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Neurodegenerative disease with dementia

MedGen UID:
1842356
•Concept ID:
C5681723
•
Disease or Syndrome
Orphanet: ORPHA98534

Professional guidelines

PubMed

New evidence on the management of Lewy body dementia.
Taylor JP, McKeith IG, Burn DJ, Boeve BF, Weintraub D, Bamford C, Allan LM, Thomas AJ, O'Brien JT
Lancet Neurol 2020 Feb;19(2):157-169. Epub 2019 Sep 10 doi: 10.1016/S1474-4422(19)30153-X. PMID: 31519472Free PMC Article
The Alzheimer's Disease Clinical Spectrum: Diagnosis and Management.
Atri A
Med Clin North Am 2019 Mar;103(2):263-293. doi: 10.1016/j.mcna.2018.10.009. PMID: 30704681
Current understanding of Alzheimer's disease diagnosis and treatment.
Weller J, Budson A
F1000Res 2018;7 Epub 2018 Jul 31 doi: 10.12688/f1000research.14506.1. PMID: 30135715Free PMC Article

Recent clinical studies

Etiology

Alzheimer's Disease: Treatment Strategies and Their Limitations.
Passeri E, Elkhoury K, Morsink M, Broersen K, Linder M, Tamayol A, Malaplate C, Yen FT, Arab-Tehrany E
Int J Mol Sci 2022 Nov 12;23(22) doi: 10.3390/ijms232213954. PMID: 36430432Free PMC Article
Frontotemporal Dementia - Current Concepts.
Puppala GK, Gorthi SP, Chandran V, Gundabolu G
Neurol India 2021 Sep-Oct;69(5):1144-1152. doi: 10.4103/0028-3886.329593. PMID: 34747778
The role of nutrition in Alzheimer's disease.
Śliwińska S, Jeziorek M
Rocz Panstw Zakl Hig 2021;72(1):29-39. doi: 10.32394/rpzh.2021.0154. PMID: 33882663
Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
Leng F, Edison P
Nat Rev Neurol 2021 Mar;17(3):157-172. Epub 2020 Dec 14 doi: 10.1038/s41582-020-00435-y. PMID: 33318676
Comprehensive Review on Alzheimer's Disease: Causes and Treatment.
Breijyeh Z, Karaman R
Molecules 2020 Dec 8;25(24) doi: 10.3390/molecules25245789. PMID: 33302541Free PMC Article

Diagnosis

Frontotemporal Dementia - Current Concepts.
Puppala GK, Gorthi SP, Chandran V, Gundabolu G
Neurol India 2021 Sep-Oct;69(5):1144-1152. doi: 10.4103/0028-3886.329593. PMID: 34747778
Comprehensive Review on Alzheimer's Disease: Causes and Treatment.
Breijyeh Z, Karaman R
Molecules 2020 Dec 8;25(24) doi: 10.3390/molecules25245789. PMID: 33302541Free PMC Article
New evidence on the management of Lewy body dementia.
Taylor JP, McKeith IG, Burn DJ, Boeve BF, Weintraub D, Bamford C, Allan LM, Thomas AJ, O'Brien JT
Lancet Neurol 2020 Feb;19(2):157-169. Epub 2019 Sep 10 doi: 10.1016/S1474-4422(19)30153-X. PMID: 31519472Free PMC Article
Alzheimer's Disease: Past, Present, and Future.
Bondi MW, Edmonds EC, Salmon DP
J Int Neuropsychol Soc 2017 Oct;23(9-10):818-831. doi: 10.1017/S135561771700100X. PMID: 29198280Free PMC Article
Frontotemporal dementia.
Bang J, Spina S, Miller BL
Lancet 2015 Oct 24;386(10004):1672-82. doi: 10.1016/S0140-6736(15)00461-4. PMID: 26595641Free PMC Article

Therapy

Mitochondrial dysfunction in neurodegenerative disorders.
Klemmensen MM, Borrowman SH, Pearce C, Pyles B, Chandra B
Neurotherapeutics 2024 Jan;21(1):e00292. Epub 2023 Dec 19 doi: 10.1016/j.neurot.2023.10.002. PMID: 38241161Free PMC Article
Role of neuroinflammation in neurodegeneration development.
Zhang W, Xiao D, Mao Q, Xia H
Signal Transduct Target Ther 2023 Jul 12;8(1):267. doi: 10.1038/s41392-023-01486-5. PMID: 37433768Free PMC Article
Alzheimer's Disease: Treatment Strategies and Their Limitations.
Passeri E, Elkhoury K, Morsink M, Broersen K, Linder M, Tamayol A, Malaplate C, Yen FT, Arab-Tehrany E
Int J Mol Sci 2022 Nov 12;23(22) doi: 10.3390/ijms232213954. PMID: 36430432Free PMC Article
Huntington's disease: diagnosis and management.
Stoker TB, Mason SL, Greenland JC, Holden ST, Santini H, Barker RA
Pract Neurol 2022 Feb;22(1):32-41. Epub 2021 Aug 19 doi: 10.1136/practneurol-2021-003074. PMID: 34413240
Potential Benefits of Nobiletin, A Citrus Flavonoid, against Alzheimer's Disease and Parkinson's Disease.
Nakajima A, Ohizumi Y
Int J Mol Sci 2019 Jul 10;20(14) doi: 10.3390/ijms20143380. PMID: 31295812Free PMC Article

