U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal fetal gastrointestinal system morphology

MedGen UID:
1814358
Concept ID:
C5676794
Congenital Abnormality
HPO: HP:0034207

Definition

An anomalous structural finding of the fetal gastrointestinal system. Terms in this subhierarchy are restricted to findings that can only be observed in the prenatal period. Other HPO terms can also be used to describe fetal phenotypes. [from HPO]

Professional guidelines

PubMed

Schindewolf E, Moldenhauer JS
Curr Opin Obstet Gynecol 2020 Apr;32(2):134-139. doi: 10.1097/GCO.0000000000000613. PMID: 32039977
Basurto D, Russo FM, Van der Veeken L, Van der Merwe J, Hooper S, Benachi A, De Bie F, Gomez O, Deprest J
Best Pract Res Clin Obstet Gynaecol 2019 Jul;58:93-106. Epub 2019 Jan 5 doi: 10.1016/j.bpobgyn.2018.12.010. PMID: 30772144
Haddock C, Skarsgard ED
Expert Rev Gastroenterol Hepatol 2018 Apr;12(4):405-415. Epub 2018 Feb 16 doi: 10.1080/17474124.2018.1438890. PMID: 29419329

Recent clinical studies

Etiology

Tonni G, Koçak Ç, Grisolia G, Rizzo G, Araujo Júnior E, Werner H, Ruano R, Sepulveda W, Bonasoni MP, Lituania M; “International Perinatology Research Group (IPRG)”
Fetal Pediatr Pathol 2023 Aug;42(4):651-674. Epub 2023 May 17 doi: 10.1080/15513815.2023.2206905. PMID: 37195727
Haddock C, Skarsgard ED
Expert Rev Gastroenterol Hepatol 2018 Apr;12(4):405-415. Epub 2018 Feb 16 doi: 10.1080/17474124.2018.1438890. PMID: 29419329
Kenny SE, Tam PK, Garcia-Barcelo M
Semin Pediatr Surg 2010 Aug;19(3):194-200. doi: 10.1053/j.sempedsurg.2010.03.004. PMID: 20610192
Rochon M, Eddleman K
Obstet Gynecol Clin North Am 2004 Mar;31(1):61-99. doi: 10.1016/S0889-8545(03)00123-2. PMID: 15062448
Kahn E
Pediatr Dev Pathol 2004 Mar-Apr;7(2):109-24. Epub 2004 Mar 4 doi: 10.1007/s10024-003-0307-y. PMID: 14994122

Diagnosis

Tonni G, Koçak Ç, Grisolia G, Rizzo G, Araujo Júnior E, Werner H, Ruano R, Sepulveda W, Bonasoni MP, Lituania M; “International Perinatology Research Group (IPRG)”
Fetal Pediatr Pathol 2023 Aug;42(4):651-674. Epub 2023 May 17 doi: 10.1080/15513815.2023.2206905. PMID: 37195727
Rich BS, Bornstein E, Dolgin SE
Pediatr Rev 2022 May 1;43(5):266-274. doi: 10.1542/pir.2021-005177. PMID: 35490204
Society for Maternal-Fetal Medicine, Monteagudo A
Am J Obstet Gynecol 2020 Dec;223(6):B5-B8. Epub 2020 Nov 7 doi: 10.1016/j.ajog.2020.08.176. PMID: 33168213
Trappey AF 3rd, Hirose S
Semin Pediatr Surg 2017 Apr;26(2):78-86. Epub 2017 Feb 11 doi: 10.1053/j.sempedsurg.2017.02.003. PMID: 28550875
Leboulanger N, Garabédian EN
Orphanet J Rare Dis 2011 Dec 7;6:81. doi: 10.1186/1750-1172-6-81. PMID: 22151899Free PMC Article

Therapy

Romanowska-Próchnicka K, Felis-Giemza A, Olesińska M, Wojdasiewicz P, Paradowska-Gorycka A, Szukiewicz D
Int J Mol Sci 2021 Mar 13;22(6) doi: 10.3390/ijms22062922. PMID: 33805757Free PMC Article
Society for Maternal-Fetal Medicine (SMFM), Gandhi M, Rac MWF, McKinney J
Am J Obstet Gynecol 2019 Dec;221(6):B16-B18. doi: 10.1016/j.ajog.2019.09.024. PMID: 31787159
Haddock C, Skarsgard ED
Expert Rev Gastroenterol Hepatol 2018 Apr;12(4):405-415. Epub 2018 Feb 16 doi: 10.1080/17474124.2018.1438890. PMID: 29419329
Caputo C, Wood E, Jabbour L
Birth Defects Res C Embryo Today 2016 Jun;108(2):174-80. Epub 2016 Jun 13 doi: 10.1002/bdrc.21129. PMID: 27297122
Scheig R
Am Fam Physician 1974 Oct;10(4):158-64. PMID: 4414786

