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Decreased circulating calcitonin concentration

MedGen UID:
1841930
•Concept ID:
C5826753
•
Finding
Synonym: Calcitonin low in blood
 
HPO: HP:0034903

Definition

Concentration of calcitonin, a 32-amino acid polypeptide hormone that is produced primarily by the parafollicular cells of the thyroid, in the blood circulation below the lower limit of normal. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDecreased circulating calcitonin concentration

Recent clinical studies

Etiology

Kynurenine pathway alteration in acute pancreatitis and its role as a biomarker of infected necrosis.
Jakkampudi A, Sarkar P, Unnisa M, Patil A, Koutarapu C, Jaggaiahgari S, Naik P, Sarkar S, Prasanna A, Chintaluri S, Reddy DN, Beedu SR, Talukdar R
Pancreatology 2023 Sep;23(6):589-600. Epub 2023 Jul 5 doi: 10.1016/j.pan.2023.07.003. PMID: 37438173
Afferent signals regulating food intake.
Bray GA
Proc Nutr Soc 2000 Aug;59(3):373-84. doi: 10.1017/s0029665100000422. PMID: 10997653
Diagnostic and therapeutic aspects of calciotropic hormones.
Cormier C, Souberbielle JC, Kindermans C
Curr Opin Rheumatol 1997 Jul;9(4):370-6. doi: 10.1097/00002281-199707000-00016. PMID: 9229185
Absence of vasoactive peptide release from brain to cerebral circulation during onset of migraine with aura.
Friberg L, Olesen J, Olsen TS, Karle A, Ekman R, Fahrenkrug J
Cephalalgia 1994 Feb;14(1):47-54. doi: 10.1046/j.1468-2982.1994.1401047.x. PMID: 7515329
The physiology of calcitonin gene-related peptide in the islet compared with that of islet amyloid polypeptide (amylin).
Bretherton-Watt D, Ghatei MA, Jamal H, Gilbey SG, Jones PM, Bloom SR
Ann N Y Acad Sci 1992 Jun 30;657:299-312. doi: 10.1111/j.1749-6632.1992.tb22777.x. PMID: 1637089

Diagnosis

Prognostic and diagnostic value of eosinopenia, C-reactive protein, procalcitonin, and circulating cell-free DNA in critically ill patients admitted with suspicion of sepsis.
Garnacho-Montero J, Huici-Moreno MJ, Gutiérrez-Pizarraya A, López I, Márquez-Vácaro JA, Macher H, Guerrero JM, Puppo-Moreno A
Crit Care 2014 Jun 5;18(3):R116. doi: 10.1186/cc13908. PMID: 24903083Free PMC Article
Diagnostic and therapeutic aspects of calciotropic hormones.
Cormier C, Souberbielle JC, Kindermans C
Curr Opin Rheumatol 1997 Jul;9(4):370-6. doi: 10.1097/00002281-199707000-00016. PMID: 9229185
The parathyroid calcium receptor: a novel therapeutic target for treating hyperparathyroidism.
Nemeth EF, Steffey ME, Fox J
Pediatr Nephrol 1996 Jun;10(3):275-9. doi: 10.1007/BF00866757. PMID: 8792389
Absence of vasoactive peptide release from brain to cerebral circulation during onset of migraine with aura.
Friberg L, Olesen J, Olsen TS, Karle A, Ekman R, Fahrenkrug J
Cephalalgia 1994 Feb;14(1):47-54. doi: 10.1046/j.1468-2982.1994.1401047.x. PMID: 7515329
The physiology of calcitonin gene-related peptide in the islet compared with that of islet amyloid polypeptide (amylin).
Bretherton-Watt D, Ghatei MA, Jamal H, Gilbey SG, Jones PM, Bloom SR
Ann N Y Acad Sci 1992 Jun 30;657:299-312. doi: 10.1111/j.1749-6632.1992.tb22777.x. PMID: 1637089