Prognosis

Alzheimer disease.
Knopman DS, Amieva H, Petersen RC, Chételat G, Holtzman DM, Hyman BT, Nixon RA, Jones DT
Nat Rev Dis Primers 2021 May 13;7(1):33. doi: 10.1038/s41572-021-00269-y. PMID: 33986301Free PMC Article
The role of nutrition in Alzheimer's disease.
Śliwińska S, Jeziorek M
Rocz Panstw Zakl Hig 2021;72(1):29-39. doi: 10.32394/rpzh.2021.0154. PMID: 33882663
Hearing and dementia: from ears to brain.
Johnson JCS, Marshall CR, Weil RS, Bamiou DE, Hardy CJD, Warren JD
Brain 2021 Mar 3;144(2):391-401. doi: 10.1093/brain/awaa429. PMID: 33351095Free PMC Article
Comprehensive Review on Alzheimer's Disease: Causes and Treatment.
Breijyeh Z, Karaman R
Molecules 2020 Dec 8;25(24) doi: 10.3390/molecules25245789. PMID: 33302541Free PMC Article
Alzheimer's Disease: Past, Present, and Future.
Bondi MW, Edmonds EC, Salmon DP
J Int Neuropsychol Soc 2017 Oct;23(9-10):818-831. doi: 10.1017/S135561771700100X. PMID: 29198280Free PMC Article

Clinical prediction guides

The promise of music therapy for Alzheimer's disease: A review.
Matziorinis AM, Koelsch S
Ann N Y Acad Sci 2022 Oct;1516(1):11-17. Epub 2022 Jul 18 doi: 10.1111/nyas.14864. PMID: 35851957Free PMC Article
Microglia in the Neuroinflammatory Pathogenesis of Alzheimer's Disease and Related Therapeutic Targets.
Cai Y, Liu J, Wang B, Sun M, Yang H
Front Immunol 2022;13:856376. Epub 2022 Apr 26 doi: 10.3389/fimmu.2022.856376. PMID: 35558075Free PMC Article
Hearing and dementia: from ears to brain.
Johnson JCS, Marshall CR, Weil RS, Bamiou DE, Hardy CJD, Warren JD
Brain 2021 Mar 3;144(2):391-401. doi: 10.1093/brain/awaa429. PMID: 33351095Free PMC Article
Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
Leng F, Edison P
Nat Rev Neurol 2021 Mar;17(3):157-172. Epub 2020 Dec 14 doi: 10.1038/s41582-020-00435-y. PMID: 33318676
Alzheimer's Disease: Past, Present, and Future.
Bondi MW, Edmonds EC, Salmon DP
J Int Neuropsychol Soc 2017 Oct;23(9-10):818-831. doi: 10.1017/S135561771700100X. PMID: 29198280Free PMC Article

Recent systematic reviews

Physical activity as a protective factor for dementia and Alzheimer's disease: systematic review, meta-analysis and quality assessment of cohort and case-control studies.
Iso-Markku P, Kujala UM, Knittle K, Polet J, Vuoksimaa E, Waller K
Br J Sports Med 2022 Jun;56(12):701-709. Epub 2022 Mar 17 doi: 10.1136/bjsports-2021-104981. PMID: 35301183Free PMC Article
Antipsychotics for agitation and psychosis in people with Alzheimer's disease and vascular dementia.
Mühlbauer V, Möhler R, Dichter MN, Zuidema SU, Köpke S, Luijendijk HJ
Cochrane Database Syst Rev 2021 Dec 17;12(12):CD013304. doi: 10.1002/14651858.CD013304.pub2. PMID: 34918337Free PMC Article
The Amyloid-β Pathway in Alzheimer's Disease.
Hampel H, Hardy J, Blennow K, Chen C, Perry G, Kim SH, Villemagne VL, Aisen P, Vendruscolo M, Iwatsubo T, Masters CL, Cho M, Lannfelt L, Cummings JL, Vergallo A
Mol Psychiatry 2021 Oct;26(10):5481-5503. Epub 2021 Aug 30 doi: 10.1038/s41380-021-01249-0. PMID: 34456336Free PMC Article
Anticholinergic drugs and the risk of dementia: A systematic review and meta-analysis.
Zheng YB, Shi L, Zhu XM, Bao YP, Bai LJ, Li JQ, Liu JJ, Han Y, Shi J, Lu L
Neurosci Biobehav Rev 2021 Aug;127:296-306. Epub 2021 Apr 29 doi: 10.1016/j.neubiorev.2021.04.031. PMID: 33933505
The Prevalence of Dementia: A Systematic Review and Meta-Analysis.
Cao Q, Tan CC, Xu W, Hu H, Cao XP, Dong Q, Tan L, Yu JT
J Alzheimers Dis 2020;73(3):1157-1166. doi: 10.3233/JAD-191092. PMID: 31884487

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