Prognosis

Romanowska-Próchnicka K, Felis-Giemza A, Olesińska M, Wojdasiewicz P, Paradowska-Gorycka A, Szukiewicz D
Int J Mol Sci 2021 Mar 13;22(6) doi: 10.3390/ijms22062922. PMID: 33805757Free PMC Article
Schindewolf E, Moldenhauer JS
Curr Opin Obstet Gynecol 2020 Apr;32(2):134-139. doi: 10.1097/GCO.0000000000000613. PMID: 32039977
Logjes RJH, Breugem CC, Van Haaften G, Paes EC, Sperber GH, van den Boogaard MH, Farlie PG
Am J Med Genet A 2018 Jun;176(6):1349-1368. Epub 2018 Apr 25 doi: 10.1002/ajmg.a.38718. PMID: 29696787
Leboulanger N, Garabédian EN
Orphanet J Rare Dis 2011 Dec 7;6:81. doi: 10.1186/1750-1172-6-81. PMID: 22151899Free PMC Article
Kenny SE, Tam PK, Garcia-Barcelo M
Semin Pediatr Surg 2010 Aug;19(3):194-200. doi: 10.1053/j.sempedsurg.2010.03.004. PMID: 20610192

Clinical prediction guides

Rohrer L, Vial Y, Hanquinet S, Tenisch E, Alamo L
Eur J Radiol 2020 Apr;125:108859. Epub 2020 Feb 5 doi: 10.1016/j.ejrad.2020.108859. PMID: 32078893
Boer LL, Morava E, Klein WM, Schepens-Franke AN, Oostra RJ
Birth Defects Res 2017 Jun 1;109(10):791-804. Epub 2017 May 16 doi: 10.1002/bdr2.1049. PMID: 28509418
Kim JH, Kinugasa Y, Hwang SE, Murakami G, Rodríguez-Vázquez JF, Cho BH
Surg Radiol Anat 2015 Mar;37(2):187-97. Epub 2014 Jul 10 doi: 10.1007/s00276-014-1336-0. PMID: 25008480
Page R, Ferraro ZM, Moretti F, Fung KF
J Pregnancy 2014;2014:239406. Epub 2014 Dec 22 doi: 10.1155/2014/239406. PMID: 25587450Free PMC Article
Brosens E, Ploeg M, van Bever Y, Koopmans AE, IJsselstijn H, Rottier RJ, Wijnen R, Tibboel D, de Klein A
Eur J Med Genet 2014 Aug;57(8):440-52. Epub 2014 Jun 13 doi: 10.1016/j.ejmg.2014.05.009. PMID: 24931924

Recent systematic reviews

Powel JE, Sham CE, Spiliopoulos M, Ferreira CR, Rosenthal E, Sinkovskaya ES, Brown S, Jelin AC, Al-Kouatly HB
Clin Genet 2022 Oct;102(4):262-287. Epub 2022 Jul 21 doi: 10.1111/cge.14188. PMID: 35802600Free PMC Article
Rossi AC, Prefumo F
Eur J Obstet Gynecol Reprod Biol 2017 Mar;210:201-206. Epub 2016 Dec 29 doi: 10.1016/j.ejogrb.2016.12.024. PMID: 28061423
Taghavi K, Sharpe C, Stringer MD
J Pediatr Urol 2017 Feb;13(1):7-15. Epub 2016 Oct 8 doi: 10.1016/j.jpurol.2016.09.003. PMID: 27889224
Caputo C, Wood E, Jabbour L
Birth Defects Res C Embryo Today 2016 Jun;108(2):174-80. Epub 2016 Jun 13 doi: 10.1002/bdrc.21129. PMID: 27297122
Tan YW, Khalil A, Kakade M, Carvalho JS, Bradley S, Cleeve S, Giuliani S
J Pediatr 2016 Apr;171:153-62.e1-3. Epub 2016 Feb 8 doi: 10.1016/j.jpeds.2015.12.074. PMID: 26868865

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...