Therapy

Testosterone supplementation, glucocorticoid milieu and bone homeostasis in the ageing male.
Ajdžanović VZ, Filipović BR, Šošić Jurjević BT, Milošević VL
Fundam Clin Pharmacol 2017 Aug;31(4):372-382. Epub 2017 Mar 1 doi: 10.1111/fcp.12277. PMID: 28186359
Androgen replacement in aging men.
Francis RM
Calcif Tissue Int 2001 Oct;69(4):235-8. doi: 10.1007/s00223-001-1051-9. PMID: 11730258
Diagnostic and therapeutic aspects of calciotropic hormones.
Cormier C, Souberbielle JC, Kindermans C
Curr Opin Rheumatol 1997 Jul;9(4):370-6. doi: 10.1097/00002281-199707000-00016. PMID: 9229185
Absence of vasoactive peptide release from brain to cerebral circulation during onset of migraine with aura.
Friberg L, Olesen J, Olsen TS, Karle A, Ekman R, Fahrenkrug J
Cephalalgia 1994 Feb;14(1):47-54. doi: 10.1046/j.1468-2982.1994.1401047.x. PMID: 7515329
Hormonal alterations and osteoporotic syndromes.
Avioli LV
J Bone Miner Res 1993 Dec;8 Suppl 2:S511-4. doi: 10.1002/jbmr.5650081316. PMID: 8122520

Prognosis

Kynurenine pathway alteration in acute pancreatitis and its role as a biomarker of infected necrosis.
Jakkampudi A, Sarkar P, Unnisa M, Patil A, Koutarapu C, Jaggaiahgari S, Naik P, Sarkar S, Prasanna A, Chintaluri S, Reddy DN, Beedu SR, Talukdar R
Pancreatology 2023 Sep;23(6):589-600. Epub 2023 Jul 5 doi: 10.1016/j.pan.2023.07.003. PMID: 37438173
Presepsin As a Biomarker for Evaluating Prognosis and Early Innate Immune Response of Out-of-Hospital Cardiac Arrest Patients After Return of Spontaneous Circulation.
Qi Z, Zhang Q, Liu B, Shao F, Li C
Crit Care Med 2019 Jul;47(7):e538-e546. doi: 10.1097/CCM.0000000000003764. PMID: 30985453
Prognostic and diagnostic value of eosinopenia, C-reactive protein, procalcitonin, and circulating cell-free DNA in critically ill patients admitted with suspicion of sepsis.
Garnacho-Montero J, Huici-Moreno MJ, Gutiérrez-Pizarraya A, López I, Márquez-Vácaro JA, Macher H, Guerrero JM, Puppo-Moreno A
Crit Care 2014 Jun 5;18(3):R116. doi: 10.1186/cc13908. PMID: 24903083Free PMC Article
Treatment evaluation, follow-up and familial screening of medullary thyroid carcinoma by highly specific calcitonin measurements.
Ainahi A, Kebbou M, Timinouni M, Benabdeljalil N, Oufara S
Indian J Cancer 2006 Apr-Jun;43(2):75-9. doi: 10.4103/0019-509x.25888. PMID: 16790944
Effect of oxygen inhalation on systemic, central, and splanchnic haemodynamics in cirrhosis.
Møller S, Becker U, Schifter S, Abrahamsen J, Henriksen JH
J Hepatol 1996 Sep;25(3):316-28. doi: 10.1016/s0168-8278(96)80118-8. PMID: 8895011

Clinical prediction guides

Kynurenine pathway alteration in acute pancreatitis and its role as a biomarker of infected necrosis.
Jakkampudi A, Sarkar P, Unnisa M, Patil A, Koutarapu C, Jaggaiahgari S, Naik P, Sarkar S, Prasanna A, Chintaluri S, Reddy DN, Beedu SR, Talukdar R
Pancreatology 2023 Sep;23(6):589-600. Epub 2023 Jul 5 doi: 10.1016/j.pan.2023.07.003. PMID: 37438173
Adrenomedullin in the kidney-renal physiological and pathophysiological roles.
Nishikimi T
Curr Med Chem 2007;14(15):1689-99. doi: 10.2174/092986707780830943. PMID: 17584073
Circulating calcitonin gene-related peptide and its placental origins in normotensive and preeclamptic pregnancies.
Dong YL, Chauhan M, Green KE, Vegiraju S, Wang HQ, Hankins GD, Yallampalli C
Am J Obstet Gynecol 2006 Dec;195(6):1657-67. Epub 2006 Sep 25 doi: 10.1016/j.ajog.2006.04.006. PMID: 16996466
Role of calcitonin gene-related peptide in the vascular system on the development of the hyperdynamic circulation in conscious cirrhotic rats.
Hori N, Okanoue T, Sawa Y, Kashima K
J Hepatol 1997 May;26(5):1111-9. doi: 10.1016/s0168-8278(97)80120-1. PMID: 9186842
Absence of vasoactive peptide release from brain to cerebral circulation during onset of migraine with aura.
Friberg L, Olesen J, Olsen TS, Karle A, Ekman R, Fahrenkrug J
Cephalalgia 1994 Feb;14(1):47-54. doi: 10.1046/j.1468-2982.1994.1401047.x. PMID: 7515329

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