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Anti-salivary protein antibody positivity

MedGen UID:
1814233
•Concept ID:
C5676661
•
Finding
Synonym: Anti-SP1 antibody positivity
 
HPO: HP:0034064

Definition

The presence of autoantibodies (immunoglobulins) in the serum that react against salivary protein. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnti-salivary protein antibody positivity

Recent clinical studies

Therapy

The Diagnostic Performance of Early Sjögren's Syndrome Autoantibodies in Juvenile Sjögren's Syndrome: The University of Florida Pediatric Cohort Study.
Thatayatikom A, Jun I, Bhattacharyya I, Berg K, Lee YJ, Kim Y, Adewumi A, Zhang W, Thatayatikom S, Shah A, Beal C, Modica R, Elder ME, Cha S
Front Immunol 2021;12:704193. Epub 2021 Jun 25 doi: 10.3389/fimmu.2021.704193. PMID: 34249010Free PMC Article

Clinical prediction guides

The Diagnostic Performance of Early Sjögren's Syndrome Autoantibodies in Juvenile Sjögren's Syndrome: The University of Florida Pediatric Cohort Study.
Thatayatikom A, Jun I, Bhattacharyya I, Berg K, Lee YJ, Kim Y, Adewumi A, Zhang W, Thatayatikom S, Shah A, Beal C, Modica R, Elder ME, Cha S
Front Immunol 2021;12:704193. Epub 2021 Jun 25 doi: 10.3389/fimmu.2021.704193. PMID: 34249010Free PMC Article
Antibodies to AB blood group antigens mimic anti-salivary duct autoantibodies in patients with limited sicca symptoms.
Goldblatt F, Beroukas D, Gillis D, Cavill D, Bradwell A, Rischmueller M, Gordon TP
J Rheumatol 2000 Oct;27(10):2382-8. PMID: 11036834

Supplemental Content

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    Clinical resources

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    Reviews

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