammad A, Aatif Siddique R, Shahid S
Pak J Pharm Sci 2023 Jul;36(4(Special)):1361-1365. PMID: 37606029
Clinical and genetic studies of thiamine metabolism dysfunction syndrome-4: case series and review of the literature.
Samur BM, Gümüş G, Canpolat M, Gümüş H, Per H, Cağlayan AO
Clin Dysmorphol 2022 Jul 1;31(3):125-131. Epub 2022 Jan 31 doi: 10.1097/MCD.0000000000000411. PMID: 35102031Free PMC Article
Thrombosis revealing POEMS syndrome. About a case.
Dumas C, Bienvenu FH, Hicks J, Weber E, Sève P
Ann Biol Clin (Paris) 2020 Apr 1;78(2):195-197. doi: 10.1684/abc.2020.1534. PMID: 32162605
Diagnostic value of symptoms in chronic polyneuropathy: The Erasmus Polyneuropathy Symptom Score.
Hanewinckel R, van Oijen M, Taams NE, Merkies ISJ, Notermans NC, Vrancken AFJE, Ikram MA, van Doorn PA
J Peripher Nerv Syst 2019 Sep;24(3):235-241. Epub 2019 Jul 9 doi: 10.1111/jns.12328. PMID: 31172622
Polyneuropathy relates to impairment in daily activities, worse gait, and fall-related injuries.
Hanewinckel R, Drenthen J, Verlinden VJA, Darweesh SKL, van der Geest JN, Hofman A, van Doorn PA, Ikram MA
Neurology 2017 Jul 4;89(1):76-83. Epub 2017 May 31 doi: 10.1212/WNL.0000000000004067. PMID: 28566544

Recent systematic reviews

Immunomodulatory treatment other than corticosteroids, immunoglobulin and plasma exchange for chronic inflammatory demyelinating polyradiculoneuropathy.
Mahdi-Rogers M, Brassington R, Gunn AA, van Doorn PA, Hughes RA
Cochrane Database Syst Rev 2017 May 8;5(5):CD003280. doi: 10.1002/14651858.CD003280.pub5. PMID: 28481421Free PMC Article
Corticosteroids for Guillain-Barré syndrome.
Hughes RA, Brassington R, Gunn AA, van Doorn PA
Cochrane Database Syst Rev 2016 Oct 24;10(10):CD001446. doi: 10.1002/14651858.CD001446.pub5. PMID: 27775812Free PMC Article
Interventions for fatigue in peripheral neuropathy.
White CM, van Doorn PA, Garssen MP, Stockley RC
Cochrane Database Syst Rev 2014 Dec 18;2014(12):CD008146. doi: 10.1002/14651858.CD008146.pub2. PMID: 25519471Free PMC Article
Intravenous immunoglobulin for Guillain-Barré syndrome.
Hughes RA, Swan AV, van Doorn PA
Cochrane Database Syst Rev 2014 Sep 19;2014(9):CD002063. doi: 10.1002/14651858.CD002063.pub6. PMID: 25238327Free PMC Article

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