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Elongated mitochondria

MedGen UID:
1841923
Concept ID:
C5826594
Finding
HPO: HP:0034692

Definition

Increase in length of mitochondria. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVElongated mitochondria

Professional guidelines

PubMed

Aurell M, Svalander C, Wallin L, Alling C
Kidney Int 1981 Nov;20(5):663-70. doi: 10.1038/ki.1981.191. PMID: 7343714

Recent clinical studies

Etiology

Cartes-Saavedra B, Lagos D, Macuada J, Arancibia D, Burté F, Sjöberg-Herrera MK, Andrés ME, Horvath R, Yu-Wai-Man P, Hajnóczky G, Eisner V
Proc Natl Acad Sci U S A 2023 Mar 21;120(12):e2207471120. Epub 2023 Mar 16 doi: 10.1073/pnas.2207471120. PMID: 36927155Free PMC Article
Vasconcellos AF, Melo RM, Mandacaru SC, de Oliveira LS, de Oliveira AS, Moraes ECDS, Trugilho MRO, Ricart CAO, Báo SN, Resende RO, Charneau S
Front Cell Infect Microbiol 2022;12:920425. Epub 2022 Jun 15 doi: 10.3389/fcimb.2022.920425. PMID: 35782121Free PMC Article
Liu Y, Han M, Li X, Wang H, Ma M, Zhang S, Guo Y, Wang S, Wang Y, Duan N, Xu B, Yin J, Yao Y
Hum Reprod 2017 Dec 1;32(12):2465-2473. doi: 10.1093/humrep/dex309. PMID: 29045673
Wan J, Steffen J, Yourshaw M, Mamsa H, Andersen E, Rudnik-Schöneborn S, Pope K, Howell KB, McLean CA, Kornberg AJ, Joseph J, Lockhart PJ, Zerres K, Ryan MM, Nelson SF, Koehler CM, Jen JC
Brain 2016 Nov 1;139(11):2877-2890. doi: 10.1093/brain/aww212. PMID: 27543974Free PMC Article
Chou CH, Lin CC, Yang MC, Wei CC, Liao HD, Lin RC, Tu WY, Kao TC, Hsu CM, Cheng JT, Chou AK, Lee CI, Loh JK, Howng SL, Hong YR
PLoS One 2012;7(11):e49112. Epub 2012 Nov 20 doi: 10.1371/journal.pone.0049112. PMID: 23185298Free PMC Article

Diagnosis

Liao JZ, Chung HL, Shih C, Wong KKL, Dutta D, Nil Z, Burns CG, Kanca O, Park YJ, Zuo Z, Marcogliese PC, Sew K, Bellen HJ, Verheyen EM
Nat Commun 2024 Apr 18;15(1):3326. doi: 10.1038/s41467-024-47623-8. PMID: 38637532Free PMC Article
Verrigni D, Di Nottia M, Ardissone A, Baruffini E, Nasca A, Legati A, Bellacchio E, Fagiolari G, Martinelli D, Fusco L, Battaglia D, Trani G, Versienti G, Marchet S, Torraco A, Rizza T, Verardo M, D'Amico A, Diodato D, Moroni I, Lamperti C, Petrini S, Moggio M, Goffrini P, Ghezzi D, Carrozzo R, Bertini E
Hum Mutat 2019 May;40(5):601-618. Epub 2019 Mar 9 doi: 10.1002/humu.23729. PMID: 30801875
Yao CH, Wang R, Wang Y, Kung CP, Weber JD, Patti GJ
Elife 2019 Jan 29;8 doi: 10.7554/eLife.41351. PMID: 30694178Free PMC Article
Lemos V, de Oliveira RM, Naia L, Szegö É, Ramos E, Pinho S, Magro F, Cavadas C, Rego AC, Costa V, Outeiro TF, Gomes P
Hum Mol Genet 2017 Nov 1;26(21):4105-4117. doi: 10.1093/hmg/ddx298. PMID: 28973648
Bosman C, Fusilli S, Bisceglia M, Musto P, Corsi A
Acta Haematol 1996;96(1):50-6. doi: 10.1159/000203715. PMID: 8677762

Therapy

Kornfeld OS, Qvit N, Haileselassie B, Shamloo M, Bernardi P, Mochly-Rosen D
Sci Rep 2018 Sep 19;8(1):14034. doi: 10.1038/s41598-018-32228-1. PMID: 30232469Free PMC Article
Caino MC, Altieri DC
Cell Cycle 2015;14(20):3242-7. doi: 10.1080/15384101.2015.1084448. PMID: 26317663Free PMC Article
Fujimura K, Wakino S, Minakuchi H, Hasegawa K, Hosoya K, Komatsu M, Kaneko Y, Shinozuka K, Washida N, Kanda T, Tokuyama H, Hayashi K, Itoh H
PLoS One 2014;9(4):e94373. Epub 2014 Apr 18 doi: 10.1371/journal.pone.0094373. PMID: 24747517Free PMC Article
Melegh B, Trombitás K
Neuropediatrics 1997 Oct;28(5):257-61. doi: 10.1055/s-2007-973710. PMID: 9413004
Aurell M, Svalander C, Wallin L, Alling C
Kidney Int 1981 Nov;20(5):663-70. doi: 10.1038/ki.1981.191. PMID: 7343714

Prognosis

Cantarero L, García-Vargas G, Hoenicka J, Palau F
Biol Open 2023 Apr 15;12(4) Epub 2023 Apr 3 doi: 10.1242/bio.059707. PMID: 36912213Free PMC Article
Lemos V, de Oliveira RM, Naia L, Szegö É, Ramos E, Pinho S, Magro F, Cavadas C, Rego AC, Costa V, Outeiro TF, Gomes P
Hum Mol Genet 2017 Nov 1;26(21):4105-4117. doi: 10.1093/hmg/ddx298. PMID: 28973648

Clinical prediction guides

Liao JZ, Chung HL, Shih C, Wong KKL, Dutta D, Nil Z, Burns CG, Kanca O, Park YJ, Zuo Z, Marcogliese PC, Sew K, Bellen HJ, Verheyen EM
Nat Commun 2024 Apr 18;15(1):3326. doi: 10.1038/s41467-024-47623-8. PMID: 38637532Free PMC Article
Cantarero L, García-Vargas G, Hoenicka J, Palau F
Biol Open 2023 Apr 15;12(4) Epub 2023 Apr 3 doi: 10.1242/bio.059707. PMID: 36912213Free PMC Article
Phadwal K, Tang QY, Luijten I, Zhao JF, Corcoran B, Semple RK, Ganley IG, MacRae VE
Int J Mol Sci 2023 Jan 13;24(2) doi: 10.3390/ijms24021643. PMID: 36675156Free PMC Article
Tan EP, McGreal SR, Graw S, Tessman R, Koppel SJ, Dhakal P, Zhang Z, Machacek M, Zachara NE, Koestler DC, Peterson KR, Thyfault JP, Swerdlow RH, Krishnamurthy P, DiTacchio L, Apte U, Slawson C
J Biol Chem 2017 Sep 8;292(36):14940-14962. Epub 2017 Jul 24 doi: 10.1074/jbc.M117.797944. PMID: 28739801Free PMC Article
Wan J, Steffen J, Yourshaw M, Mamsa H, Andersen E, Rudnik-Schöneborn S, Pope K, Howell KB, McLean CA, Kornberg AJ, Joseph J, Lockhart PJ, Zerres K, Ryan MM, Nelson SF, Koehler CM, Jen JC
Brain 2016 Nov 1;139(11):2877-2890. doi: 10.1093/brain/aww212. PMID: 27543974Free PMC Article

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